List of works - Volodymyr G. Bdzhola

A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2α Complex Structures

scientific article

ASK1 pharmacophore model derived from diverse classes of inhibitors.

scientific article published on 12 August 2014

Ab initio parameterization of YFF1, a universal force field for drug-design applications

scientific article published on 12 May 2011

Augmenting a training dataset of the generative diffusion model for molecular docking with artificial binding pockets

scientific article published in 2024

Design and synthesis of novel protein kinase CK2 inhibitors on the base of 4-aminothieno[2,3-d]pyrimidines.

scientific article published on 9 March 2016

Design, synthesis and biological evaluation of 2-aminopyrimidinones and their 6-aza-analogs as a new class of CK2 inhibitors.

scientific article

Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1.

scientific article published on 21 March 2016

Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1.

scientific article

Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors.

scientific article

Design, synthesis and evaluation of 3-quinoline carboxylic acids as new inhibitors of protein kinase CK2.

scientific article published on 2 September 2016

Discovery and characterization of synthetic 4'-hydroxyflavones-New CK2 inhibitors from flavone family.

scientific article published on 13 August 2013

Discovery of potent anti-tuberculosis agents targeting leucyl-tRNA synthetase.

scientific article published on 16 January 2016

Electrochemical screening of the indole/quinolone derivatives as potential protein kinase CK2 inhibitors

scientific article published on 28 November 2011

Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2.

scientific article

Evaluation of 4,5,6,7-tetrahalogeno-1H-isoindole-1,3(2H)-diones as inhibitors of human protein kinase CK2.

scientific article published on 20 November 2007

Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1)

scientific article published on 30 March 2011

Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one.

scientific article

Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one.

scientific article published on 28 March 2015

Identification of dual-targeted <i>Mycobacterium tuberculosis</i> aminoacyl-tRNA synthetase inhibitors using machine learning

scientific article published in 2022

Identification of novel PARP-1 inhibitors by structure-based virtual screening.

scientific article published on 10 September 2013

Kirchhoff atomic charges fitted to multipole moments: implementation for a virtual screening system.

scientific article published in June 2008

Novel isoniazid derivative as promising antituberculosis agent

scientific article published on 14 July 2020

Rational design of apoptosis signal-regulating kinase 1 inhibitors: discovering novel structural scaffold.

scientific article

Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor

scientific article published on 11 January 2017

Structure-based discovery of novel flavonol inhibitors of human protein kinase CK2.

scientific article

Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2

scientific article published on 09 January 2011

Treatment of cultured human astrocytes and vascular endothelial cells with protein kinase CK2 inhibitors induces early changes in cell shape and cytoskeleton ⬇️

scientific article published on December 2, 2010

List of works by Volodymyr G. Bdzhola

A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2α Complex Structures

ASK1 pharmacophore model derived from diverse classes of inhibitors.

Ab initio parameterization of YFF1, a universal force field for drug-design applications

Augmenting a training dataset of the generative diffusion model for molecular docking with artificial binding pockets

Design and synthesis of novel protein kinase CK2 inhibitors on the base of 4-aminothieno[2,3-d]pyrimidines.

Design, synthesis and biological evaluation of 2-aminopyrimidinones and their 6-aza-analogs as a new class of CK2 inhibitors.

Design, synthesis and biological evaluation of 5-amino-4-(1H-benzoimidazol-2-yl)-phenyl-1,2-dihydro-pyrrol-3-ones as inhibitors of protein kinase FGFR1.

Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1.

Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors.

Design, synthesis and evaluation of 3-quinoline carboxylic acids as new inhibitors of protein kinase CK2.

Discovery and characterization of synthetic 4'-hydroxyflavones-New CK2 inhibitors from flavone family.

Discovery of potent anti-tuberculosis agents targeting leucyl-tRNA synthetase.

Electrochemical screening of the indole/quinolone derivatives as potential protein kinase CK2 inhibitors

Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2.

Evaluation of 4,5,6,7-tetrahalogeno-1H-isoindole-1,3(2H)-diones as inhibitors of human protein kinase CK2.

Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1)

Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one.

Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one.

Identification of dual-targeted <i>Mycobacterium tuberculosis</i> aminoacyl-tRNA synthetase inhibitors using machine learning

Identification of novel PARP-1 inhibitors by structure-based virtual screening.

Kirchhoff atomic charges fitted to multipole moments: implementation for a virtual screening system.

Novel isoniazid derivative as promising antituberculosis agent

Rational design of apoptosis signal-regulating kinase 1 inhibitors: discovering novel structural scaffold.

Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor

Structure-based discovery of novel flavonol inhibitors of human protein kinase CK2.

Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2

Treatment of cultured human astrocytes and vascular endothelial cells with protein kinase CK2 inhibitors induces early changes in cell shape and cytoskeleton ⬇️