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List of works by Anne Spurkland

A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

scientific article published on 01 December 2009

A follow-up study of Nordic multiple sclerosis candidate gene regions

scientific article

A genome-wide screen for linkage in Nordic sib-pairs with multiple sclerosis

article

A high-density screen for linkage in multiple sclerosis

scientific article

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis

scientific article published on 4 November 2009

A simple and efficient workflow for generation of knock-in mutations in Jurkat T cells using CRISPR/Cas9

scientific article published on 14 January 2020

A strong impact of matching for a limited number of HLA-DR antigens on graft survival and rejection episodes: a single-center study of first cadaveric kidneys to nonsensitized recipients

scientific article published on 01 August 1998

Adaptor proteins: Flexible and dynamic modulators of immune cell signaling

scientific article published on 31 July 2020

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

scientific article published on 29 September 2013

Association of matrix metalloproteinase-1 and -3 promoter polymorphisms with clinical subsets of Norwegian primary sclerosing cholangitis patients

scientific article published on 01 August 2004

Association of the tumour necrosis factor alpha -308 but not the interleukin 10 -627 promoter polymorphism with genetic susceptibility to primary sclerosing cholangitis.

scientific article

B-cell tolerance to the B-cell receptor variable regions

scientific article published on 19 July 2013

CTLA4 promoter and exon 1 dimorphisms in multiple sclerosis

Cholangiocarcinoma in primary sclerosing cholangitis: K-ras mutations and Tp53 dysfunction are implicated in the neoplastic development

scientific article published on 01 March 2000

Class II HLA interactions modulate genetic risk for multiple sclerosis

scientific article published on 07 September 2015

Coding region polymorphisms in T cell signal transduction genes. Prevalence and association to development of multiple sclerosis

scientific article published on 09 June 2006

Concordance for disease course and age of onset in Scandinavian multiple sclerosis coaffected sib pairs

scientific article published on 01 February 2004

Coordinated expression of DNAM-1 and LFA-1 in educated NK cells

scientific article published on 30 March 2015

Demonstration of identical expanded clones within both CD8+CD28+ and CD8+CD28- T cell subsets in HIV type 1-infected individuals

scientific article published in May 1998

Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (α1*0501, (β1*02) or the HLA-DQ (α1*03, (β1*0302) heterodimers

scientific article published on 01 January 1997

Distribution of HLA class II alleles among Norwegian Caucasians

scientific article published on 01 December 1990

Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus

scientific article published on 01 March 1991

Does genomic HLA-DR matching further enhance the effects of serologic DR matching in clinical renal transplantation?

scientific article published on 01 June 1994

Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus

scientific article published on 23 December 2010

Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level

scientific article published on 26 December 2007

Expression of the T cell-specific adapter protein in human tissues

scientific article published in September 2014

Expression of the T-cell-specific adapter protein in oral epithelium

scientific article

Features of autoimmune hepatitis in primary sclerosing cholangitis: an evaluation of 114 primary sclerosing cholangitis patients according to a scoring system for the diagnosis of autoimmune hepatitis

scientific article

Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis.

scientific article published in March 2004

Genetic and molecular approaches to the immunopathogenesis of multiple sclerosis: an update

scientific article published on June 2009

Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Genetics in multiple sclerosis: past and future perspectives.

scientific article published on January 2007

Genomic HLA-DRB1 matching further improves clinical course after renal transplantation

scientific article published on 01 February 1995

HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations

scientific article (publication date: May 1999)

HLA matching of unrelated bone marrow transplant pairs: direct sequencing of in vitro amplified HLA-DRB1 and -DQB1 genes using magnetic beads as solid support

scientific article published on 01 March 1993

HLA profile of three ethnic groups living in the North-Western region of Russia

scientific article (publication date: 2002)

HLA-DQ antigens and DQ beta amino acid 57 of Japanese patients with insulin-dependent diabetes mellitus: detection of a DRw8DQw8 haplotype

scientific article

HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop multiple sclerosis

scientific article published on January 1991

HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7.

scientific article published in November 1992

HLA-DR-DQ haplotype frequencies in a Norwegian population

scientific article published on February 1, 1992

HLA-DRB1, -DQA1, -DQB1, -DPA1 and -DPB1 genes in Japanese multiple sclerosis patients

scientific article published in April 1991

Heterogeneity of T cells specific for a particular peptide/HLA-DQ complex

scientific article published in January 1994

Hla class ii alleles and heterogeneity of juvenile rheumatoid arthritis.drb1*0101 may define a novel subset of the disease

scientific article published on 01 April 1993

Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex

scientific article published on 11 September 2004

In vitro analysis of antigen induced T cell-monocyte conjugates by imaging flow cytometry

scientific article published on 04 July 2018

Isolation and characterization of a human pseudogene for the regulatory subunit RI alpha of cAMP-dependent protein kinases and its sublocalization on chromosome 1.

scientific article published on March 1993

K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location

scientific article

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis

scientific article published in June 2009

Lack of association with the CD28/CTLA4/ICOS gene region among Norwegian multiple sclerosis patients

article

Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis

scientific article published on June 2010

Linkage analysis suggests a region of importance for multiple sclerosis in 3p14-13

scientific article published on 01 December 2001

Linkage disequilibrium between DPA1 and DPB1 alleles among Norwegian Caucasoids and Japanese

scientific article published on 01 July 1992

Linkage disequilibrium screening for multiple sclerosis implicates JAG1 and POU2AF1 as susceptibility genes in Europeans

scientific article

Low frequency and rare coding variation contributes to multiple sclerosis risk

Mapping genes and pathways in autoimmune disease

scientific article

Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln-->Leu61).

