Search filters

List of works by Alfred Ayala

17 beta-Estradiol normalizes immune responses in ovariectomized females after trauma-hemorrhage

scientific article

A Novel Nonanticoagulant Heparin Improves Splenocyte and Peritoneal Macrophage Immune Function after Trauma-Hemorrhage and Resuscitation

scientific article published on 01 July 1995

A Novel Role for Programmed Cell Death Receptor Ligand-1 (PD-L1) in Sepsis-Induced Intestinal Dysfunction

scientific article published on 25 October 2016

A divergent response of innate regulatory T-cells to sepsis in humans: circulating invariant natural killer T-cells are preserved

scientific article published on 20 November 2013

A model of pulmonary atelectasis in rats: activation of alveolar macrophage and cytokine release

scientific article published on March 1993

A novel role for coinhibitory receptors/checkpoint proteins in the immunopathology of sepsis.

scientific article published on 2 February 2018

A novel role for programmed cell death receptor ligand 2 in sepsis-induced hepatic dysfunction

scientific article published on 15 November 2018

ATP-MgCl2 restores renal microcirculation following trauma and severe hemorrhage ⬇️

scientific article published on March 1, 1992

Activation of common antiviral pathways can potentiate inflammatory responses to septic shock

scientific article

Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of Tregs and PD-1.

scientific article

Aggressive fluid resuscitation following intestinal ischemia-reperfusion in immature rats prevents metabolic derangements and down regulates interleukin-6 release

scientific article published on May 1994

An immune perspective on selective decontamination of the digestive tract

scientific article published in June 2002

Another piece of the pathobiological puzzle in the response to trauma

scientific article published on 01 September 2000

Anti-inflammatory mechanisms of sepsis

scientific article published on 09 June 2011

Apoptosis

scientific article published on 01 December 2005

Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets.

scientific article published on January 2008

Apoptosis: A Potential Therapeutic Target in Sepsis and Non-Infectious Systemic Inflammation

B and T lymphocyte attenuator expression on CD4+ T-cells associates with sepsis and subsequent infections in ICU patients

scientific article

BLOCKADE OF ENDOTHELIAL GROWTH FACTOR, ANGIOPOIETIN-2, REDUCES INDICES OF ARDS AND MORTALITY IN MICE RESULTING FROM THE DUAL-INSULTS OF HEMORRHAGIC SHOCK AND SEPSIS.

scientific article

BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction

scientific article published on 29 March 2012

Beneficial Versus Detrimental Effects of Neutrophils Are Determined by the Nature of the Insult

scientific article published on 01 May 2007

Biliary obstruction results in PD-1-dependent liver T cell dysfunction and acute inflammation mediated by Th17 cells and neutrophils

scientific article published on 24 July 2013

Biological significance of elevated TNF levels: In vivo administration of monoclonal antibody against TNF following haemorrhage shock increases the capacity of macrophages to release TNF while restoring immuno-responsiveness

scientific article published on 01 November 1994

Biomarkers for Sepsis: What Is and What Might Be?

scientific article

Blockade of apoptosis as a rational therapeutic strategy for the treatment of sepsis

scientific article published on January 2007

Blockade of endothelial, but not epithelial, cell expression of PD-L1 following severe shock attenuates the development of indirect acute lung injury in mice

scientific article published on 29 January 2020

CD28 homodimer interface mimetic peptide acts as a preventive and therapeutic agent in models of severe bacterial sepsis and gram-negative bacterial peritonitis

scientific article published on 9 October 2014

CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis

scientific article published on 21 January 2009

CD8+ T cells promote inflammation and apoptosis in the liver after sepsis: role of Fas-FasL.

scientific article published in July 2007

CXC CHEMOKINE SUPPRESSION OF POLYMORPHONUCLEAR LEUKOCYTES APOPTOSIS AND PRESERVATION OF FUNCTION IS OXIDATIVE STRESS INDEPENDENT

scientific article published on 01 March 2000

CXCL2 polymorphism in sepsis and acute respiratory distress syndrome: Pathological significance lost in translation*

scientific article published on 01 October 2007

CXCR2 inhibition suppresses hemorrhage-induced priming for acute lung injury in mice

scientific article

Changes in dendritic cell function in the immune response to sepsis. Cell- & tissue-based therapy

scientific article published on July 2007

Chemically induced hypotension increases PGE2 release and depresses macrophage antigen presentation

