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List of works by Masayuki Kaneko

4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor

scientific article published on 11 August 2013

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

scientific article

Aberrant neuronal differentiation and inhibition of dendrite outgrowth resulting from endoplasmic reticulum stress.

scientific article published on 10 April 2014

Activation of Ceramidase and Ceramide Kinase by Vanadate via a Tyrosine Kinase–Mediated Pathway ⬇️

scientific article published on November 26, 2010

Activation of OASIS family, ER stress transducers, is dependent on its stabilization ⬇️

scientific article published on June 15, 2012

Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury

scientific article published on 10 February 2018

Calnexin promotes the folding of mutant iduronate 2-sulfatase related to mucopolysaccharidosis type II

scientific article published on 24 April 2019

ER Stress and Disease: Toward Prevention and Treatment.

scientific article published in January 2017

ER Stress-induced Aberrant Neuronal Maturation and Neurodevelopmental Disorders

scientific article published on January 2016

ER signaling in unfolded protein response

scientific article published on 01 December 2003

Effects of Hsp90 inhibitors, geldanamycin and its analog, on ceramide metabolism and cytotoxicity in PC12 cells

scientific article published on 01 January 2012

Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligase implicated in Alzheimer's disease

scientific article

Endoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative disease

scientific article

Evaluation of SLC20A2 mutations that cause idiopathic basal ganglia calcification in Japan

scientific article published on 24 January 2014

Evaluation of synthetic naphthalene derivatives as novel chemical chaperones that mimic 4-phenylbutyric acid.

scientific article

Expression of the ubiquitin ligase HRD1 in neural stem/progenitor cells of the adult mouse brain.

scientific article published on 25 October 2011

Functional evaluation of PDGFB-variants in idiopathic basal ganglia calcification, using patient-derived iPS cells

scientific article published on 05 April 2019

Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation

scientific article published on 3 August 2016

Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation

scientific article

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit

scientific article published on 13 November 2019

IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes

scientific article published on 16 November 2015

Immunohistochemical localization of a ubiquitin ligase HRD1 in murine brain.

scientific article published in May 2008

Induction of murine HRD1 in experimental cerebral ischemia.

scientific article published in November 2004

Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.

scientific article published on 03 March 2014

Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior.

scientific article

Involvement of nuclear factor-kappaB (NF-kappaB) signaling in the expression of inducible nitric oxide synthase (iNOS) gene in rat C6 glioma cells.

scientific article published on August 2000

Involvement of serotonin transporter gene polymorphisms (5-HTT) in impulsive behavior in the japanese population

scientific article

Localization of type-III sodium-dependent phosphate transporter 2 in the mouse brain.

scientific article published on 30 July 2013

Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation

scientific article published on March 2010

Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization

scientific article published on 26 October 2015

Manganese superoxide dismutase is induced by endoplasmic reticulum stress through IRE1-mediated nuclear factor (NF)-kappaB and AP-1 activation.

scientific article published on August 2004

Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Possible Involvement of HRD1, a Novel Molecule Related to Endoplasmic Reticulum Stress, in Alzheimer’s Disease ⬇️

scientific article published on March 2, 2012

Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress.

scientific article published on 8 October 2016

NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene under hypertonic conditions in inner-medullary collecting duct cells

scientific article published in Journal of Biological Chemistry

Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone.

scientific article

Neuronal activity-dependent local activation of dendritic unfolded protein response promotes expression of brain-derived neurotrophic factor in cell soma.

scientific article published on 16 September 2017

Neuroprotection by Endoplasmic Reticulum Stress-Induced HRD1 and Chaperones: Possible Therapeutic Targets for Alzheimer's and Parkinson's Disease

scientific article published on 18 August 2016

Novel functions of ubiquitin ligase HRD1 with transmembrane and proline-rich domains.

scientific article

OASIS modulates hypoxia pathway activity to regulate bone angiogenesis

scientific article published on 12 November 2015

Physiological Roles of Ubiquitin Ligases Related to the Endoplasmic Reticulum

scientific article published on January 2016

Possible Involvement of Ubiquitin Ligase HRD1 Insolubilization in Amyloid .BETA. Generation ⬇️

scientific article published on January 1, 2012

Prediction of response and prognostic factors for Ewing family of tumors in a low incidence population

scientific article published on 9 August 2007

Prediction of response to repeat utilization of anthracycline in recurrent breast cancer patients previously administered anthracycline-containing chemotherapeutic regimens as neoadjuvant or adjuvant chemotherapy

scientific article published on 25 October 2006

Promotion of Cancer Cell Proliferation by Cleaved and Secreted Luminal Domains of ER Stress Transducer BBF2H7

scientific article published on 8 May 2015

Protective Effects of 4-Phenylbutyrate Derivatives on the Neuronal Cell Death and Endoplasmic Reticulum Stress ⬇️

scientific article published on January 1, 2012

Release of arachidonic acid induced by tumor necrosis factor-alpha in the presence of caspase inhibition: evidence for a cytosolic phospholipase A2alpha-independent pathway.

scientific article published on 4 December 2007

Renal medullary tonicity regulates RNF183 expression in the collecting ducts via NFAT5

scientific article published on 01 May 2019

STT3B-Dependent Posttranslational N-Glycosylation as a Surveillance System for Secretory Protein ⬇️

scientific article published on May 17, 2012

Sec16A, a key protein in COPII vesicle formation, regulates the stability and localization of the novel ubiquitin ligase RNF183.

scientific article published on 4 January 2018

Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II

scientific article published on 24 July 2018

Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

scientific article

The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function

scientific article published on 30 May 2020

The androgen-induced protein AIbZIP facilitates proliferation of prostate cancer cells through downregulation of p21 expression.

scientific article published on 17 November 2016

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis

scientific article published on 03 October 2014

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