List of works by Adrian P Bracken

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

scientific article published in April 2018

A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence

scientific article

A model for transmission of the H3K27me3 epigenetic mark

scientific article published on 19 October 2008

Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

scientific article

CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression

scientific article

Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription

scientific article

Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer

scientific article published on 23 May 2019

Delineating transcriptional networks of prognostic gene signatures refines treatment recommendations for lymph node-negative breast cancer patients.

scientific article published on 20 June 2015

Detection of novel germline mutations for breast cancer in non-BRCA1/2 families

scientific article published on 20 June 2015

Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements

scientific article published on 5 April 2017

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

scientific article published on 15 September 2016

E2F target genes: unraveling the biology

scientific article published in August 2004

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

scientific article published on February 2001

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

scientific article

Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.

scientific article published on 29 May 2017

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

scientific article (publication date: May 2006)

H3K79 methylation profiles define murine and human MLL-AF4 leukemias

scientific article published on November 2008

MED23: a new Mediator of H2B monoubiquitylation

scientific article published on 5 October 2015

NPAT expression is regulated by E2F and is essential for cell cycle progression

scientific article

Native gel analysis of macromolecular protein complexes in cultured mammalian cells

scientific article published on 29 July 2015

PRC2 functions in development and congenital disorders

scientific article published on 01 October 2019

PRC2 mediated H3K27 methylations in cellular identity and cancer.

scientific article

PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation

scientific article published on 11 September 2019

Phenotypic analysis of familial breast cancer: comparison of BRCAx tumors with BRCA1-, BRCA2-carriers and non-familial breast cancer.

scientific article published on 17 February 2015

Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation

scientific article

Polycomb group proteins in cell cycle progression and cancer.

scientific article published in April 2004

Polycomb group proteins: navigators of lineage pathways led astray in cancer

scientific article

Profiling cancer

scientific article

Protein-truncating variants in moderate-risk breast cancer susceptibility genes: a meta-analysis of high-risk case-control screening studies

scientific article published on 14 June 2015

Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation.

scientific article published on 20 May 2013

Stem Cell Epigenetics: Looking Forward

scientific article published on 01 June 2014

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

scientific article

The 3D Genome: EZH2 Comes into the Fold

scientific article published on 15 March 2019

The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.

scientific article published on 22 March 2018

The PCL1-p53 axis promotes cellular quiescence.

scientific article published on 10 December 2015

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

scientific article

The polycomb group protein Suz12 is required for embryonic stem cell differentiation

scientific article published on 5 March 2007

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis

scientific journal article

Transcriptomics: unravelling the biology of transcription factors and chromatin remodelers during development and differentiation.

scientific article published on 12 August 2009

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