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List of works by Tuula Salo

(Pro)renin receptor triggers distinct angiotensin II-independent extracellular matrix remodeling and deterioration of cardiac function.

scientific article

3D Culture Histology Cryosectioned Well Insert Technology Preserves the Structural Relationship between Cells and Biomaterials for Time-Lapse Analysis of 3D Cultures

scientific article published on 02 August 2019

<scp>TWIST1</scp> regulates proliferation, migration, and invasion and is a prognostic marker for oral tongue squamous cell carcinoma

scientific article published in 2022

A Proposal to Revise the Histopathologic Grading System of Early Oral Tongue Cancer Incorporating Tumor Budding

scientific article published on 01 May 2019

A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide

scientific article

A novel and selective membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor reduces cancer cell motility and tumor growth

scientific article published on 19 December 2009

A novel human leiomyoma tissue derived matrix for cell culture studies

scientific article

A novel organotypic model mimics the tumor microenvironment

scientific article published on 13 August 2009

A simple novel prognostic model for early stage oral tongue cancer

scientific article published on 11 November 2014

Abstract 4998: In-depth analysis of myoma organotypic model can determine potential markers of oral cancer invasion

scientific article published in 2014

Activin A immunoexpression as predictor of occult lymph node metastasis and overall survival in oral tongue squamous cell carcinoma

scientific article published on 03 April 2014

Activin A triggers angiogenesis via regulation of VEGFA and its overexpression is associated with poor prognosis of oral squamous cell carcinoma

scientific article published on 04 May 2020

Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer

scientific article published on 07 March 2022

Altered expression of hyaluronan, HAS1-2, and HYAL1-2 in oral lichen planus

scientific article published on 25 November 2014

Anti-heparanase aptamers as potential diagnostic and therapeutic agents for oral cancer

scientific article

Arresten, a collagen-derived angiogenesis inhibitor, suppresses invasion of squamous cell carcinoma.

scientific article

Assessment of Tumor-infiltrating Lymphocytes Predicts the Behavior of Early-stage Oral Tongue Cancer

scientific article published on 01 October 2019

Association of MMP-8 with obesity, smoking and insulin resistance

scientific article published on 14 June 2016

Cathepsin K expression is increased in oral lichen planus

scientific article published on 6 May 2016

Cathepsin K is present in invasive oral tongue squamous cell carcinoma in vivo and in vitro

scientific article

Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study

scientific article

Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor

scientific article published on 26 August 2008

Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - β1 (TGF-β1) and potential effects on migration and invasion.

scientific article

Clinicopathologic significance of ROCK2 expression in oral squamous cell carcinomas.

scientific article

Clinicopathological prognostic factors of oral tongue squamous cell carcinoma: a retrospective study of 202 cases

scientific article published on 28 February 2014

Collagen degradation by tumor-associated trypsins.

scientific article published on 28 March 2013

Combination treatment in Chlamydia-triggered reactive arthritis: comment on the article by Carter et al.

scientific article published in January 2011

Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer

scientific article published in Nature Communications

Comparison of supervised machine learning classification techniques in prediction of locoregional recurrences in early oral tongue cancer

scientific article published on 28 December 2019

Compensatory IgM to the Rescue: Patients with Selective IgA Deficiency Have Increased Natural IgM Antibodies to MAA–LDL and No Changes in Oral Microbiota

scientific article

Correction: Human Bone Marrow Mesenchymal Stem Cells Induce Collagen Production and Tongue Cancer Invasion

article by Sirpa Salo et al published 15 November 2013 in PLOS One

Cross-reactive saliva IgA antibodies to oxidized LDL and periodontal pathogens in humans.

scientific article published on 26 May 2017

Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models

scientific article published on 10 May 2017

Cysteine cathepsins in human dentin-pulp complex.

scientific article published in March 2010

Cytotoxicity and effect on protease activity of copolymer extracts containing catechin.

