List of works - Peter Hoffmann

14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.

scientific article

2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer

scientific article published in December 2012

A Combined Free-Flow Electrophoresis and DIGE Approach to Compare Proteins in Complex Biological Samples

scientific article published on 01 January 2019

A combined free flow electrophoresis and DIGE approach to compare proteins in complex biological samples

scientific article published on 01 January 2012

A novel optical-fiber based surface plasmon resonance sensing architecture and its application to gastric cancer diagnostics

A sensitive magnetic bead method for the detection and identification of tyrosine phosphorylation in proteins by MALDI-TOF/TOF MS.

scientific article published in June 2009

An external quality assurance trial to assess mass spectrometry protein testing facilities for identifying multiple human peptides

scientific article published on 05 August 2019

An optical fibre protein sensor

Anion−π Interactions of Hexaaryl[3]radialenes

scientific article published on 19 July 2012

Annexin A2 and alpha actinin 4 expression correlates with metastatic potential of primary endometrial cancer.

scientific article

Antibody immobilization within glass microstructured fibers: a route to sensitive and selective biosensors

scientific article published on 01 October 2008

Applications of Mass Spectrometry Imaging to Cancer

scientific article published on 9 January 2017

Balancing sufficiency and impact in reporting standards for mass spectrometry imaging experiments

scientific article published on 01 October 2018

Breast cancer protein StarD10 identified by three-dimensional separation using free-flow electrophoresis, reversed-phase high-performance liquid chromatography, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis

article

Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response.

scientific article published on 3 March 2011

Can collision‐induced negative‐ion fragmentations of [M–H]– anions be used to identify phosphorylation sites in peptides? ⬇️

scientific article published on December 15, 2011

Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae.

scientific article

Chiral capillary electrophoresis as predictor for separation of drug enantiomers in continuous flow zone electrophoresis

scientific article published on 01 October 2000

Classification of MALDI-MS imaging data of tissue microarrays using canonical correlation analysis-based variable selection.

scientific article

Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis.

scientific article published on November 2013

Comparative 2D DIGE analysis of the depleted serum proteome for biomarker discovery

scientific article published on 01 January 2012

Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line

scientific article published on 15 January 2013

Correction to: Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis.

scientific article published on 12 December 2017

Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death

scientific article published on 14 October 2011

Deciphering the Molecular Nature of Ovarian Cancer Biomarker CA125 ⬇️

scientific article published on August 22, 2012

Dephosphorylation of alpha(s)- and beta-caseins and its effect on chaperone activity: a structural and functional investigation

scientific article published on 01 July 2009

Detection and measurement of carbohydrate deficient transferrin in serum using immuno-capture mass spectrometry: Diagnostic applications for annual ryegrass toxicity and corynetoxin exposure ⬇️

scientific article published on October 1, 2011

Detection of quantum-dot labelled proteins using soft glass microstructured optical fibers

scientific article published in December 2007

Differential proteome analysis of the leaves of lead hyperaccumulator, Rhoeo discolor (L. Her.) Hance

scientific article published on 20 November 2020

Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.

scientific article published on 26 September 2011

Dissociation from the oligomeric state is the rate-limiting step in fibril formation by kappa-casein

scientific article

Dynamic Self-Referencing Approach to Whispering Gallery Mode Biosensing and Its Application to Measurement within Undiluted Serum.

scientific article

EZYprep LC-coupled MALDI-TOF/TOF MS: an improved matrix spray application for phosphopeptide characterisation

scientific article

Enrichment of multiphosphorylated peptides by immobilized metal affinity chromatography using Ga(III)- and Fe(III)-complexes

scientific article

Evaluating the efficacy of subcellular fractionation of blast cells using live cell labeling and 2D DIGE

scientific article published on 01 January 2012

Exploring the immunoproteome for ovarian cancer biomarker discovery.

scientific article

Fluorescent polymer coated capillaries as optofluidic refractometric sensors.

