List of works - Dmitri B. Kirpotin

64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer.

scientific article published on 15 March 2017

A gradient-loadable (64)Cu-chelator for quantifying tumor deposition kinetics of nanoliposomal therapeutics by positron emission tomography

scientific article published on 6 September 2014

A novel assay for monitoring internalization of nanocarrier coupled antibodies

scientific article published on 2 October 2006

Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells

scientific article

Anti-HER2 immunoliposomes for targeted therapy of human tumors.

scientific article

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

scientific article published in July 2006

Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models

scientific article published on 05 April 2019

Biological effects of anti-ErbB2 single chain antibodies selected for internalizing function.

scientific article

Building and Characterizing Antibody-Targeted Lipidic Nanotherapeutics

scientific article published in 2012

Canine model of convection-enhanced delivery of liposomes containing CPT-11 monitored with real-time magnetic resonance imaging: laboratory investigation

scientific article published on May 2008

Canine spontaneous glioma: a translational model system for convection-enhanced delivery

scientific article

Cationic liposomes coated with polyethylene glycol as carriers for oligonucleotides.

scientific article published in June 1998

Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine

scientific article published on 30 January 2009

Clinical development of histone deacetylase inhibitors as anticancer agents

scientific article (publication date: 2005)

Comments

scientific article published in January 1997

Companion Diagnostic 64Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer Nanomedicines.

scientific article published on 21 March 2018

Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts

scientific article published on 21 December 2012

Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle

scientific article

Convection-enhanced delivery of Ls-TPT enables an effective, continuous, low-dose chemotherapy against malignant glioma xenograft model

scientific article published on 24 May 2006

Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts

scientific article

Convection-enhanced delivery of targeted quantum dot-immunoliposome hybrid nanoparticles to intracranial brain tumor models

scientific article published on 30 April 2013

Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy

scientific article published in March 2006

Development of a highly stable and targetable nanoliposomal formulation of topotecan

scientific article

Development of ligand-targeted liposomes for cancer therapy

scientific article published in August 2004

Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging

scientific article published in April 2004

Enhanced pharmacodynamic and antitumor properties of a histone deacetylase inhibitor encapsulated in liposomes or ErbB2-targeted immunoliposomes

scientific article

Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo

scientific article

Extensive distribution of liposomes in rodent brains and brain tumors following convection-enhanced delivery.

scientific article

Genospheres: self-assembling nucleic acid-lipid nanoparticles suitable for targeted gene delivery.

scientific article published in April 2006

Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies

scientific article

Impact of single-chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor-expressing tumor cells

scientific article

Improved pharmacokinetics and efficacy of a highly stable nanoliposomal vinorelbine

scientific article published on 23 October 2008

Improving the developability of an anti-EphA2 single-chain variable fragment for nanoparticle targeting

scientific article published on 17 November 2016

Investigation of intravenous delivery of nanoliposomal topotecan for activity against orthotopic glioblastoma xenografts

scientific article published on 27 September 2011

Liposome-based approaches to overcome anticancer drug resistance

scientific article published on October 2003

Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells

scientific article published on January 2004

Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy

scientific article published on March 2006

Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development

scientific article

Pharmacokinetics, tumor accumulation and antitumor activity of nanoliposomal irinotecan following systemic treatment of intracranial tumors.

scientific article

Preclinical manufacture of an anti-HER2 scFv-PEG-DSPE, liposome-inserting conjugate. 1. Gram-scale production and purification

scientific article

Preclinical manufacture of anti-HER2 liposome-inserting, scFv-PEG-lipid conjugate. 2. Conjugate micelle identity, purity, stability, and potency analysis

scientific article published in January 2005

Targeted drug delivery to mesothelioma cells using functionally selected internalizing human single-chain antibodies

scientific article

Targeted tumor cell internalization and imaging of multifunctional quantum dot-conjugated immunoliposomes in vitro and in vivo

scientific article

Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis

scientific article

Tissue affinity of the infusate affects the distribution volume during convection-enhanced delivery into rodent brains: implications for local drug delivery.

scientific article published on 10 February 2006

Tumor targeting using anti-her2 immunoliposomes.

scientific article

List of works by Dmitri B. Kirpotin

64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer.

A gradient-loadable (64)Cu-chelator for quantifying tumor deposition kinetics of nanoliposomal therapeutics by positron emission tomography

A novel assay for monitoring internalization of nanocarrier coupled antibodies

Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells

Anti-HER2 immunoliposomes for targeted therapy of human tumors.

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models

Biological effects of anti-ErbB2 single chain antibodies selected for internalizing function.

Building and Characterizing Antibody-Targeted Lipidic Nanotherapeutics

Canine model of convection-enhanced delivery of liposomes containing CPT-11 monitored with real-time magnetic resonance imaging: laboratory investigation

Canine spontaneous glioma: a translational model system for convection-enhanced delivery

Cationic liposomes coated with polyethylene glycol as carriers for oligonucleotides.

Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine

Clinical development of histone deacetylase inhibitors as anticancer agents

Comments

Companion Diagnostic 64Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer Nanomedicines.

Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts

Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle

Convection-enhanced delivery of Ls-TPT enables an effective, continuous, low-dose chemotherapy against malignant glioma xenograft model

Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts

Convection-enhanced delivery of targeted quantum dot-immunoliposome hybrid nanoparticles to intracranial brain tumor models

Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy

Development of a highly stable and targetable nanoliposomal formulation of topotecan

Development of ligand-targeted liposomes for cancer therapy

Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging

Enhanced pharmacodynamic and antitumor properties of a histone deacetylase inhibitor encapsulated in liposomes or ErbB2-targeted immunoliposomes

Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo

Extensive distribution of liposomes in rodent brains and brain tumors following convection-enhanced delivery.

Genospheres: self-assembling nucleic acid-lipid nanoparticles suitable for targeted gene delivery.

Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies

Impact of single-chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor-expressing tumor cells

Improved pharmacokinetics and efficacy of a highly stable nanoliposomal vinorelbine

Improving the developability of an anti-EphA2 single-chain variable fragment for nanoparticle targeting

Investigation of intravenous delivery of nanoliposomal topotecan for activity against orthotopic glioblastoma xenografts

Liposome-based approaches to overcome anticancer drug resistance

Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells

Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy

Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development

Pharmacokinetics, tumor accumulation and antitumor activity of nanoliposomal irinotecan following systemic treatment of intracranial tumors.

Preclinical manufacture of an anti-HER2 scFv-PEG-DSPE, liposome-inserting conjugate. 1. Gram-scale production and purification

Preclinical manufacture of anti-HER2 liposome-inserting, scFv-PEG-lipid conjugate. 2. Conjugate micelle identity, purity, stability, and potency analysis

Targeted drug delivery to mesothelioma cells using functionally selected internalizing human single-chain antibodies

Targeted tumor cell internalization and imaging of multifunctional quantum dot-conjugated immunoliposomes in vitro and in vivo

Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis

Tissue affinity of the infusate affects the distribution volume during convection-enhanced delivery into rodent brains: implications for local drug delivery.

Tumor targeting using anti-her2 immunoliposomes.