scientific article

Demonstration of 72-kDa and 92-kDa forms of type IV collagenase in human skin: variable expression in various blistering diseases, induction during re-epithelialization, and decrease by topical glucocorticoids

scientific article published on 01 August 1993

Depth of invasion, tumor budding, and worst pattern of invasion: prognostic indicators in early-stage oral tongue cancer

scientific article

Desmoglein 3 - Influence on oral carcinoma cell migration and invasion

scientific article published on 30 June 2018

Distinctive expression pattern of interleukin-17 cytokine family members in colorectal cancer

scientific article published on 25 August 2015

Does securin expression have significance in prognostication of oral tongue cancer? A pilot study

scientific article published on 18 April 2016

Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren's syndrome: a randomized, double-blind, placebo controlled cross-over study.

scientific article

Effects of ionizing radiation and HPSE1 inhibition on the invasion of oral tongue carcinoma cells on human extracellular matrices in vitro

scientific article published on 05 August 2018

Endostatin Inhibits Human Tongue Carcinoma Cell Invasion and Intravasation and Blocks the Activation of Matrix Metalloprotease-2, -9, and -13 ⬇️

scientific article published on April 10, 2003

Endostatin induces proliferation of oral carcinoma cells but its effect on invasion is modified by the tumor microenvironment

scientific article published on 22 June 2015

Epithelial and stromal syndecan‐1 and ‐2 are distinctly expressed in oral‐ and cutaneous squamous cell carcinomas ⬇️

scientific article published on December 21, 2012

Epithelial salivary gland tumors in two distant geographical locations, Finland (Helsinki and Oulu) and Israel (Tel Aviv): a 10-year retrospective comparative study of 2,218 cases

scientific article

Evaluation of the budding and depth of invasion (BD) model in oral tongue cancer biopsies

scientific article published on 2 August 2017

Expression of collagen XVIII and MMP-20 in developing teeth and odontogenic tumors.

scientific article

Expression of matrix metalloproteinase-13 in odontoblast-like cells

scientific article published in October 2013

Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma

scientific article published on 29 September 2010

Expression pattern of claudins 1 and 3-an auxiliary tool in predicting behavior of mucoepidermoid carcinoma of salivary gland origin

scientific article published on 24 December 2010

Extracellular Vesicles Derived From CAFs Induced OSCC Cell Migration, Invasion, and Spreading in Vitro

scholarly article

Extracellular interleukin-17F has a protective effect in oral tongue squamous cell carcinoma

scientific article published on 14 May 2018

Extracellular vesicles derived from cancer-associated fibroblasts induce the migration and invasion of oral squamous cell carcinoma

scientific article published on 13 February 2019

Extracellular vesicles from oral squamous carcinoma cells display pro- and antiangiogenic properties.

scientific article published on 8 September 2017

Fascin promotes migration and invasion and is a prognostic marker for oral squamous cell carcinoma.

scientific article published on 19 August 2017

Fermented Lingonberry Juice Inhibits Oral Tongue Squamous Cell Carcinoma Invasion Similarly to Curcumin

scientific article published on 01 September 2018

Fluctuating roles of matrix metalloproteinase-9 in oral squamous cell carcinoma

scientific article published on 08 January 2013

For early-stage oral tongue cancer, depth of invasion and worst pattern of invasion are the strongest pathological predictors for locoregional recurrence and mortality.

scientific article published on 3 April 2015

Fully Human Tumor-based Matrix in Three-dimensional Spheroid Invasion Assay

scientific article published on 07 May 2019

Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases.

scientific article published on July 2005

Gingival crevicular fluid collagenase-2 (MMP-8) test stick for chair-side monitoring of periodontitis

scientific article published on 01 August 2003

HOXA10 controls proliferation, migration and invasion in oral squamous cell carcinoma.

