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List of works by Gillian Farnie

A detailed mammosphere assay protocol for the quantification of breast stem cell activity.

scientific article published on 05 June 2012

A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity.

scientific article published on February 2014

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

scientific article

Breast stem cells and cancer

scientific article published on 01 January 2006

Combined inhibition of ErbB1/2 and Notch receptors effectively targets breast ductal carcinoma in situ (DCIS) stem/progenitor cell activity regardless of ErbB2 status

scientific article

Differentiation therapy: targeting breast cancer stem cells to reduce resistance to radiotherapy and chemotherapy.

scientific article published on 18 May 2010

Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9

scientific article published on 25 October 2018

Discovery of an MLLT1/3 YEATS Domain Chemical Probe

scientific article published on 16 November 2018

Focal adhesion kinase and Wnt signaling regulate human ductal carcinoma in situ stem cell activity and response to radiotherapy

scientific article published on February 2015

Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction.

scientific article published on March 2005

Lapatinib inhibits stem/progenitor proliferation in preclinical in vitro models of ductal carcinoma in situ (DCIS).

scientific article

Mammary stem cells and breast cancer--role of Notch signalling.

scientific article published on June 2007

Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways

scientific article published on 01 April 2007

P-cadherin is coexpressed with CD44 and CD49f and mediates stem cell properties in basal-like breast cancer.

scientific article

PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression

scientific article published in December 2017

Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis

scientific article published on 28 September 2016

Primary ductal carcinoma in situ mammosphere formation: importance of the epidermal growth factor and Notch receptor signalling pathways.

scientific article published on 13 May 2008

Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells.

scientific article published on January 2013

Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.

scientific article

Resistance to endocrine therapy: are breast cancer stem cells the culprits?

scientific article published on 28 February 2009

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction based on an isoindolinone scaffold

scientific article

Target Identification Using Chemical Probes

scientific article published on 24 October 2018

The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase.

scientific article

Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model

scientific article published on 11 August 2016

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures.

scientific article published on 26 December 2016