scientific article published on April 1993

Chloroquine attenuates hemorrhagic shock-induced immunosuppression and decreases susceptibility to sepsis

scientific article published on January 1992

Chloroquine attenuates hemorrhagic shock-induced suppression of Kupffer cell antigen presentation and major histocompatibility complex class II antigen expression through blockade of tumor necrosis factor and prostaglandin release

scientific article published on October 1991

Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model

scientific article published on 14 September 2016

Contribution of anti-inflammatory/immune suppressive processes to the pathology of sepsis

scientific article

Contribution of programmed cell death receptor (PD)-1 to Kupffer cell dysfunction in murine polymicrobial sepsis

scientific article published on 10 June 2016

Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

scholarly article by Marcin F Osuchowski et al published October 2018 in Infection

Cyclooxygenase 2-mediated suppression of macrophage interleukin-12 production after thermal injury ⬇️

scientific article published on February 1, 2002

Cytokine Gene Expression in Splenic Macrophages and Kupffer Cells Following Haemorrhage

article

DEHYDROEPIANDROSTERONE RESTORES IMMUNE FUNCTION FOLLOWING TRAUMA-HAEMORRHAGE BY A DIRECT EFFECT ON T LYMPHOCYTES

scientific article published on 01 June 1999

Decreased monocyte human leukocyte antigen-DR expression after severe burn injury: Correlation with severity and secondary septic shock

scientific article published on 01 August 2007

Deficiency of Bid protein reduces sepsis-induced apoptosis and inflammation, while improving septic survival

scientific article

Deficiency of gammadelta T lymphocytes contributes to mortality and immunosuppression in sepsis

scientific article

Dehydroepiandrosterone: an inexpensive steroid hormone that decreases the mortality due to sepsis following trauma-induced hemorrhage

scientific article published in December 1998

Depressed Osteoblast Activity and Increased Osteocyte Necrosis after Closed Bone Fracture and Hemorrhagic Shock

scientific article published on 01 October 1996

Dextran 70 administration after trauma-hemorrhagic shock does not impair cellular immune functions

scientific article published on 01 December 1994

Differential Alterations in Cardiovascular Responses During the Progression of Polymicrobial Sepsis in the Mouse

article

Differential alterations in plasma IL-6 and TNF levels after trauma and hemorrhage

scientific article

Differential cellular immunolocalization of renal tumour necrosis factor-alpha production during ischaemia versus endotoxaemia

scientific article published on 01 January 2001

Differential effects of hemorrhage on Kupffer cells: decreased antigen presentation despite increased inflammatory cytokine (IL-1, IL-6 and TNF) release

scientific article published on January 1992

Differential effects of macrophage inflammatory chemokine-2 and keratinocyte-derived chemokine on hemorrhage-induced neutrophil priming for lung inflammation: assessment by adoptive cells transfer in mice

scientific article published in April 2003

Diltiazem restores IL-2, IL-3, IL-6, and IFN-γ synthesis and decreases host susceptibility to sepsis following hemorrhage

scientific article published on 01 August 1991

Divergent Effects of Activated Neutrophils on Inflammation, Kupffer Cell/Splenocyte Activation, and Lung Injury Following Blunt Chest Trauma

scientific article published on 01 February 2012

Divergent Effects of Neutrophils on Fas-Induced Pulmonary Inflammation, Apoptosis, and Lung Damage

scientific article published on 11 July 2016

Divergent invariant natural killer T-cell response to sepsis of abdominal vs. non-abdominal origin in human beings

scientific article published on February 2015

Divergent roles of murine neutrophil chemokines in hemorrhage induced priming for acute lung injury

scientific article published in August 2005

Do different rates of fluid resuscitation adversely or beneficially influence immune responses after trauma-hemorrhage?

scientific article published on January 1999

Does Endotoxin Play a Major Role in Inducing the Depression of Macrophage Function During Polymicrobial Sepsis?

scientific article published on 01 November 1995

Does Fas ligand or endotoxin contribute to thymic apoptosis during polymicrobial sepsis?

scientific article published in March 1999

Does endotoxin tolerance prevent the release of inflammatory monokines (interleukin 1, interleukin 6, or tumor necrosis factor) during sepsis?

scientific article published in February 1992

Does hepatocellular injury in sepsis involve apoptosis?

