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List of works by Joseph Cherian

A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis

scientific article

Characterization of the interaction between Escherichia coli topoisomerase IV E subunit and an ATP competitive inhibitor

scientific article

Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria

scientific article published on 11 August 2018

Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors.

scientific article published on 4 May 2018

NMR structural characterization of the N-terminal active domain of the gyrase B subunit fromPseudomonas aeruginosaand its complex with an inhibitor

article

Pharmacokinetics-pharmacodynamics analysis of bicyclic 4-nitroimidazole analogs in a murine model of tuberculosis

scientific article

Probing cell-division phenotype space and Polo-like kinase function using small molecules

scientific article

Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence

scientific journal article

Small Molecules Targeting the Inactive Form of the Mnk1/2 Kinases.

scientific article published on 14 November 2017

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

scientific article

Structure-activity relationships of antitubercular nitroimidazoles. 3. Exploration of the linker and lipophilic tail of ((s)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-(4-trifluoromethoxybenzyl)amine (6-amino PA-824).

scientific article

Studies toward Unique Mycolactone Macrolides from Mycobacterium ulcerans

scientific article published on 9 March 2009

Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles

scientific article published on 14 November 2011

Synthesis of spirocycles via ring closing metathesis of heterocycles carrying gem-diallyl substituents obtained via ring opening of (halomethyl)cyclopropanes with allyltributyltin

scientific article published on 01 April 2003

Synthesis of the putative structure of eupomatilone-6

scientific article published on 01 February 2004

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