scientific article published on April 2015

High-serum MMP-8 levels are associated with decreased survival and systemic inflammation in colorectal cancer

scientific article published on 29 May 2018

Histamine H4 receptor signalling in tongue cancer and its potential role in oral carcinogenesis - a short report

scientific article published on 26 June 2017

Human Tumor Tissue-Based 3D In Vitro Invasion Assays.

scientific article published in January 2018

Human bone marrow mesenchymal stem cells induce collagen production and tongue cancer invasion

scientific article

Human chorionic gonadotropin and its free β-subunit stimulate trophoblast invasion independent of LH/hCG receptor.

scientific article published on 17 May 2013

Human mesenchymal stem cell derived osteoblasts degrade organic bone matrix in vitro by matrix metalloproteinases.

scientific article published on September 2005

Human saliva-derived exosomes: comparing methods of isolation

scientific article

Human β-Defensin 2 Expression in Oral Epithelium: Potential Therapeutic Targets in Oral Lichen Planus ⬇️

scientific article published on 10 April 2019

Immune checkpoints indoleamine 2,3-dioxygenase 1 and programmed death-ligand 1 in oral mucosal dysplasia

scientific article published on 20 June 2018

Improved outcomes with oral tongue squamous cell carcinoma in Finland.

scientific article published on 8 May 2017

In vitro humanized 3D microfluidic chip for testing personalized immunotherapeutics for head and neck cancer patients

scientific article published on 26 July 2019

Infection and apoptosis associated with inflammation in periodontitis: An immunohistologic study

scientific article published on 7 July 2017

Inhibitory effects of serum from sepsis patients on epithelial cell migration in vitro: a case control study

scientific article published on 13 January 2017

Insights into the role of components of the tumor microenvironment in oral carcinoma call for new therapeutic approaches.

scientific article published on 22 January 2014

Interleukin-17F Has Anti-Tumor Effects in Oral Tongue Cancer

scientific article published on 11 May 2019

Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma

scientific article published on 12 November 2007

Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis

scientific article published on 28 August 2015

Lymphoepithelial Carcinoma: Two Case Reports and a Systematic Review of Oral and Sinonasal Cases ⬇️

scientific article published on June 23, 2011

MMP-7, MMP-8, and MMP-9 in oral and cutaneous squamous cell carcinomas.

scientific article published on 6 January 2015

MMP8 increases tongue carcinoma cell-cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5

scientific article published on 31 May 2021

Machine learning application for prediction of locoregional recurrences in early oral tongue cancer: a Web-based prognostic tool

scientific article published on 17 August 2019

Macrophages modulate migration and invasion of human tongue squamous cell carcinoma

scientific article

Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene polymorphisms in generalized aggressive periodontitis: gingival crevicular fluid MMP-8 and TIMP-1 levels and outcome of periodontal therapy

scientific article published on 28 November 2013

Matrix metalloproteinase 8 degrades apolipoprotein A-I and reduces its cholesterol efflux capacity

scientific article published on 30 December 2014

Matrix metalloproteinase 9 inhibits the motility of highly aggressive HSC-3 oral squamous cell carcinoma cells

scientific article published on 30 January 2019

Matrix metalloproteinase-8 regulates transforming growth factor-β1 levels in mouse tongue wounds and fibroblasts in vitro.

scientific article

Matrix-metalloproteinase-2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis

scientific article

MiR-455-3p, miR-150 and miR-375 are aberrantly expressed in salivary gland adenoid cystic carcinoma and polymorphous adenocarcinoma

scientific article published on 25 June 2019

MicroRNA and protein profiles in invasive versus non-invasive oral tongue squamous cell carcinoma cells in vitro.

scientific article

Molecular crosstalk between cancer cells and tumor microenvironment components suggests potential targets for new therapeutic approaches in mobile tongue cancer ⬇️

scientific article published on August 16, 2012

Morphological and molecular features of oral fluid-derived exosomes: oral cancer patients versus healthy individuals.