scientific article

Fragmentation behavior of glycated peptides derived from D-glucose, D-fructose and D-ribose in tandem mass spectrometry

scientific article

Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress

scientific article published on 3 March 2008

High resolution two-dimensional electrophoresis of native proteins

scientific article published on 16 April 2014

Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer

scientific article published in May 2014

Identification of beer spoilage microorganisms using the MALDI Biotyper platform.

scientific article published on 9 February 2016

Immune derived opioidergic inhibition of viscerosensory afferents is decreased in Irritable Bowel Syndrome patients

scientific article published on 23 July 2014

Increased Phospho-Keratin 8 Isoforms in Colorectal Tumors Associated with EGFR Pathway Activation and Reduced Apoptosis

scientific article published on 31 January 2012

Internal calibrants allow high accuracy peptide matching between MALDI imaging MS and LC-MS/MS ⬇️

scientific article published on May 23, 2012

Isolation and identification of Enterococcus faecalis membrane proteins using membrane shaving, 1D SDS/PAGE, and mass spectrometry.

scientific article published on 19 May 2016

Keratin 5 overexpression is associated with serous ovarian cancer recurrence and chemotherapy resistance.

scientific article

Lymph node metastasis of primary endometrial cancers: Associated proteins revealed by MALDI imaging.

scientific article

MALDI Imaging Mass Spectrometry (MALDI-IMS)-application of spatial proteomics for ovarian cancer classification and diagnosis.

scientific article

MALDI Mass Spectrometry Imaging Reveals Decreased CK5 Levels in Vulvar Squamous Cell Carcinomas Compared to the Precursor Lesion Differentiated Vulvar Intraepithelial Neoplasia.

scientific article

MALDI Mass Spectrometry Imaging of Early- and Late-Stage Serous Ovarian Cancer Tissue Reveals Stage-Specific N-Glycans

scientific article published on 16 August 2019

MALDI imaging mass spectrometry of N-linked glycans on formalin-fixed paraffin-embedded murine kidney.

scientific article

MALDI mass spectrometry imaging of N-glycans on tibial cartilage and subchondral bone proteins in knee osteoarthritis.

scientific article

Mass Spectrometry Analyses of Multicellular Tumour Spheroids.

scientific article published on 11 December 2017

Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) for Monitoring of Drug Response in Primary Cancer Spheroids

scientific article published on 15 October 2019

Matrix-assisted laser desorption/ionization imaging protocol for in situ characterization of tryptic peptide identity and distribution in formalin-fixed tissue.

scientific article

Methionine oxidation enhances κ-casein amyloid fibril formation

scientific article published on 11 April 2012

MicroRNAs are part of the regulatory network that controls EGF induced apoptosis, including elements of the JAK/STAT pathway, in A431 cells

scientific article published on 17 March 2015

Multiplexing of radiative-surface plasmon resonance for the detection of gastric cancer biomarkers in a single optical fiber

N-Glycan matrix-assisted laser desorption/ionization mass spectrometry imaging protocol for formalin-fixed paraffin-embedded tissues.

scientific article

N-glycan MALDI Imaging Mass Spectrometry on Formalin-Fixed Paraffin-Embedded Tissue Enables the Delineation of Ovarian Cancer Tissues.

scientific article

Negative ion fragmentations of deprotonated peptides containing post-translational modifications: diphosphorylated systems containing Ser, Thr and Tyr. A characteristic phosphate/phosphate cyclisation. A joint experimental and theoretical study.

scientific article published on June 2009

Negative ion fragmentations of deprotonated peptides. The unusual case of isoAsp: a joint experimental and theoretical study. Comparison with positive ion cleavages

scientific article published on 01 July 2009

Novel IEF Peptide Fractionation Method Reveals a Detailed Profile of N-Terminal Acetylation in Chemotherapy-Responsive and -Resistant Ovarian Cancer Cells.

