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List of works by Sudhakar Jha

Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux.

scientific article published on 3 June 2005

Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes

scientific article

CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation

scientific article

Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump ⬇️

scientific article published on October 24, 2003

Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathway

scientific article

E3 ligase EDD1/UBR5 is utilized by the HPV E6 oncogene to destabilize tumor suppressor TIP60.

scientific article published on 3 August 2015

Functional characterization of Candida albicans ABC transporter Cdr1p.

scientific article published on December 2003

Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: uncommon but conserved Trp326 of Walker B is important for ATP binding.

scientific article published in May 2005

High-Risk Human Papillomaviral Oncogenes E6 and E7 Target Key Cellular Pathways to Achieve Oncogenesis.

scientific article published on 8 June 2018

Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage

scientific article

Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells.

scientific article

Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication

scientific article

MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles

scientific article published on 01 January 2019

RVB1/RVB2: running rings around molecular biology

scientific article

RVBs are required for assembling a functional TIP60 complex

scientific article

Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex

scientific article

TFregulomeR reveals transcription factors' context-specific features and functions

scientific article published on 01 January 2020

TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.

scientific article

TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter.

scientific article published on 18 October 2017

TIP60-miR-22 axis as a prognostic marker of breast cancer progression

scientific article published on 19 October 2015

The oncogenic E3 ligase TRIP12 suppresses epithelial-mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2

scientific article published on 07 May 2021

Tip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA.

scientific article

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