scientific article published in May 1998

Double-hit mouse model of cigarette smoke priming for acute lung injury

scientific article published on 18 November 2016

Editorial board 2010 ⬇️

scientific article published on October 30, 2010

Effect of PD-1: PD-L1 in Invariant Natural Killer T-Cell Emigration and Chemotaxis Following Sepsis

scientific article published on 18 December 2015

Effect of Surgical Trauma on Splenocyte and Peritoneal Macrophage Immune Function

scientific article published on 01 October 1995

Effect of gender and sex hormones on immune responses following shock

scientific article

Effect of naloxone on immune responses after hemorrhagic shock

scientific article

Effects of hydroxyethyl starch after trauma-hemorrhagic shock

scientific article published on 01 May 1995

Effects of prolactin and metoclopramide on macrophage cytokine gene expression in late sepsis

scientific article published in June 1997

Effects of trauma, duration of hypotension, and resuscitation regimen on cellular immunity after hemorrhagic shock

scientific article published on 01 July 1994

Eicosanoids regulate tumor necrosis factor synthesis after hemorrhage in vitro and in vivo

scientific article

Energetics of Lymphocyte "Burnout" in Late Sepsis: Adjuvant Treatment with ATP-MgCl2 Improves Energetics and Decreases Lethality

scientific article published on 01 June 1994

Energetics of defective macrophage antigen presentation after hemorrhage as determined by ultraresolution 31P nuclear magnetic resonance spectrometry: restoration with adenosine triphosphate-MgCl2

scientific article published on 01 August 1992

Enhanced Innate Inflammation Induced by Anti-BTLA Antibody in Dual Insult Model of Hemorrhagic Shock/Sepsis

scientific article published on January 2016

Enhanced Susceptibility to Sepsis After Simple Hemorrhage

scientific article published on 01 January 1990

Enhanced immune responses in females, as opposed to decreased responses in males following haemorrhagic shock and resuscitation

scientific article published in November 1996

Epithelial cell apoptosis and neutrophil recruitment in acute lung injury-a unifying hypothesis? What we have learned from small interfering RNAs

scientific article published on July 2008

Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis

scientific article

FLUTAMIDE

Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern

scientific article published on 20 January 2012

Fas-induced pulmonary apoptosis and inflammation during indirect acute lung injury

scientific article

Fas-ligand mediated apoptosis in severe sepsis and shock

scientific article published on January 2003

Fate and effects of adult bone marrow cells in lungs of normoxic and hyperoxic newborn mice

scientific article

Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis

scientific article

Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males

scientific article published in January 1997

Flutamide: a novel agent for restoring the depressed cell-mediated immunity following soft-tissue trauma and hemorrhagic shock

scientific article published on 01 October 1997

GENDER DIMORPHISM IN TRAUMA-HEMORRHAGE-INDUCED THYMOCYTE APOPTOSIS

scientific article published on 01 October 1999

Genetic disruption of protein kinase Cδ reduces endotoxin-induced lung injury

scientific article

Hemorrhage affects the ability of murine peritoneal macrophages to alkanize intracellular pH in acidic environments.

scientific article published on June 1995

Hemorrhage induces an increase in serum TNF which is not associated with elevated levels of endotoxin

scientific article published on 01 May 1990

Hemorrhage induces enhanced Kupffer cell cytotoxicity while decreasing peritoneal or splenic macrophage capacity. Involvement of cell-associated tumor necrosis factor and reactive nitrogen ⬇️

scientific article published on December 15, 1991

Hepatocellular dysfunction persists during early sepsis despite increased volume of crystalloid resuscitation

scientific article published on March 1, 1992

Hydrodynamic delivery of siRNA in a mouse model of sepsis

scientific article published in January 2008

IL-10 mediation of activation-induced TH1 cell apoptosis and lymphoid dysfunction in polymicrobial sepsis

scientific article published on April 2001

IL-1β STIMULATION INDUCES PARACRINE REGULATION OF PMN FUNCTION AND APOPTOSIS

scientific article

IL-4–induced activation of the Stat6 pathway contributes to the suppression of cell-mediated immunity and death in sepsis

scientific article published on 01 August 2000

IMMUNE DYSFUNCTION FOLLOWING TRAUMA-HAEMORRHAGE: INFLUENCE OF GENDER AND AGE

scientific article published on 01 January 2000

Ibuprofen restores cellular immunity and decreases susceptibility to sepsis following hemorrhage

scientific article published on 01 July 1992

Identification of B7-H1 as a novel mediator of the innate immune/proinflammatory response as well as a possible myeloid cell prognostic biomarker in sepsis

scientific article published on 30 December 2013

Immune Suppression in Polymicrobial Sepsis: Differential Regulation of Th1 and Th2 Responses by p38 MAPK

article

Immune depression in polymicrobial sepsis: The role of necrotic (injured) tissue and endotoxin

scientific article published on 01 August 2000

Immune dysfunction in murine polymicrobial sepsis: mediators, macrophages, lymphocytes and apoptosis.

