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List of works by Karl E. Griswold

A high throughput MHC II binding assay for quantitative analysis of peptide epitopes.

scientific article

Biodistribution of antibody-targeted and non-targeted iron oxide nanoparticles in a breast cancer mouse model.

scientific article

Bioengineered lysozyme in combination therapies for Pseudomonas aeruginosa lung infections

scientific article

Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate.

scientific article

Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity

scientific article

Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination

scientific article published on 31 August 2020

Crystal Structure of a Charge Engineered Human Lysozyme Having Enhanced Bactericidal Activity

scientific article

Deimmunized Lysostaphin Synergizes with Small-molecule Chemotherapies and Re-sensitizes MRSA to β-Lactam Antibiotics

scientific article published on 14 December 2020

Design and analysis of immune-evading enzymes for ADEPT therapy.

scientific article

Design and engineering of deimmunized biotherapeutics.

scientific article published on 17 June 2016

Engineering Escherichia coli for soluble expression and single step purification of active human lysozyme

scientific article published on 7 December 2012

Enhanced antimicrobial activity of engineered human lysozyme

scientific article

Evolution of highly active enzymes by homology-independent recombination

scientific article

Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa.

scientific article published on 6 July 2018

Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris.

scientific article published on 21 February 2014

Genetically engineered alginate lyase-PEG conjugates exhibit enhanced catalytic function and reduced immunoreactivity

scientific article

Globally deimmunized lysostaphin evades human immune surveillance and enables highly efficacious repeat dosing

scientific article published on 02 September 2020

Molecular sensing with magnetic nanoparticles using magnetic spectroscopy of nanoparticle Brownian motion

scientific article published on 04 July 2013

Optimization algorithms for functional deimmunization of therapeutic proteins

scientific article

Optimization of combinatorial mutagenesis.

scientific article

Optimization of therapeutic proteins to delete T-cell epitopes while maintaining beneficial residue interactions ⬇️

scientific article published on April 1, 2011

Protein fragment swapping: a method for asymmetric, selective site-directed recombination

scientific article

Structure-guided deimmunization of therapeutic proteins

scientific article

The evolution of catalytic efficiency and substrate promiscuity in human theta class 1-1 glutathione transferase

scientific article

The monoclonal myth.

scientific article

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