List of works - Susan E. Waltz

Age-related changes in the epithelial and stromal compartments of the mammary gland in normocalcemic mice lacking the vitamin D3 receptor

scientific article

Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.

scientific article

Cis-acting effects of sequences within 2.4-kb upstream of the human c-myc gene on autonomous plasmid replication in HeLa cells

scientific article published on 01 July 1995

Cis-acting elements in the hepatocyte growth factor-like protein gene regulate kidney and liver-specific expression in mice

scientific article

Conditional deletion of β-catenin in mammary epithelial cells of Ron receptor, Mst1r, overexpressing mice alters mammary tumorigenesis.

scientific article

Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth

scientific article published on 01 December 2006

Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor

scientific article published on October 2003

DNA replication initiates non-randomly at multiple sites near the c-myc gene in HeLa cells

scientific article published on May 1996

Defective transcription elongation in a subset of cancers confers immunotherapy resistance

scientific article published in Nature Communications

Delayed Sequential Co-Delivery of Gefitinib and Doxorubicin for Targeted Combination Chemotherapy.

scientific article published on 27 October 2017

Deletion of the Ron receptor tyrosine kinase domain in mice provides protection from endotoxin-induced acute liver failure.

scientific article published in November 2002

Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice

scientific article published on 6 January 2012

Foxm1 expression in prostate epithelial cells is essential for prostate carcinogenesis.

scientific article published on 17 June 2013

Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury

scientific article published on 15 September 2005

Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models

scientific article published on 12 January 2021

HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.

scientific article

HGFL-mediated RON signaling supports breast cancer stem cell phenotypes via activation of non-canonical β-catenin signaling.

scientific article published on 22 July 2017

Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis

scientific journal article

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model

scientific article published on July 2014

Hepatocyte nuclear factor-4 is responsible for the liver-specific expression of the gene coding for hepatocyte growth factor-like protein

scientific article

Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis

article

Inhibition of ron kinase blocks conversion of micrometastases to overt metastases by boosting antitumor immunity

scientific article published on 23 April 2013

Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation

scientific journal article

Loss of Ron receptor signaling leads to reduced obesity, diabetic phenotypes and hepatic steatosis in response to high-fat diet in mice

scientific article

Loss of vitamin D receptor signaling from the mammary epithelium or adipose tissue alters pubertal glandular development

scientific article published on 19 August 2014

MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients

scientific article published on 27 April 2020

MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages

scientific article published on 09 April 2019

Macrophage-stimulating protein and calcium homeostasis in zebrafish.

scientific article

Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation

scientific article published on 01 December 2006

Maternal diethylhexyl phthalate exposure affects adiposity and insulin tolerance in offspring in a PCNA-dependent manner

scientific article

Met-related receptor tyrosine kinase Ron in tumor growth and metastasis.

scientific article

Multiple initiations in the c-myc replication origin independent of chromosomal location

scientific article published on 01 October 1998

Myeloid-specific expression of Ron receptor kinase promotes prostate tumor growth.

scientific article published on 17 January 2013

Prostate Epithelial RON Signaling Promotes M2 Macrophage Activation to Drive Prostate Tumor Growth and Progression

scientific article published on 21 May 2020

RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis

scientific article published on January 2017

RON-regulated innate immunity is protective in an animal model of multiple sclerosis

scientific article

Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function

scientific journal article

Ron receptor deficient alveolar myeloid cells exacerbate LPS-induced acute lung injury in the murine lung

scientific article

Ron receptor signaling augments mammary tumor formation and metastasis in a murine model of breast cancer

scientific article published in February 2005

Ron receptor signaling is protective against DSS-induced colitis in mice.

scientific article

Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell lines

scientific article

Ron receptor tyrosine kinase negatively regulates TNFalpha production in alveolar macrophages by inhibiting NF-kappaB activity and Adam17 production

scientific article

Ron receptor tyrosine kinase signaling as a therapeutic target

scientific article

Ron receptor tyrosine kinase-dependent hepatic neutrophil recruitment and survival benefit in a murine model of bacterial peritonitis

scientific article

Ron receptor-dependent gene regulation of Kupffer cells during endotoxemia.

scientific article

Ron tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis.

scientific article published in January 2005

Ron-receptor tyrosine kinase in tumorigenesis and metastasis

scientific article

Sequential delivery of erlotinib and doxorubicin for enhanced triple negative Breast cancer treatment using polymeric nanoparticle.

scientific article published in August 2017

Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers.

scientific article published on 26 January 2010

Structure of the Human D1F15S1A Locus: A Chromosome 1 Locus with 97% Identity to the Chromosome 3 Gene Coding for Hepatocyte Growth Factor-like Protein

article

Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth.

scientific article published on January 2011

The BRUCE-ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development

article

The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers

scientific article

The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth

scientific article published on January 2006

The RON receptor tyrosine kinase mediates oncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during pancreatic cancer progression.

scientific article

The Ron receptor promotes prostate tumor growth in the TRAMP mouse model.