scientific article published in November 1992

Microchimerism in immune competent patients related to the leukocyte content of transfused red blood cell concentrates

scientific article published in December 2004

Modulation of Lck function through multisite docking to T cell-specific adapter protein

scientific article

Molecular analysis of the complementarity determining region 3 of the human T cell receptor beta chain. Establishment of a reference panel of CDR3 lengths from phytohaemagglutinin activated lymphocytes

scientific article published on 01 March 1999

Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites

scientific article

Molecular genetic studies of natives on Easter Island: evidence of an early European and Amerindian contribution to the Polynesian gene pool

scientific article (publication date: 2007)

Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells

scientific article published on 23 July 2015

Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus

article

Myasthenia gravis patients with thymus hyperplasia and myasthenia gravis patients with thymoma display different HLA associations

scientific article published on 01 February 1991

New gene map for multiple sclerosis

scientific article

No association of multiple sclerosis to alleles at the TAP2 locus

scientific article published on 01 April 1994

No linkage or association of the nitric oxide synthase genes to multiple sclerosis

scientific article published on 01 September 2001

No major effect of the CD28/CTLA4/ICOS gene region on susceptibility to primary sclerosing cholangitis.

scientific article

Novel HLA-DR2 and -DR3 haplotypes among Norwegian Caucasians

scientific article published on 01 April 1991

Parent of origin in multiple sclerosis: understanding inheritance in complex neurologic diseases

scientific article published on 01 September 2008

Particular HLA-DQ alpha beta heterodimer associated with IDDM susceptibility in both DR4-DQw4 Japanese and DR4-DQw8/DRw8-DQw4 whites

scientific article published on June 1991

Physical separation of HLA-A alleles by denaturing high-performance liquid chromatography.

scientific article

Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd

scientific article published in Scientific Reports

Primary sclerosing cholangitis is associated to an extended B8-DR3 haplotype including particular MICA and MICB alleles

scientific article published on 01 October 2001

Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes

scientific article

Reduced MCMV Δm157 viral clearance in the absence of TSAd

scientific article

Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor

scientific article published on 18 March 2009

Report from the HLA class II typing by PCR-SSP Multicentre Study ⬇️

scientific article published on 01 June 1997

Retinoic acid enhances the levels of IL-10 in TLR-stimulated B cells from patients with relapsing-remitting multiple sclerosis

scientific article published on 24 November 2014

Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy

scientific article published on January 2015

Rheumatoid arthritis may be primarily associated with HLA-DR4 molecules sharing a particular sequence at residues 67-74.

scientific article

SH2D2A modulates T cell mediated protection to a B cell derived tumor in transgenic mice

scientific article

Solubility of recombinant Src homology 2 domains expressed in E. coli can be predicted by TANGO

scientific article published on 14 January 2014

Strict adherence to a common rank order of T-cell receptor V beta usage in human leucocyte antigen disparate individuals

scientific article published on 01 August 1996

Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7

scientific article

Studies of the T-cell receptors of T cells recognizing the same HLA molecule

scientific article published on 01 February 1993

Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles

scientific article published on 01 November 1990

T cell epitopes encompassing the mutational hot spot position 61 of p21 ras. Promiscuity in ras peptide binding to HLA.

scientific article published in February 1994

T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells

scientific article

T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells

scientific article published on 11 July 2015

T cell-specific adapter protein inhibits T cell activation by modulating Lck activity

scientific article published on 01 September 2000

The C terminus of T cell-specific adapter protein (TSAd) is necessary for TSAd-mediated inhibition of Lck activity

scientific article

The HLA-DR3,DQ2 heterozygous genotype is associated with an accelerated progression of primary sclerosing cholangitis

scientific article (publication date: August 2001)

The HLA‐DQ(α1*0102, β1*0602) heterodimer may confer susceptibility to multiple sclerosis in the absence of the HLA‐DR(α1*01, β1*1501) heterodimer ⬇️

scientific article published on 01 July 1997

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

scholarly article published 13 July 2017

The SH2D2A gene and susceptibility to multiple sclerosis

scientific article published on 12 June 2008

The SH2D2A gene encoding the T-cell-specific adapter protein (TSAd) is localized centromeric to the CD1 gene cluster on human Chromosome 1.

scientific article

The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein

scientific article published on 04 September 2019

The T cell receptor repertoire of CD8+CD28- T lymphocytes is dominated by expanded clones that persist over time

scientific article published on 01 August 1999

The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis.

scientific article

The amino acid at position 57 of the HLA-DQ beta chain and susceptibility to develop insulin-dependent diabetes mellitus

scientific article

The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

scientific article published on 19 July 2016

The impact of HLA-A and -DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients

scientific article published on 01 August 2007

The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.

scientific article published on 9 December 2014

The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells.

scientific article

The use of modified primer competitors to enhance yields and specificity of HLA class I amplification by polymerase chain reaction (PCR).

scientific article

Transcriptional activation of the SH2D2A gene is dependent on a cyclic adenosine 5'-monophosphate-responsive element in the proximal SH2D2A promoter

scientific article published on May 2004

Tumour necrosis factor receptor superfamily member 6 gene mutation detection by denaturing high-performance liquid chromatography

scientific article

Two genome-wide linkage disequilibrium screens in Scandinavian multiple sclerosis patients

scientific article published in October 2003

VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis

scientific article

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.

scientific article

X chromosome inactivation in females with multiple sclerosis

scientific article published on 26 October 2007

[Genetic variation--useful information for everybody?]

scientific article published on 01 March 2002

cDNA cloning of a rat orthologue of SH2D2A encoding T-cell-specific adaptor protein (TSAd): expression in T and NK cells

scientific journal article

p21-ras-peptide-specific T-cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly-->Asp).

scientific article published in January 1994

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