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List of works by Dik C van Gent

A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.

scientific article published on 15 December 2008

A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation.

scientific article

A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination

scientific article published on 21 October 2013

Attenuated XPC expression is not associated with impaired DNA repair in bladder cancer.

scientific article published on 30 April 2015

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

scientific article

C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties

scientific article published on 14 September 2020

Correction to: Role of the DNA damage response in prostate cancer formation, progression and treatment

scientific article published on 01 March 2020

DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP.

scientific article published on October 2002

Decreased immunoglobulin class switching in nijmegen breakage syndrome due to the DNA repair defect ⬇️

scientific article published on December 1, 2001

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

scientific article

Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair

scientific article

Fen-1 facilitates homologous recombination by removing divergent sequences at DNA break ends

scientific article published on August 2005

Functional Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects

article

Functional Expression of Endothelial Nitric Oxide Synthase Fused to Green Fluorescent Protein in Transgenic Mice ⬇️

scientific article published on October 1, 2003

Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA

scientific article published on 17 June 2020

In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies

scientific article published on January 2016

Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner

scientific article published on 16 January 2020

NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication.

scientific article

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

scientific article

Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.

scientific article

Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity

scientific article published on 02 March 2022

Rejoining of DNA by the RAG1 and RAG2 Proteins ⬇️

scientific article published on April 10, 1998

Role of the DNA damage response in prostate cancer formation, progression and treatment

scientific article published on 13 June 2019

The Ku80 carboxy terminus stimulates joining and artemis-mediated processing of DNA ends

scientific article published on 22 December 2008

The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas

scientific article published on 29 September 2020

The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins.

scientific article published in September 2002

The role of DNA dependent protein kinase in synapsis of DNA ends.

scientific article published on December 2003

The role of DNA dependent protein kinase in synapsis of DNA ends.

scientific article

Tumor slice culture system to assess drug response of primary breast cancer

scientific article published in January 2015

XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination.

scientific article

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