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List of works by Alan Talevi

A successful virtual screening application: prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben

scientific article published in September 2007

An integrated drug development approach applying topological descriptors

scientific article published on September 2012

Anticonvulsant activity of artificial sweeteners: a structural link between sweet-taste receptor T1R3 and brain glutamate receptors

scientific article

Anticonvulsant effect of sodium cyclamate and propylparaben on pentylenetetrazol-induced seizures in zebrafish.

scientific article published on 24 January 2017

Application of Computer-Aided Drug Repurposing in the Search of New Cruzipain Inhibitors: Discovery of Amiodarone and Bromocriptine Inhibitory Effects

scientific article published on 16 August 2013

Application of descriptors based on Lipinski's rules in the QSPR study of aqueous solubilities

scientific article published on 18 March 2007

Application of linear discriminant analysis in the virtual screening of antichagasic drugs through trypanothione reductase inhibition

scientific article published in August 2006

Applications of Nanosystems to Anticancer Drug Therapy (Part I. Nanogels, Nanospheres, Nanocapsules) ⬇️

scientific article published on January 1, 2014

Applications of Nanosystems to Anticancer Drug Therapy (Part II. Dendrimers, Micelles, Lipid-based Nanosystems) ⬇️

scientific article published on January 1, 2014

CNS drug development - lost in translation?

scientific article published on September 2012

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: Physicochemical characterization and in vitro/in vivo evaluation.

scientific article published on 31 March 2018

Cascade Ligand- and Structure-Based Virtual Screening to Identify New Trypanocidal Compounds Inhibiting Putrescine Uptake.

scientific article

Computational approaches for innovative antiepileptic drug discovery

scientific article

Computer-Aided Drug Design: An Overview

scientific article published in January 2018

Computer-Aided Identification of Anticonvulsant Effect of Natural Nonnutritive Sweeteners Stevioside and Rebaudioside A

scientific article

Computer-Aided Recognition of ABC Transporters Substrates and Its Application to the Development of New Drugs for Refractory Epilepsy

scientific article

Computer-guided drug repurposing: identification of trypanocidal activity of clofazimine, benidipine and saquinavir

scientific article published on 12 February 2015

Development and Validation of a Computational Model Ensemble for the Early Detection of BCRP/ABCG2 Substrates during the Drug Design Stage.

scientific article published on 14 July 2017

Development of conformation independent computational models for the early recognition of breast cancer resistance protein substrates.

scientific article published on August 2013

Discovery of anticonvulsant activity of abietic acid through application of linear discriminant analysis

scientific article published on 8 January 2007

Discovery of novel polyamine analogs with anti-protozoal activity by computer guided drug repositioning

scientific article

Editorial (Thematic Issue: Targeted Therapies)

scientific article published on 01 January 2017

High-throughput drug repositioning for the discovery of new treatments for Chagas disease

scientific article published on January 2015

Hybrid Compounds as Anti-infective Agents

scientific article

Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties

scientific article published on 26 July 2019

Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening

scientific article published on 13 February 2018

Identification of levothyroxine antichagasic activity through computer-aided drug repurposing

In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2

scientific article published on 06 August 2019

Interaction of Solid Lipid Nanoparticles and Specific Proteins of the Corona Studied by Surface Plasmon Resonance

article

Is there a relationship between sweet taste and seizures? Anticonvulsant and proconvulsant effects of non-nutritive sweeteners

scientific article

Modern Approaches for the Discovery of Anti-Infectious Drugs for the Treatment of Neglected Diseases.

scientific article

Molecular Topology and Other Promiscuity Determinants as Predictors of Therapeutic Class - A Theoretical Framework to Guide Drug Repositioning?

scientific article published on 01 January 2018

Multi-target pharmacology: possibilities and limitations of the "skeleton key approach" from a medicinal chemist perspective

scientific article

Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option

scientific article published on 16 February 2016

New QSPR study for the prediction of aqueous solubility of drug-like compounds

scientific article published on 29 July 2008

New anticonvulsant candidates prevent P-glycoprotein (P-gp) overexpression in a pharmacoresistant seizure model in mice

scientific article published on 13 August 2019

New similarity-based algorithm and its application to classification of anticonvulsant compounds

scientific article

Novel cruzipain inhibitors for the chemotherapy of chronic Chagas disease

scientific article published on 22 April 2016

Prediction of drug intestinal absorption by new linear and non-linear QSPR.

scientific article published on 9 November 2010

Propylparaben applied after pilocarpine-induced status epilepticus modifies hippocampal excitability and glutamate release in rats

scientific article

Quantitative structure-activity relationship models for compounds with anticonvulsant activity

scientific article published on 10 May 2019

Several new diverse anticonvulsant agents discovered in a virtual screening campaign aimed at novel antiepileptic drugs to treat refractory epilepsy

scientific article published on 06 December 2012

Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action

scientific article

Synthesis of 2-hydrazolyl-4-thiazolidinones based on multicomponent reactions and biological evaluation against Trypanosoma Cruzi

scientific article published on 19 January 2011

Systematic Comparison of the Performance of Different 2D and 3D Ligand-Based Virtual Screening Methodologies to Discover Anticonvulsant Drugs

scientific article published on January 2015

Tailored Multi-Target Agents. Applications and Design Considerations

scientific article published in January 2016

The Importance of Bioactivation in Computer-Guided Drug Repositioning. Why the Parent Drug is Not Always Enough

scientific article published on 16 February 2016

The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies

scientific article published on 01 January 2019

The application of molecular topology for ulcerative colitis drug discovery

scientific article published in November 2017

The new patient and responsible self-medication practices: a critical review

scientific article published on October 2010

Towards responsible, safe self-medication

scientific article published on 01 October 2010

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