scientific article published on 29 August 2016

Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides

scientific article published in September 2009

Phosphorylation of NS5A Serine-235 is essential to hepatitis C virus RNA replication and normal replication compartment formation

scientific article published on 10 February 2016

Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity.

scientific article

Potential mechanisms of the acute coronary syndrome presentation in patients with the coronary slow flow phenomenon - insight from a plasma proteomic approach.

scientific article

Prolonged growth of a clinical Staphylococcus aureus strain selects for a stable small-colony-variant cell type.

scientific article

Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers

scientific article published on 16 October 2019

Proteome Analysis of Drosophila Mutants Identifies a Regulatory Role for 14-3-3ε in Metabolic Pathways

scientific article published on 3 April 2017

Proteomic characterization of mesenchymal stem cell-like populations derived from ovine periodontal ligament, dental pulp, and bone marrow: analysis of differentially expressed proteins.

scientific article

Proteomic comparisons of opaque and transparent variants of Streptococcus pneumoniae by two dimensional-differential gel electrophoresis

scientific article

Proteomic developments in the analysis of formalin-fixed tissue

scientific article

Proteomic responses to gold(iii)-toxicity in the bacterium Cupriavidus metallidurans CH34.

scientific article

Proteomic tracking of serum protein isoforms as screening biomarkers of ovarian cancer.

scientific article published in November 2005

Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer

scientific article

Proteomics of endometrial cancer diagnosis, treatment, and prognosis.

scientific article

Quantitative proteome profiling of CNS-infiltrating autoreactive CD4+ cells reveals selective changes during experimental autoimmune encephalomyelitis.

scientific article published in July 2014

Radiative-SPR platform for the detection of apolipoprotein E for use in medical diagnostics

Radiative-surface plasmon resonance for the detection of apolipoprotein E in medical diagnostics applications.

scientific article

Rapid drug detection in oral samples by porous silicon assisted laser desorption/ionization mass spectrometry.

scientific article published in November 2009

Rapid separation and identification of beer spoilage bacteria by inertial microfluidics and MALDI-TOF mass spectrometry

scientific article published on 17 May 2019

Raw -glycan mass spectrometry imaging data on formalin-fixed mouse kidney

scientific article published on 12 September 2018

Regulation of endothelial cell survival and death by the MAP kinase/ERK kinase kinase 3 - glyceraldehyde-3-phosphate dehydrogenase signaling axis

scientific article published on 02 March 2019

Separation and purification of methadone enantiomers by continuous- and interval-flow electrophoresis

scientific article published on 01 May 1999

State of the art of 2D DIGE.

scientific article

Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1

scientific article published on 2 November 2018

Sub-wavelength fluorescent polymer coatings to convert standard glass capillaries into robust microfluidic refractometric sensors

Surface Plasmon Scattering in Exposed Core Optical Fiber for Enhanced Resolution Refractive Index Sensing.

scientific article

Targeted proteomic analysis of cognitive dysfunction in remitted major depressive disorder: Opportunities of multi-omics approaches towards predictive, preventive, and personalized psychiatry.

scientific article published on 20 February 2018

The Emerging Role of Cytoskeletal Proteins as Reliable Biomarkers

scientific article published on 22 October 2019

The phosphoprotein StarD10 is overexpressed in breast cancer and cooperates with ErbB receptors in cellular transformation

scientific article published on May 2004

The tumor suppressor protein DLC1 is regulated by PKD-mediated GAP domain phosphorylation.

scientific article published on 16 November 2010

The use of MALDI-MSI in the investigation of psychiatric and neurodegenerative disorders: A review.

scientific article

Transforming growth factor-beta-induced protein secreted by peritoneal cells increases the metastatic potential of ovarian cancer cells.

scientific article

Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation.

scientific article published on 21 April 2015

Translating N-Glycan Analytical Applications into Clinical Strategies for Ovarian Cancer

scientific article published on 09 November 2018

Tryptic peptide reference data sets for MALDI imaging mass spectrometry on formalin-fixed ovarian cancer tissues.

scientific article

Tyrosine phosphorylation enrichment and subsequent analysis by MALDI-TOF/TOF MS/MS and LC-ESI-IT-MS/MS.

scientific article

Visualisation in imaging mass spectrometry using the minimum noise fraction transform.

scientific article

p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migration.

scientific article

List of works by Peter Hoffmann

14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.

