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List of works by Ana M. Tomás

A single-cysteine mutant and chimeras of essential Leishmania Erv can complement the loss of Erv1 but not of Mia40 in yeast.

scientific article published on 23 December 2017

An approach to functional complementation by introduction of large DNA fragments into Trypanosoma cruzi and Leishmania donovani using a cosmid shuttle vector.

scientific article published on May 1994

Antibodies against a Leishmania infantum peroxiredoxin as a possible marker for diagnosis of visceral leishmaniasis and for monitoring the efficacy of treatment

scientific article published on 26 April 2005

Automatic Spectral Unmixing of Leishmania Infection Macrophage Cell Cultures Image

article

Biological Evaluation and Mechanistic Studies of Quinolin-(1<i>H</i>)-Imines as a New Chemotype against Leishmaniasis

scientific article published on 17 June 2021

Calcium and magnesium ions modulate the oligomeric state and function of mitochondrial 2-Cys peroxiredoxins in Leishmania parasites.

scientific article published on 14 March 2017

Canine neutrophils activate effector mechanisms in response to Leishmania infantum

scientific article published on 18 October 2017

Chapter 16. The Redox Metabolism and Oxidative Stress in Leishmania as a Crossroads for the Lethal Effect of Drugs

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of glyoxalase I from Leishmania infantum.

scientific article published on 30 April 2010

Cloning, promoter analysis and expression in response to bacterial exposure of sea bass (Dicentrarchus labrax L.) interleukin-12 p40 and p35 subunits

scientific article published on 29 December 2006

Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum

scientific article

Decreased antimony uptake and overexpression of genes of thiol metabolism are associated with drug resistance in a canine isolate of Leishmania infantum.

scientific article published on 4 June 2016

Detection and separation of overlapping cells based on contour concavity for Leishmania images

scientific article published on 9 April 2014

Development of an automated image analysis protocol for quantification of intracellular forms of Leishmania spp

scientific article published in PLoS ONE

Enlightening the molecular basis of trypanothione specificity in trypanosomatids: mutagenesis of Leishmania infantum glyoxalase II.

scientific article published on 16 August 2011

Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum

scientific article published on 20 May 2014

Heme as a source of iron to Leishmania infantum amastigotes

scientific article published on 01 November 2008

Identification of antibodies to Leishmania silent information regulatory 2 (SIR2) protein homologue during canine natural infections: pathological implications.

scientific article published in April 2003

Immunization with the Leishmania infantum recombinant cyclophilin protein 1 confers partial protection to subsequent parasite infection and generates specific memory T cells.

scientific article

Immunological alterations induced by polyamine derivatives on murine splenocytes and human mononuclear cells

scientific article published in April 2004

Investigation of trypanothione reductase inhibitory activity by 1,3,4-thiadiazolium-2-aminide derivatives and molecular docking studies

scientific article published on 14 January 2012

Iron overload favors the elimination of Leishmania infantum from mouse tissues through interaction with reactive oxygen and nitrogen species

scientific article (publication date: 2013)

Leishmania infantum antigens modulate memory cell subsets of liver resident T lymphocyte

scientific article published on September 2016

Leishmania infantum exerts immunomodulation in canine Kupffer cells reverted by meglumine antimoniate

scientific article published on 2 October 2017

Leishmania infantum: Provision of reducing equivalents to the mitochondrial tryparedoxin/tryparedoxin peroxidase system

scientific article published on 09 September 2008

Leishmania mitochondrial peroxiredoxin plays a crucial peroxidase-unrelated role during infection: insight into its novel chaperone activity

scientific article

LiZIP3 is a cellular zinc transporter that mediates the tightly regulated import of zinc in Leishmania infantum parasites

scientific article published on 11 March 2015

Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum

scientific article

Mitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activity

scientific article

Morphological Characteristics of Schistosoma mansoni PZQ-Resistant and -Susceptible Strains Are Different in Presence of Praziquantel

scientific article published on 26 April 2016

New insights into neutrophil and Leishmania infantum in vitro immune interactions.

scientific article

Ocellatin-PT antimicrobial peptides: High-resolution microscopy studies in antileishmania models and interactions with mimetic membrane systems

scientific article

Peptidomimetic and organometallic derivatives of primaquine active against Leishmania infantum

scientific article published on 27 August 2012

Peroxidases of trypanosomatids

scientific article published on September 2008

Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene

scientific article

Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation.

scientific article published in May 2005

Redox Metabolism in Mitochondria of Trypanosomatids ⬇️

scientific article published on November 15, 2012

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

scientific article published on 13 August 2009

Stage-regulated expression of cruzipain, the major cysteine protease of Trypanosoma cruzi is independent of the level of RNA1.

scientific article published on February 1996

Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection

scientific article

Targeted delivery of paromomycin in murine infectious diseases through association to nano lipid systems

scientific article published on 11 July 2015

Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli.

scientific article

The cytosolic tryparedoxin of Leishmania infantum is essential for parasite survival

scientific article

The glyoxalase pathway in protozoan parasites.

scientific article published on 14 August 2012

The mitochondrial complex I of trypanosomatids--an overview of current knowledge

scientific article published on 25 June 2014

Thiol Peroxidases of Trypanosomatids

Transfection systems for animal models of malaria.

scientific article published in December 1998

Two linked genes of Leishmania infantum encode tryparedoxins localised to cytosol and mitochondrion.

scientific article published in August 2004

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