scientific article published on January 1996

Immunoprotective effect of a calcium channel blocker on macrophage antigen presentation function, major histocompatability class II antigen expression, and interleukin-1 synthesis after hemorrhage

scientific article published on 01 August 1990

Improved antimicrobial host defense in mice following poly-(1,6)-β-D-glucopyranosyl-(1,3)-β-D-glucopyranose glucan treatment by a gender-dependent immune mechanism

scientific article published on 5 October 2011

Improved survival after induction of sepsis by cecal slurry in PD-1 knockout murine neonates

scientific article published on 21 December 2016

In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice

scientific article published on 7 June 2005

In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury

scientific article published on 4 February 2005

Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients

scientific article

Increased inducible apoptosis in CD4+ T lymphocytes during polymicrobial sepsis is mediated by Fas ligand and not endotoxin

scientific article published on 01 May 1999

Increased melatonin levels after hemorrhagic shock in male and female C3H/HeN mice.

scientific article published in June 1996

Increased mucosal B-lymphocyte apoptosis during polymicrobial sepsis is a Fas ligand but not an endotoxin-mediated process ⬇️

scientific article published on February 15, 1998

Inducible macrophage apoptosis following sepsis is mediated by cysteine protease activation and nitric oxide release

scientific article published in July 1997

Inflammatory mechanisms in sepsis: elevated invariant natural killer T-cell numbers in mouse and their modulatory effect on macrophage function

scientific article

Inhibition of CD1d activation suppresses septic mortality: a role for NK-T cells in septic immune dysfunction

scientific article published on 01 November 2003

Inhibition of Fas signaling prevents hepatic injury and improves organ blood flow during sepsis.

scientific article published in August 2001

Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity

scientific article published in September 2003

Insights into the mechanism by which interferon-gamma improves macrophage function following hemorrhage and resuscitation.

scientific article published on April 1993

Insights into the mechanisms of defective antigen presentation after hemorrhage

scientific article published on 01 August 1991

Insights into the role of gammadelta T lymphocytes in the immunopathogenic response to thermal injury

scientific article published on 01 May 2000

Interferon-gamma attenuates hemorrhage-induced suppression of macrophage and splenocyte functions and decreases susceptibility to sepsis

scientific article published on 01 February 1992

Kupffer Cells Protect Liver Sinusoidal Endothelial Cells from Fas-Dependent Apoptosis in Sepsis by Down-Regulating gp130 ⬇️

scientific article published on January 7, 2013

Kupffer cells potentiate liver sinusoidal endothelial cell injury in sepsis by ligating programmed cell death ligand-1.

scientific article published on 13 June 2013

L-Arginine

article

Leukocyte apoptosis and its significance in sepsis and shock

scientific article

Liver myeloid-derived suppressor cells expand in response to liver metastases in mice and inhibit the anti-tumor efficacy of anti-CEA CAR-T

scientific article published on 8 April 2015

Local tissue expression of the cell death ligand, fas ligand, plays a central role in the development of extrapulmonary acute lung injury

scientific article published on August 2011

Loss of signal transducer and activator of transduction 4 or 6 signaling contributes to immune cell morbidity and mortality in sepsis

article

Lymphocyte integrin expression differences between SIRS and sepsis patients.

scientific article

Lymphocytes in the development of lung inflammation: a role for regulatory CD4+ T cells in indirect pulmonary lung injury.

scientific article published on 29 July 2009

Lymphoid apoptosis during sepsis: now that we've found it, what do we do with it?

scientific article published in August 1997

Male sex steroids are responsible for depressing macrophage immune function after trauma-hemorrhage ⬇️

scientific article published on October 1, 1997

Mechanism of Intestinal Mucosal Immune Dysfunction Following Trauma–Hemorrhage: Increased Apoptosis Associated with Elevated Fas Expression in Peyer's Patches

article

Mechanism of Splenic Immunosuppression During Sepsis

scientific article published on 01 May 1997

Mechanism of diltiazem's immunomodulatory effects after hemorrhage and resuscitation

scientific article published on August 1993

Mechanism of enhanced susceptibility to sepsis following hemorrhage. Interleukin-10 suppression of T-cell response is mediated by eicosanoid-induced interleukin-4 release.

