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List of works by Hai-Hui Xue

Bystander responses impact accurate detection of murine and human antigen-specific CD8 T cells

scientific article published on 20 June 2019

CD4+ T cell effector commitment coupled to self-renewal by asymmetric cell divisions.

scientific article published on 06 December 2016

CD8+ T Cells Utilize Highly Dynamic Enhancer Repertoires and Regulatory Circuitry in Response to Infections.

scientific article published on 10 December 2016

CD8+ T Lymphocyte Self-Renewal during Effector Cell Determination

scientific article

Cell-autonomous requirement for TCF1 and LEF1 in the development of Natural Killer T cells.

scientific article

Critical requirement of GABPalpha for normal T cell development

scientific article

Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.

scientific article published on 30 September 2016

Cutting Edge: Tcf1 Instructs T Follicular Helper Cell Differentiation by Repressing Blimp1 in Response to Acute Viral Infection

scientific article published on 12 July 2019

Cutting Edge: β-Catenin-Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions.

scientific article published on 27 March 2017

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

scientific article published on 02 August 2016

Differential Requirements for Tcf1 Long Isoforms in CD8+ and CD4+ T Cell Responses to Acute Viral Infection.

scientific article

Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1

scientific article

Ectopic Tcf1 expression instills a stem-like program in exhausted CD8+ T cells to enhance viral and tumor immunity

scientific article published on 27 April 2020

Ezh2 programs T differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf

scientific article published in Nature Communications

Fidelity of a BAC-EGFP transgene in reporting dynamic expression of IL-7Rα in T cells.

scientific article published on May 2011

Flux of the L-serine metabolism in rabbit, human, and dog livers. Substantial contributions of both mitochondrial and peroxisomal serine:pyruvate/alanine:glyoxylate aminotransferase

scientific article published on 01 June 1999

Flux of the L-serine metabolism in rat liver. The predominant contribution of serine dehydratase.

scientific article published in June 1999

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.

scientific article published on August 2014

GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells

scientific journal article

GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells.

scientific article

GABPbeta2 is dispensible for normal lymphocyte development but moderately affects B cell responses.

scientific article published on 15 July 2008

Hematopoietic and Leukemic Stem Cells Have Distinct Dependence on Tcf1 and Lef1 Transcription Factors.

scientific article published on 04 April 2016

IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

scientific article published on 23 December 2013

IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes

scientific article

Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.

scientific article published on 20 May 2014

Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

scientific article published on 18 May 2020

Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity.

scientific article

LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6

scientific article

Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas

scientific article published on 17 November 2021

Lef1-dependent hypothalamic neurogenesis inhibits anxiety.

scientific article published on 24 August 2017

MLL4 keeps Foxp3 in the loop.

scientific article published in August 2017

Peripherally induced brain tissue-resident memory CD8+ T cells mediate protection against CNS infection

scientific article published on 22 June 2020

Phenotypic and Functional Alterations in Circulating Memory CD8 T Cells with Time after Primary Infection.

scientific article published on 20 October 2015

Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells

scientific article published on 14 September 2017

Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections

article

Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1.

scientific article published on 21 August 2017

Regulation of mature T cell responses by the Wnt signaling pathway ⬇️

scientific article published on January 12, 2012

Sox2 modulates Lef-1 expression during airway submucosal gland development.

scientific article published on 31 January 2014

Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid Leukemia

scientific article published in January 2018

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development

scientific article published in Nature Communications

Store depletion by caffeine/ryanodine activates capacitative Ca(2+) entry in nonexcitable A549 cells

scientific article published on 01 August 2000

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells

scientific article

TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis

scientific article published on 29 May 2019

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow.

scientific article

Targeting tetramer-forming GABPβ isoforms impairs self-renewal of hematopoietic and leukemic stem cells.

scientific article published on August 2012

Targeting the GA binding protein beta1L isoform does not perturb lymphocyte development and function

scientific article published on 21 April 2008

Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells

scientific article published on 05 March 2019

Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity

scientific article published on 25 April 2016

The IL-15 receptor {alpha} chain cytoplasmic domain is critical for normal IL-15Ralpha function but is not required for trans-presentation

scientific article published on 16 September 2008

The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.

scientific article published on 25 October 2012

The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses.

scientific article published on 2 October 2015

The differentiation of ROR-γt expressing iNKT17 cells is orchestrated by Runx1.

scientific article published on August 2017

The transcription factor GABP is a critical regulator of B lymphocyte development

scientific article published on 01 April 2007

The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage.

scientific article published on 12 June 2017

The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage

scientific article published on 29 July 2019

The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity

scientific article published on 18 February 2019

The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector differentiation.

scientific article published on 20 April 2015

Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses

scientific article

Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.

scientific article published on 25 July 2018

β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation.

scientific article published on 19 October 2015

β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells

scientific article published on 21 August 2020

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