scientific article

The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer

scientific article

The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice

scientific article published on November 2009

The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells

scientific article

The Ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor kappaB activation.

scientific article

The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse

scientific article

The receptor tyrosine kinase Ron is expressed in the mouse ovary and regulates inducible nitric oxide synthase levels and ovulation

scientific article published in September 2003

Therapeutic Considerations for Ron Receptor Expression in Prostate Cancer

scientific article published on 30 July 2018

Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member

scientific article

Tumor Cell Autonomous RON Receptor Expression Promotes Prostate Cancer Growth Under Conditions of Androgen Deprivation

scientific article published on 15 August 2018

Vitamin D3-dependent VDR signaling delays ron-mediated breast tumorigenesis through suppression of β-catenin activity.

scientific article

List of works by Susan E. Waltz

Age-related changes in the epithelial and stromal compartments of the mammary gland in normocalcemic mice lacking the vitamin D3 receptor

Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.

Cis-acting effects of sequences within 2.4-kb upstream of the human c-myc gene on autonomous plasmid replication in HeLa cells

Cis-acting elements in the hepatocyte growth factor-like protein gene regulate kidney and liver-specific expression in mice

Conditional deletion of β-catenin in mammary epithelial cells of Ron receptor, Mst1r, overexpressing mice alters mammary tumorigenesis.

Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth

Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor

DNA replication initiates non-randomly at multiple sites near the c-myc gene in HeLa cells

Defective transcription elongation in a subset of cancers confers immunotherapy resistance

Delayed Sequential Co-Delivery of Gefitinib and Doxorubicin for Targeted Combination Chemotherapy.

Deletion of the Ron receptor tyrosine kinase domain in mice provides protection from endotoxin-induced acute liver failure.

Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice

Foxm1 expression in prostate epithelial cells is essential for prostate carcinogenesis.

Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury

Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models

HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.

HGFL-mediated RON signaling supports breast cancer stem cell phenotypes via activation of non-canonical β-catenin signaling.

Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model

Hepatocyte nuclear factor-4 is responsible for the liver-specific expression of the gene coding for hepatocyte growth factor-like protein

Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis

Inhibition of ron kinase blocks conversion of micrometastases to overt metastases by boosting antitumor immunity

Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation

Loss of Ron receptor signaling leads to reduced obesity, diabetic phenotypes and hepatic steatosis in response to high-fat diet in mice

Loss of vitamin D receptor signaling from the mammary epithelium or adipose tissue alters pubertal glandular development

MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients

MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages

Macrophage-stimulating protein and calcium homeostasis in zebrafish.

Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation

Maternal diethylhexyl phthalate exposure affects adiposity and insulin tolerance in offspring in a PCNA-dependent manner

Met-related receptor tyrosine kinase Ron in tumor growth and metastasis.

Multiple initiations in the c-myc replication origin independent of chromosomal location

Myeloid-specific expression of Ron receptor kinase promotes prostate tumor growth.

Prostate Epithelial RON Signaling Promotes M2 Macrophage Activation to Drive Prostate Tumor Growth and Progression

RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis

RON-regulated innate immunity is protective in an animal model of multiple sclerosis

Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function

Ron receptor deficient alveolar myeloid cells exacerbate LPS-induced acute lung injury in the murine lung

Ron receptor signaling augments mammary tumor formation and metastasis in a murine model of breast cancer

Ron receptor signaling is protective against DSS-induced colitis in mice.

Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell lines

Ron receptor tyrosine kinase negatively regulates TNFalpha production in alveolar macrophages by inhibiting NF-kappaB activity and Adam17 production

Ron receptor tyrosine kinase signaling as a therapeutic target

Ron receptor tyrosine kinase-dependent hepatic neutrophil recruitment and survival benefit in a murine model of bacterial peritonitis

Ron receptor-dependent gene regulation of Kupffer cells during endotoxemia.

Ron tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis.

Ron-receptor tyrosine kinase in tumorigenesis and metastasis

Sequential delivery of erlotinib and doxorubicin for enhanced triple negative Breast cancer treatment using polymeric nanoparticle.

Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers.

Structure of the Human D1F15S1A Locus: A Chromosome 1 Locus with 97% Identity to the Chromosome 3 Gene Coding for Hepatocyte Growth Factor-like Protein

Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth.

The BRUCE-ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development

The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers

The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth

The RON receptor tyrosine kinase mediates oncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during pancreatic cancer progression.

The Ron receptor promotes prostate tumor growth in the TRAMP mouse model.

The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer

The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice

The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells

The Ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor kappaB activation.

The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse

The receptor tyrosine kinase Ron is expressed in the mouse ovary and regulates inducible nitric oxide synthase levels and ovulation

Therapeutic Considerations for Ron Receptor Expression in Prostate Cancer

Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member

Tumor Cell Autonomous RON Receptor Expression Promotes Prostate Cancer Growth Under Conditions of Androgen Deprivation

Vitamin D3-dependent VDR signaling delays ron-mediated breast tumorigenesis through suppression of β-catenin activity.