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List of works by Aloysius J. Klingelhutz

2-(4'-CHLOROPHENYL)-1,4-BENZOQUINONE INCREASES THE FREQUENCY OF MICRONUCLEI AND SHORTENS TELOMERES.

scientific article published on March 2008

A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor.

scientific article published on 11 July 2017

AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes

scientific article

Acrolein-exposed normal human lung fibroblasts in vitro: cellular senescence, enhanced telomere erosion, and degradation of Werner's syndrome protein

scientific article

Adipocytes are susceptible to Ebola Virus infection

scientific article published on 27 May 2022

Allelic 3p Deletions in High-Grade Carcinomas After Transformation In Vitro of Human Uroepithelial Cells ⬇️

scientific article published on September 1, 1991

Amplification of the chromosome 20q region is associated with expression of HPV-16 E7 in human airway and anogenital epithelial cells.

scientific article

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

scientific article published in November 1998

Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk viruses

scientific article published on 27 January 2012

Chronic superantigen exposure induces systemic inflammation, elevated bloodstream endotoxin, and abnormal glucose tolerance in rabbits: possible role in diabetes

scientific article

Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.

scientific article published on 14 November 2008

Co-regulation of p16INK4A and migratory genes in culture conditions that lead to premature senescence in human keratinocytes.

scientific article

Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity

scientific article published on 27 December 2016

DNA damage responses and oxidative stress in dyskeratosis congenita

scientific article

Differential Activation of Human Keratinocytes by Leishmania Species Causing Localized or Disseminated Disease

scientific article

Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity

scientific article published on 10 August 2016

Does Staphylococcus aureus have a role in the development of Type 2 diabetes mellitus?

scientific article published on 6 October 2015

Effects of telomerase and viral oncogene expression on the in vitro growth of human chondrocytes

scientific article published on 01 February 2002

Enhanced radiation sensitivity in HPV-positive head and neck cancer

scientific article published on 07 June 2013

Epstein-Barr virus immediate-early protein BZLF1 inhibits tumor necrosis factor alpha-induced signaling and apoptosis by downregulating tumor necrosis factor receptor 1

scientific article

Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.

scientific article published on November 2003

ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers

scientific article

Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.

scientific article published on 9 May 2003

HPV16-E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300.

scientific article published on October 2006

Human papillomavirus (HPV) type 18 induces extended growth in primary human cervical, tonsillar, or foreskin keratinocytes more effectively than other high-risk mucosal HPVs.

scientific article published on 09 September 2009

Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner

scientific article published on June 2006

Identification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cells

scientific article published on 08 September 2013

Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors.

scientific article published on April 2004

Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway

scientific article

Low-temperature electrospun silk scaffold for in vitro mucosal modeling.

scientific article published on 11 January 2012

Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers.

scientific article published in March 2013

Microarray analysis identifies differentiation-associated genes regulated by human papillomavirus type 16 E6.

scientific article published on September 2003

Nonrandom chromosome losses in tumorigenic revertants of hybrids between isogeneic immortal and neoplastic human uroepithelial cells ⬇️

scientific article published on November 1, 1991

Novel Staphylococcus aureus Secreted Protein Alters Keratinocyte Proliferation and Elicits a Proinflammatory Response In Vitro and In Vivo

scientific article published on 15 July 2015

PCB126 blocks the thermogenic beiging response of adipocytes

scientific article published on 12 November 2019

PCB126 inhibits adipogenesis of human preadipocytes

scientific article

PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats

scientific article published on 22 September 2015

Papillomavirus E6 oncoproteins

scientific article

Pdgfrα-Cre mediated knockout of the aryl hydrocarbon receptor protects mice from high-fat diet induced obesity and hepatic steatosis

scientific article published on 30 July 2020

Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells

scientific article

Proliferative defects in dyskeratosis congenita skin keratinocytes are corrected by expression of the telomerase reverse transcriptase, TERT, or by activation of endogenous telomerase through expression of papillomavirus E6/E7 or the telomerase RNA c

article published in 2010

RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner

scientific article

SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis

scientific article published on 24 April 2017

Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery.

scientific article published on 11 January 2018

Staphylococcal superantigens stimulate immortalized human adipocytes to produce chemokines

scientific article

Staphylococcal β-Toxin Modulates Human Aortic Endothelial Cell and Platelet Function through Sphingomyelinase and Biofilm Ligase Activities

scientific article

Suppression of Resting Metabolism by the Angiotensin AT2 Receptor

scientific article published on 27 July 2016

Telomerase activation and cancer.

scientific article

Telomerase activation in cervical keratinocytes containing stably replicating human papillomavirus type 16 episomes.

scientific article published on September 2002

Telomerase activity as a potential diagnostic marker for triage of abnormal Pap smears.

scientific article

Telomerase reverse transcriptase subunit expression is associated with chondrosarcoma malignancy.

scientific article published on September 2004

Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

scientific article

Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6.

scientific article published in April 2004

Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.

scientific article published on 23 March 2007

The Epstein-Barr virus immediate-early protein BZLF1 induces expression of E2F-1 and other proteins involved in cell cycle progression in primary keratinocytes and gastric carcinoma cells.

scientific article

The Superantigen Toxic Shock Syndrome Toxin-1 Alters Human Aortic Endothelial Cell Function.

scientific article published on 11 December 2017

The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1.

scientific article

The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency.

scientific article published on 17 January 2011

The role of human papillomavirus 16 E6 in anchorage-independent and invasive growth of mouse tonsil epithelium.

scientific article

The role of telomeres in the ageing of human skin.

scientific article published on 03 March 2011

Therapeutic opportunities: telomere maintenance in inducible pluripotent stem cells.

scientific article

p53 null mutations are associated with a telomerase negative phenotype in ovarian carcinoma

scientific article

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