scientific article published in November 1994

Mechanism of immune dysfunction in sepsis: inducible nitric oxide-meditated alterations in p38 MAPK activation

scientific article

Mechanism of immunosuppression following hemorrhage: Defective antigen presentation by macrophages

scientific article published on 01 June 1989

Mechanism of immunosuppression in males following trauma-hemorrhage. Critical role of testosterone

scientific article published in November 1996

Mechanism of the beneficial effects of ATP-MgCl2 following trauma-hemorrhage and resuscitation: Downregulation of inflammatory cytokine (TNF, IL-6) release

scientific article published on 01 April 1992

Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation

scientific article published on 01 August 1992

Mechanisms of immune resolution

scientific article

Mechanisms of indirect acute lung injury: a novel role for the coinhibitory receptor, programmed death-1.

scientific article published on January 2012

Melatonin Administration Attenuates Depressed Immune Functions after Trauma-Hemorrhage

scientific article published on 01 June 1996

Melatonin Administration Following Hemorrhagic Shock Decreases Mortality from Subsequent Septic Challenge

scientific article published on 01 October 1996

Metoclopramide

scientific article published on 01 January 1998

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

scholarly article by Marcin F. Osuchowski et al published 14 August 2018 in Infection

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

Modulation of Macrophage Membrane Phospholipids by n-3 Polyunsaturated Fatty Acids Increases Interleukin 1 Release and Prevents Suppression of Cellular Immunity Following Hemorrhagic Shock

scientific article published on 01 January 1993

MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis

scientific article

NF-kappaB activation has tissue-specific effects on immune cell apoptosis during polymicrobial sepsis

scientific article published in October 2002

Neither Fas Ligand nor Endotoxin Is Responsible for Inducible Peritoneal Phagocyte Apoptosis during Sepsis/Peritonitis

scientific article published on 01 June 2000

Neutrophil-endothelial interactions mediate angiopoietin-2-associated pulmonary endothelial cell dysfunction in indirect acute lung injury in mice

scientific article published on January 2014

Neutrophils Regulate Their Own Apoptosis via Preservation of CXC Receptors

scientific article published on 01 May 2000

No good deed goes unpunished!

scientific article

Novel Role for PD-1:PD-L1 as Mediator of Pulmonary Vascular Endothelial Cell Functions in Pathogenesis of Indirect ARDS in Mice

On-pump coronary artery bypass surgery activates human myocardial NF-κB and increases TNF-α in the heart

scientific article published on 01 June 2003

PAD4 Deficiency Leads to Decreased Organ Dysfunction and Improved Survival in a Dual Insult Model of Hemorrhagic Shock and Sepsis.

scientific article published on 26 January 2018

PAF-Antagonist Administration after Hemorrhage-Resuscitation Prevents Splenocyte Immunodepression

scientific article published on 01 September 1995

PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

scholarly article

Paracrine suppression of apoptosis by cytokine-stimulated neutrophils involves divergent regulation of NF-kappaB, Bcl-X(L), and Bak.

scientific article published in January 2002

Pathogenesis of indirect (secondary) acute lung injury

scientific article

Pathological aspects of apoptosis in severe sepsis and shock?

scientific article

Pentoxifylline Attenuates Oxygen-Induced Lung Injury

scientific article published on 01 June 1994

Pepducins: an effective means to inhibit GPCR signaling by neutrophils

scientific article published on 21 September 2005

Phospho-SXXE/D motif mediated TNF receptor 1-TRADD death domain complex formation for T cell activation and migration.