scientific article published on 27 June 2015

Myofibroblasts in oral potentially malignant disorders: Is it related to malignant transformation?

scientific article published on 01 March 2018

Neoplastic extracellular matrix environment promotes cancer invasion in vitro.

scientific article published on 15 April 2016

Neurogenic pulmonary edema in patients with nontraumatic intracerebral hemorrhage: predictors and association with outcome.

scientific article published on 21 February 2013

Niche matters: The comparison between bone marrow stem cells and endometrial stem cells and stromal fibroblasts reveal distinct migration and cytokine profiles in response to inflammatory stimulus.

scientific article

Non-curative treatment of patients with oral tongue squamous-cell carcinoma

scientific article published on 08 May 2019

Nutraceuticals as new treatment approaches for oral cancer: II. Green tea extracts and resveratrol.

scientific article published on 27 March 2013

Oral lichen sclerosus: a systematic review of reported cases and two new cases

scientific article published on 4 January 2018

Organotypic three-dimensional assays based on human leiomyoma-derived matrices.

scientific article published in January 2018

Orthotic insoles do not prevent physical stress-induced low back pain.

scientific article

PCR-based zebrafish model for personalised medicine in head and neck cancer

scientific article published on 22 July 2019

Postradiation Matrix Metalloproteinase-20 Expression and Its Impact on Dental Micromorphology and Radiation-Related Caries.

scientific article published on 31 March 2017

Potential role of nuclear magnetic resonance spectroscopy to identify salivary metabolite alterations in patients with head and neck cancer

Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis

scientific article

Prognostic impact of tumour-stroma ratio in early-stage oral tongue cancers

scientific article published on 10 February 2018

Prognostic significance of the neural invasion in oral squamous cell carcinoma

scientific article published in 2023

Prognostic value of blood and lymphatic vessel markers in tongue cancer: A systematic review

scientific article published on 30 September 2019

Prognostic value of the immunohistochemical detection of cancer-associated fibroblasts in oral cancer: A systematic review and meta-analysis.

scientific article published on 7 August 2017

Prognostic value of tumour budding in oesophageal cancer: a meta-analysis.

scientific article published on 16 July 2015

Proliferative verrucous leukoplakia and its tumor markers: Systematic review and meta-analysis

scientific article published on 11 December 2018

Reduced expression of lipopolysaccharide-induced CXC chemokine in Porphyromonas gingivalis-induced experimental periodontitis in matrix metalloproteinase-8 null mice

scientific article published on 20 August 2010

Reply to 'Comment on 'Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis".

scientific article published on 15 February 2018

Role of RNA binding protein HuR in ductal carcinoma in situ of the breast

scientific article

Role of dentin MMPs in caries progression and bond stability.

scientific article

Role of the high mobility group box 1 signalling axes via the receptor for advanced glycation end-products and toll-like receptor-4 in the immunopathology of oral lichen planus: a potential drug target?

scientific article published on 20 April 2018

Scandinavian Fellowship for Oral Pathology and Oral Medicine: guidelines for oral pathology and oral medicine in the dental curriculum

scientific article published on 24 May 2012

Secretome profiling of oral squamous cell carcinoma-associated fibroblasts reveals organization and disassembly of extracellular matrix and collagen metabolic process signatures.

scientific article published on 13 January 2016

Segment-specific but pathologic laminin isoform profiles in human labial salivary glands of patients with Sjogren's syndrome

scientific article published on 01 December 2004

Selective gelatinase inhibitor peptide is effective in targeting tongue carcinoma cell tumors in vivo.

scientific article published in November 2011

Serum MMP-8 levels increase in colorectal cancer and correlate with disease course and inflammatory properties of primary tumors

scientific article published on 23 October 2011

Short DNA sequences and bacterial DNA induce esophageal, gastric, and colorectal cancer cell invasion.