2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer

A Combined Free-Flow Electrophoresis and DIGE Approach to Compare Proteins in Complex Biological Samples

A combined free flow electrophoresis and DIGE approach to compare proteins in complex biological samples

A novel optical-fiber based surface plasmon resonance sensing architecture and its application to gastric cancer diagnostics

A sensitive magnetic bead method for the detection and identification of tyrosine phosphorylation in proteins by MALDI-TOF/TOF MS.

An external quality assurance trial to assess mass spectrometry protein testing facilities for identifying multiple human peptides

An optical fibre protein sensor

Anion−π Interactions of Hexaaryl[3]radialenes

Annexin A2 and alpha actinin 4 expression correlates with metastatic potential of primary endometrial cancer.

Antibody immobilization within glass microstructured fibers: a route to sensitive and selective biosensors

Applications of Mass Spectrometry Imaging to Cancer

Balancing sufficiency and impact in reporting standards for mass spectrometry imaging experiments

Breast cancer protein StarD10 identified by three-dimensional separation using free-flow electrophoresis, reversed-phase high-performance liquid chromatography, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis

Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response.

Can collision‐induced negative‐ion fragmentations of [M–H]– anions be used to identify phosphorylation sites in peptides? ⬇️

Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae.

Chiral capillary electrophoresis as predictor for separation of drug enantiomers in continuous flow zone electrophoresis

Classification of MALDI-MS imaging data of tissue microarrays using canonical correlation analysis-based variable selection.

Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis.

Comparative 2D DIGE analysis of the depleted serum proteome for biomarker discovery

Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line

Correction to: Combined gene expression and proteomic analysis of EGF induced apoptosis in A431 cells suggests multiple pathways trigger apoptosis.

Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death

Deciphering the Molecular Nature of Ovarian Cancer Biomarker CA125 ⬇️

Dephosphorylation of alpha(s)- and beta-caseins and its effect on chaperone activity: a structural and functional investigation

Detection and measurement of carbohydrate deficient transferrin in serum using immuno-capture mass spectrometry: Diagnostic applications for annual ryegrass toxicity and corynetoxin exposure ⬇️

Detection of quantum-dot labelled proteins using soft glass microstructured optical fibers

Differential proteome analysis of the leaves of lead hyperaccumulator, Rhoeo discolor (L. Her.) Hance

Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.

Dissociation from the oligomeric state is the rate-limiting step in fibril formation by kappa-casein

Dynamic Self-Referencing Approach to Whispering Gallery Mode Biosensing and Its Application to Measurement within Undiluted Serum.

EZYprep LC-coupled MALDI-TOF/TOF MS: an improved matrix spray application for phosphopeptide characterisation

Enrichment of multiphosphorylated peptides by immobilized metal affinity chromatography using Ga(III)- and Fe(III)-complexes

Evaluating the efficacy of subcellular fractionation of blast cells using live cell labeling and 2D DIGE

Exploring the immunoproteome for ovarian cancer biomarker discovery.

Fluorescent polymer coated capillaries as optofluidic refractometric sensors.

Fragmentation behavior of glycated peptides derived from D-glucose, D-fructose and D-ribose in tandem mass spectrometry

Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress

High resolution two-dimensional electrophoresis of native proteins

Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer

Identification of beer spoilage microorganisms using the MALDI Biotyper platform.

Immune derived opioidergic inhibition of viscerosensory afferents is decreased in Irritable Bowel Syndrome patients

Increased Phospho-Keratin 8 Isoforms in Colorectal Tumors Associated with EGFR Pathway Activation and Reduced Apoptosis

Internal calibrants allow high accuracy peptide matching between MALDI imaging MS and LC-MS/MS ⬇️

Isolation and identification of Enterococcus faecalis membrane proteins using membrane shaving, 1D SDS/PAGE, and mass spectrometry.

