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List of works by Françoise Dantzer

A PARP1-ERK2 synergism is required for the induction of LTP

scientific article

A dual approach in the study of poly (ADP-ribose) polymerase: in vitro random mutagenesis and generation of deficient mice

scientific article published on 01 March 1999

A fast signal-induced activation of Poly(ADP-ribose) polymerase: a novel downstream target of phospholipase c.

scientific article published in July 2000

A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells

scientific article

Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export.

scientific article published on 30 September 2016

Base excision repair is impaired in mammalian cells lacking Poly(ADP-ribose) polymerase-1.

scientific article published on June 2000

Base removers and strand scissors: different strategies employed in base excision and strand incision at modified base residues in DNA.

scientific article

Cell death associated with abnormal mitosis observed by confocal imaging in live cancer cells.

scientific article published on 21 August 2013

Characterisation of a gain-of-function mutant of poly(ADP-ribose) polymerase.

scientific article published on July 1995

Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways

scientific article

Coordinated signals from PARP-1 and PARP-2 are required to establish a proper T cell immune response to breast tumors in mice

scientific article published on 30 January 2020

Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function

scientific article published on 17 April 2019

Decreasing Poly(ADP-Ribose) Polymerase Activity Restores ΔF508 CFTR Trafficking.

scientific article published on 12 September 2012

Distinct mechanisms for opposite functions of homeoproteins Cdx2 and HoxB7 in double-strand break DNA repair in colon cancer cells.

scientific article published on 19 February 2016

Expanding functions of ADP-ribosylation in the maintenance of genome integrity

scientific article published on 23 September 2016

Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication

scientific article published on April 15, 1998

Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.

scientific article

Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes.

scientific article published on 12 August 2009

Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks.

scientific article

Modulation of glycolysis induction in primary cultures of rabbit kidney proximal tubule cells: the role of shaking, glucose and insulin

scientific article published on 01 October 1993

New readers and interpretations of poly(ADP-ribosyl)ation

scientific article published on 03 July 2012

PARG deficiency is neither synthetic lethal with BRCA1 nor PTEN deficiency

scientific article published on July 2016

PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress

scientific article

PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.

scientific article published on 9 April 2018

PARP-1/PARP-2 double deficiency in mouse T cells results in faulty immune responses and T lymphomas.

scientific article published on 09 February 2017

PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors.

scientific article

PARP-3, a DNA-dependent PARP with emerging roles in double-strand break repair and mitotic progression

scientific article published on 01 April 2011

PARP1 and Poly(ADP-ribosyl)ation Signaling during Autophagy in Response to Nutrient Deprivation

scientific article published on 09 June 2019

PARP2 deficiency affects invariant-NKT-cell maturation and protects mice from concanavalin A-induced liver injury.

scientific article published on 27 July 2017

PARP2 mediates branched poly ADP-ribosylation in response to DNA damage

scientific article published in Nature Communications

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

scientific article

PARP3 comes to light as a prime target in cancer therapy

scientific article published on 29 May 2019

PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis.

scientific article published on 26 August 2016

PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers

scientific article published on 15 November 2018

Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in mice

scientific article published on 15 May 2013

Parp3 negatively regulates immunoglobulin class switch recombination.

scientific article published on 22 May 2015

Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation

scientific article published on 06 November 2020

Pharmacological inhibition of poly(ADP-ribose) polymerase (PARP) activity in PARP-1 silenced tumour cells increases chemosensitivity to temozolomide and to a N3-adenine selective methylating agent

scientific article

Phenotypic characterization of Parp-1 and Parp-2 deficient mice and cells.

scientific article published in January 2011

Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions

scientific article

Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

scientific article

Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis

scholarly article

Poly(ADP-ribose) polymerase: structure-function relationship

scientific article published on 01 January 1995

Poly(ADP-ribose) polymerases in double-strand break repair: focus on PARP1, PARP2 and PARP3.

scientific article published on 10 July 2014

Poly(ADP-ribose): novel functions for an old molecule

scientific article (publication date: July 2006)

Purification of Recombinant Human PARG and Activity Assays.

scientific article published in January 2017

Purification of Recombinant Human PARP-3.

scientific article published in January 2017

Purification of recombinant poly(ADP-ribose) polymerases.

scientific article

Radiation-induced mitotic catastrophe in PARG-deficient cells.

scientific article

Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice

scientific article

The diverse roles and clinical relevance of PARPs in DNA damage repair: current state of the art.

scientific article published on 31 March 2012

The expanding field of poly(ADP-ribosyl)ation reactions. 'Protein Modifications: Beyond the Usual Suspects' Review Series.

scientific article published on 17 October 2008

The expanding field of poly(ADP-ribosyl)ation reactions. ‘Protein Modifications: Beyond the Usual Suspects' Review Series.

scientific article published on 7 November 2008

The expanding role of PARPs in the establishment and maintenance of heterochromatin.

scientific article published on 27 June 2013

The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.

scientific article

The role of poly(ADP-ribosyl)ation in epigenetic events.

scientific article published on 14 August 2008

Therapeutic considerations of PARP in stem cell biology: Relevance in cancer and beyond

scientific article published on 13 June 2019

Toward specific functions of poly(ADP-ribose) polymerase-2.

scientific article

[From poly(ADP-ribose) discovery to PARP inhibitors in cancer therapy]

scientific article published on 15 September 2015

[PARP inhibitors: significant progress in cancer therapy]

scientific article published on 01 March 2011