scientific article

Plasmacytoid dendritic cells control lung inflammation and monocyte recruitment in indirect acute lung injury in mice

scientific article

Polymicrobial Sepsis but Not Low-Dose Endotoxin Infusion Causes Decreased Splenocyte IL-2/IFN-γ Release While Increasing IL-4/IL-10 Production

scientific article published on 01 June 1994

Polymicrobial sepsis enhances clearance of apoptotic immune cells by splenic macrophages

scientific article

Polymicrobial sepsis induces divergent effects on splenic and peritoneal dendritic cell function in mice

scientific article

Polymicrobial sepsis selectively activates peritoneal but not alveolar macrophages to release inflammatory mediators (interleukins-1 and -6 and tumor necrosis factor)

scientific article published on 01 March 1992

Premise for Standardized Sepsis Models

scientific article published on 01 January 2019

Program Cell Death Receptor-1-Mediated Invariant Natural Killer T-Cell Control of Peritoneal Macrophage Modulates Survival in Neonatal Sepsis

scientific article published on 20 November 2017

Programmed Death 1 Expression as a Marker for Immune and Physiological Dysfunction in the Critically Ill Surgical Patient

scientific article published on 01 August 2012

Programmed cell death receptor ligand 1 modulates the regulatory T cells' capacity to repress shock/sepsis-induced indirect acute lung injury by recruiting phosphatase SRC homology region 2 domain-containing phosphatase 1.

scientific article

Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients.

scientific article published on 21 March 2011

Prolactin administration following hemorrhagic shock improves macrophage cytokine release capacity and decreases mortality from subsequent sepsis

scientific article published on 01 December 1996

Prolactin inhibits the increased cytokine gene expression in Kupffer cells following haemorrhage

article

Prolactin: A Novel and Safe Immunomodulating Hormone for the Treatment of Immunodepression Following Severe Hemorrhage

scientific article published on 01 June 1996

Prolonged Immunodepression after Trauma and Hemorrhagic Shock

scientific article published on 01 February 1998

Pulmonary contusion causes impairment of macrophage and lymphocyte immune functions and increases mortality associated with a subsequent septic challenge

scientific article published in June 2005

Putative mechanism of hemorrhage-induced leukocyte hyporesponsiveness: induction of suppressor of cytokine signaling-3.

scientific article published on April 2004

RNA interference as a potential therapeutic treatment for inflammation associated lung injury.

scientific article published on 25 February 2008

Recombinant human activated protein C inhibits integrin-mediated neutrophil migration

scientific article

Regulation of Trypanosoma cruzi infectivity by alpha- and beta-adrenergic agonists: desensitization produced by prolonged treatments or increasing agonist concentrations

scientific article published on 01 June 1990

Regulatory T cell populations in sepsis and trauma.

scientific article published on 03 October 2007

Role of Activated Neutrophils in Chest Trauma–Induced Septic Acute Lung Injury

scientific article published on 01 July 2012

Role of Interleukin 6 and Transforming Growth Factor–β in the Induction of Depressed Splenocyte Responses Following Sepsis

article

Role of Programmed Cell Death in the Immunopathogenesis of Sepsis

scientific article published on January 2007

Role of alveolar macrophage and migrating neutrophils in hemorrhage-induced priming for ALI subsequent to septic challenge

scientific article published on 09 September 2005

Role of protein kinase C in cyclic AMP-mediated suppression of T-lymphocyte activation following burn injury

scientific article published on 01 September 1999

SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model

scientific article published on 21 September 2020

SOCS-1 is a central mediator of steroid-increased thymocyte apoptosis and decreased survival following sepsis

scientific article published on 01 July 2007

Sepsis induces an early increased spontaneous release of hepatocellular stimulatory factor (interleukin-6) by Kupffer cells in both endotoxin tolerant and intolerant mice

scientific article published on 01 June 1992

Sepsis induces increased apoptosis in lamina propria mononuclear cells which is associated with altered cytokine gene expression

scientific article published in June 1998

Sepsis-induced changes in macrophage co-stimulatory molecule expression: CD86 as a regulator of anti-inflammatory IL-10 response

scientific article

Sepsis-induced potentiation of peritoneal macrophage migration is mitigated by programmed cell death receptor-1 gene deficiency.

scientific article

Severe depression of host immune functions following closed-bone fracture, soft-tissue trauma, and hemorrhagic shock

scientific article published on August 1998

Sex-specific p38 MAP kinase activation following trauma-hemorrhage: involvement of testosterone and estradiol

scientific article

Shock and hemorrhage: an overview of animal models

scientific article

Shock-induced neutrophil mediated priming for acute lung injury in mice: divergent effects of TLR-4 and TLR-4/FasL deficiency

scientific article published on December 2002

Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis

scientific article

Soluble programmed cell death receptor-1 (sPD-1): a potential biomarker with anti-inflammatory properties in human and experimental acute respiratory distress syndrome (ARDS).