Keratin 5 overexpression is associated with serous ovarian cancer recurrence and chemotherapy resistance.

Lymph node metastasis of primary endometrial cancers: Associated proteins revealed by MALDI imaging.

MALDI Imaging Mass Spectrometry (MALDI-IMS)-application of spatial proteomics for ovarian cancer classification and diagnosis.

MALDI Mass Spectrometry Imaging Reveals Decreased CK5 Levels in Vulvar Squamous Cell Carcinomas Compared to the Precursor Lesion Differentiated Vulvar Intraepithelial Neoplasia.

MALDI Mass Spectrometry Imaging of Early- and Late-Stage Serous Ovarian Cancer Tissue Reveals Stage-Specific N-Glycans

MALDI imaging mass spectrometry of N-linked glycans on formalin-fixed paraffin-embedded murine kidney.

MALDI mass spectrometry imaging of N-glycans on tibial cartilage and subchondral bone proteins in knee osteoarthritis.

Mass Spectrometry Analyses of Multicellular Tumour Spheroids.

Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) for Monitoring of Drug Response in Primary Cancer Spheroids

Matrix-assisted laser desorption/ionization imaging protocol for in situ characterization of tryptic peptide identity and distribution in formalin-fixed tissue.

Methionine oxidation enhances κ-casein amyloid fibril formation

MicroRNAs are part of the regulatory network that controls EGF induced apoptosis, including elements of the JAK/STAT pathway, in A431 cells

Multiplexing of radiative-surface plasmon resonance for the detection of gastric cancer biomarkers in a single optical fiber

N-Glycan matrix-assisted laser desorption/ionization mass spectrometry imaging protocol for formalin-fixed paraffin-embedded tissues.

N-glycan MALDI Imaging Mass Spectrometry on Formalin-Fixed Paraffin-Embedded Tissue Enables the Delineation of Ovarian Cancer Tissues.

Negative ion fragmentations of deprotonated peptides containing post-translational modifications: diphosphorylated systems containing Ser, Thr and Tyr. A characteristic phosphate/phosphate cyclisation. A joint experimental and theoretical study.

Negative ion fragmentations of deprotonated peptides. The unusual case of isoAsp: a joint experimental and theoretical study. Comparison with positive ion cleavages

Novel IEF Peptide Fractionation Method Reveals a Detailed Profile of N-Terminal Acetylation in Chemotherapy-Responsive and -Resistant Ovarian Cancer Cells.

Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides

Phosphorylation of NS5A Serine-235 is essential to hepatitis C virus RNA replication and normal replication compartment formation

Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity.

Potential mechanisms of the acute coronary syndrome presentation in patients with the coronary slow flow phenomenon - insight from a plasma proteomic approach.

Prolonged growth of a clinical Staphylococcus aureus strain selects for a stable small-colony-variant cell type.

Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers

Proteome Analysis of Drosophila Mutants Identifies a Regulatory Role for 14-3-3ε in Metabolic Pathways

Proteomic characterization of mesenchymal stem cell-like populations derived from ovine periodontal ligament, dental pulp, and bone marrow: analysis of differentially expressed proteins.

Proteomic comparisons of opaque and transparent variants of Streptococcus pneumoniae by two dimensional-differential gel electrophoresis

Proteomic developments in the analysis of formalin-fixed tissue

Proteomic responses to gold(iii)-toxicity in the bacterium Cupriavidus metallidurans CH34.

Proteomic tracking of serum protein isoforms as screening biomarkers of ovarian cancer.

Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer

Proteomics of endometrial cancer diagnosis, treatment, and prognosis.

Quantitative proteome profiling of CNS-infiltrating autoreactive CD4+ cells reveals selective changes during experimental autoimmune encephalomyelitis.