scientific article

Single nucleotide polymorphism –799C/T in matrix metalloproteinase-8 promoter region in arterial disease

scientific article published on 12 October 2011

Slug is associated with poor survival in squamous cell carcinoma of the lung.

scientific article

Small oral tongue cancers (≤ 4 cm in diameter) with clinically negative neck: from the 7th to the 8th edition of the American Joint Committee on Cancer

scientific article published on 23 July 2018

Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment

scientific article published in March 2006

T(H)1 cytokines are produced in labial salivary glands in Sjögren's syndrome, but also in healthy individuals

scientific article published on 01 January 1999

TLR1-10, NF-κB and p53 expression is increased in oral lichenoid disease

scientific article published on 17 July 2017

TLR4 and TLR9 are induced in oral lichen planus

scientific article published on 05 June 2012

Tenascin-C and fibronectin expression divide early stage tongue cancer into low- and high-risk groups

scientific article published on 17 January 2017

The 8th Edition of the American Joint Committee on Cancer (AJCC8) Staging Manual: any improvement in the prognostication of oral tongue cancer?

scientific article published on 08 January 2019

The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer

scientific article

The Prognostic Value of Immune Checkpoints in Oral Squamous Cell Carcinoma

article

The Role of MMP8 in Cancer: A Systematic Review

scientific article published on 11 September 2019

The expression of myoglobin and ROR2 protein in Dupuytren's disease

scientific article

The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas.

scientific article published on 20 December 2013

The hypoxic tumor microenvironment regulates invasion of aggressive oral carcinoma cells.

scientific article

The interplay of matrix metalloproteinase-8, transforming growth factor-β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma

scientific article published on 3 August 2017

The origin of matrix metalloproteinases in attrited dentine.

scientific article published in December 2013

The prognostic value of histopathological grading systems in oral squamous cell carcinomas.

scientific article published on 24 April 2015

Toll-like receptor 5 (TLR5) expression is a novel predictive marker for recurrence and survival in squamous cell carcinoma of the tongue.

scientific article published on 3 January 2013

Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis ⬇️

scientific article published on April 1, 2013

Toll-like receptor 9 expression in mucoepidermoid salivary gland carcinoma may associate with good prognosis.

scientific article published on 3 February 2014

Toll-like receptor 9 mediates invasion and predicts prognosis in squamous cell carcinoma of the mobile tongue

scientific article

Toll-like receptors -4 and -5 in oral and cutaneous squamous cell carcinomas

scientific article

Toll-like receptors 2, 4, and 9 in primary, metastasized, and recurrent oral tongue squamous cell carcinomas

scientific article published on October 2015

Topical tacrolimus, triamcinolone acetonide, and placebo in oral lichen planus: a pilot randomized controlled trial.

scientific article published on 6 February 2017

Tranexamic acid can inhibit tongue squamous cell carcinoma invasion in vitro.

scientific article published in March 2009

Trypsin-2 enhances carcinoma invasion by processing tight junctions and activating ProMT1-MMP.

scientific article

Trypsins and their role in carcinoma growth

scientific article

Tumor microenvironment and angiogenesis

scientific article published on May 2008

Tumor-Associated Trypsinogen-2 (Trypsinogen-2) Activates Procollagenases (MMP-1, -8, -13) and Stromelysin-1 (MMP-3) and Degrades Type I Collagen ⬇️

scientific article published on May 13, 2003

Tumour budding in head and neck squamous cell carcinoma - a systematic review.

scientific article published on 06 October 2014

Tumour budding in oral squamous cell carcinoma: a meta-analysis.

scientific article

Tumour microenvironments induce expression of urokinase plasminogen activator receptor (uPAR) and concomitant activation of gelatinolytic enzymes

scientific article

Type I and III collagen degradation products in serum predict patient survival in head and neck squamous cell carcinoma

scientific article published on 25 September 2011

Understanding the role of the R-spondin 2-LGR4 system in tongue squamous cell carcinoma progression

scientific article published on 20 May 2019

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