scientific article

Splenic Immune Suppression in Sepsis: A Role for IL-10-Induced Changes in P38 MAPK Signaling

scientific article published on 01 May 1999

Suppression of PMN apoptosis by hypoxia is dependent on Mcl-1 and MAPK activity

scientific article published on 01 August 2000

TAT-SNAP-23 treatment inhibits the priming of neutrophil functions contributing to shock and/or sepsis-induced extra-pulmonary acute lung injury

scientific article

THE INDUCTION OF ACCELERATED THYMIC PROGRAMMED CELL DEATH DURING POLYMICROBIAL SEPSIS

article by Alfred Ayala et al published April 1995 in Shock

TNFα-INDUCED SUPPRESSION OF PMN APOPTOSIS IS MEDIATED THROUGH INTERLEUKIN-8 PRODUCTION

scientific article published on 01 September 2000

TRAUMA-HEMORRHAGE CAUSES PROLONGED DEPRESSION IN CELLULAR IMMUNITY

scientific article published on 01 August 1995

Testosterone and estrogen differently effect Th1 and Th2 cytokine release following trauma-haemorrhage.

scientific article published in October 2001

Testosterone and/or low estradiol: normally required but harmful immunologically for males after trauma-hemorrhage

scientific article published in January 1998

The Complex Pattern of Cytokines in Sepsis Association Between Prostaglandins, Cachectin, and Interleukins

scientific article published on 01 August 1991

The Role of Neutrophils in Producing Hepatocellular Dysfunction during the Hyperdynamic Stage of Sepsis in Rats

article

The acute immunological response to blood transfusion is influenced by polymicrobial sepsis

scientific article

The apoptotic pathway as a therapeutic target in sepsis

scientific article published on April 2007

The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients

scientific article published on December 2008

The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsis

scientific article published on March 2007

The contribution of soft-tissue trauma and/or bone fracture to depressed immunity following hemorrhagic shock in an experimental setting

scientific article published on 01 January 1998

The dual functions of receptor interacting protein 1 in fas-induced hepatocyte death during sepsis

scientific article

The geriatric cytokine response to trauma: time to consider a new threshold

scientific article published on December 2014

The induction of accelerated thymic programmed cell death during polymicrobial sepsis: control by corticosteroids but not tumor necrosis factor

scientific article published in April 1995

The launch of the international journal of clinical and experimental medicine

scientific article

The new normal: immunomodulatory agents against sepsis immune suppression

scientific article published on 30 January 2014

The role and regulation of apoptosis in sepsis

scientific article

The role and source of tumor necrosis factor-α in hemorrhage-induced priming for septic lung injury.

scientific article

The role of bacterial translocation on Kupffer cell immune function following hemorrhage.

scientific article published on January 1995

The role of hepatic invariant NKT cells in systemic/local inflammation and mortality during polymicrobial septic shock

scientific article published on February 2009

Therapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury

scientific article

Trauma-hemorrhage delays wound healing potentially by increasing pro-inflammatory cytokines at the wound site

scientific article published on 01 August 1999

Trauma-hemorrhage delays wound healing potentially by increasing pro-inflammatory cytokines at the wound site

article

Trauma-induced suppression of antigen presentation and expression of major histocompatibility class II antigen complex in leukocytes

scientific article published in February 1996

Trauma–Hemorrhage Induces Increased Thymic Apoptosis While Decreasing IL-3 Release and Increasing GM-CSF

article

Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis

scientific article

Tumor necrosis factor-alpha produces hepatocellular dysfunction despite normal cardiac output and hepatic microcirculation

scientific article published on July 1993

Tumor necrosis factor-alpha-stimulated polymorphonuclear leukocytes suppress migration and bactericidal activity of polymorphonuclear leukocytes in a paracrine manner

scientific article

What is the role of interleukin 10 in polymicrobial sepsis: Anti-inflammatory agent or immunosuppressant?

article by Grace Y. Song et al published August 1999 in Surgery

What is the role of interleukin 10 in polymicrobial sepsis: anti-inflammatory agent or immunosuppressant?

scientific article published on 01 August 1999

What’s New in Shock, March 2012?

scientific article published on 01 March 2012

l-Arginine attenuates trauma-hemorrhage-induced liver injury

scientific article published on 01 September 2000

p38 MAPK mediates renal tubular cell TNF-alpha production and TNF-alpha-dependent apoptosis during simulated ischemia

scientific article

Paulina is supported by:

About Paulina

Help