List of works - Mark W Head

A case of protease sensitive prionopathy in a patient in the UK.

scientific article published on 7 August 2009

A case of variably protease-sensitive prionopathy treated with doxycyclin

scientific article published on 9 January 2015

A new index of agonal state for neurological disease

scientific article published on 01 October 2011

A new prionopathy.

scientific article

A novel seven-octapeptide repeat insertion in the prion protein gene (PRNP) in a Dutch pedigree with Gerstmann-Sträussler-Scheinker disease phenotype: comparison with similar cases from the literature

scientific article

A prion protein epitope selective for the pathologically misfolded conformation

scientific article

Abnormal prion protein in the pituitary in sporadic and variant Creutzfeldt-Jakob disease

scientific article

Abnormal prion protein in the retina of the most commonly occurring subtype of sporadic Creutzfeldt-Jakob disease.

scientific article published on September 2005

Advances in the development of a screening test for variant Creutzfeldt–Jakob disease

scientific article published on 01 February 2008

Ageing in the chick lens: in vitro studies.

scientific article published on March 1991

An antibody to the aggregated synthetic prion protein peptide (PrP106-126) selectively recognizes disease-associated prion protein (PrP) from human brain specimens

scientific article

Application of Atomic Dielectric Resonance Spectroscopy for the screening of blood samples from patients with clinical variant and sporadic CJD.

scientific article

Application of an immunocapillary electrophoresis assay to the detection of abnormal prion protein in brain, spleen and blood specimens from patients with variant Creutzfeldt-Jakob disease

scientific article published in October 2006

Application of magnetic field–induced heat shock protein 70 for presurgical cytoprotection

scientific article published on 01 December 1998

Biology and neuropathology of prion diseases

scientific article published in January 2008

Clinicopathological phenotype of codon 129 valine homozygote sporadic Creutzfeldt-Jakob disease

scientific article published on 01 October 2000

Comparison of the level, distribution and form of disease-associated prion protein in variant and sporadic Creutzfeldt-Jakob diseased brain using conformation-dependent immunoassay and Western blot

scientific article published on 01 December 2010

Coordinate and independent regulation of alpha B-crystallin and hsp27 expression in response to physiological stress.

scientific article

Correction: The Distribution of Prion Protein Allotypes Differs Between Sporadic and Iatrogenic Creutzfeldt-Jakob Disease Patients

scientific article published on 8 March 2016

Correlation of Polydispersed Prion Protein and Characteristic Pathology in the Thalamus in Variant Creutzfeldt-Jakob Disease: Implication of Small Oligomeric Species

scientific article published on 03 November 2010

Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease

scientific article

Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease

scientific article

Differential protein profiling as a potential multi-marker approach for TSE diagnosis

scientific article published on 27 November 2009

Disease-associated prion protein is not detectable in human systemic amyloid deposits

scientific article published on 01 December 2007

Distinct stability states of disease-associated human prion protein identified by conformation-dependent immunoassay

scientific article

Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK.

scientific article

Effects of age and genetic growth rate on the crystallin composition of the chick lens.

scientific article published on December 1994

Effects of human PrPSc type and PRNP genotype in an in-vitro conversion assay

scientific article published in December 2008

Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells

scientific article published on 01 September 1997

Evaluation of urinary PrPSc as a diagnostic test for sporadic, variant, and familial CJD.

scientific article published in May 2005

Evidence for the extralenticular expression of members of the β-crystallin gene family in the chick and a comparison with δ-crystallin during differentiation and transdifferentiation

article

Exploring the zoonotic potential of animal prion diseases: in vivo and in vitro approaches.

scientific article published on January 2014

Expression of the chicken cysteine-rich fibroblast growth factor receptor (CFR) during embryogenesis and retina development

scientific article published on 01 March 1996

Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice

scientific article published on February 1998

Further characterisation of the prion protein molecular types detectable in the NIBSC Creutzfeldt-Jakob disease brain reference materials

scientific article

Genotype-dependent molecular evolution of sheep bovine spongiform encephalopathy (BSE) prions in vitro affects their zoonotic potential

scientific article

Gerstmann-Straüssler-Scheinker disease: novel PRNP mutation and VGKC-complex antibodies

scientific article

Human embryonic stem cells rapidly take up and then clear exogenous human and animal prions in vitro.

scientific article

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrP) associated with variant Creutzfeldt-Jakob disease

scientific article published on 29 October 2008

Human prion diseases: Molecular, cellular and population biology ⬇️

scientific article published on January 20, 2013

Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner

scientific article published on 15 November 2017

Human tonsil-derived follicular dendritic-like cells are refractory to human prion infection in vitro and traffic disease-associated prion protein to lysosomes

scientific article

Immunohistochemistry for the prion protein: comparison of different monoclonal antibodies in human prion disease subtypes.

scientific article published in January 2002

In vitro amplification and detection of variant Creutzfeldt-Jakob disease PrPSc.

scientific article

Inter-laboratory assessment of PrPSc typing in creutzfeldt-jakob disease: a Western blot study within the NeuroPrion Consortium

scientific article published on 2 July 2008

Investigation of prion diseases.

scientific article

Laboratory diagnosis of variant Creutzfeldt-Jakob disease.

scientific article

Localization of delta-crystallin RNA during lens morphogenesis and differentiation in the normal and talpid3 chick embryo

scientific article published on September 1, 1992

Macular holes: migratory gaps and vitreous as obstacles to glial closure

scientific article published on 01 August 1997

Molecular barriers to zoonotic transmission of prions

scientific article published on January 2014

Molecular model of prion transmission to humans

scientific article

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc

scholarly article

Myc-mediated transactivation of HSP70 expression following exposure to magnetic fields

scientific article published on 01 May 1998

Neuropathology and molecular biology of variant Creutzfeldt-Jakob disease.

scientific article

Neuropathology of variant Creutzfeldt-Jakob disease.

scientific article

No major change in vCJD agent strain after secondary transmission via blood transfusion

scientific article

Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients.

scientific article

Pathological and biochemical investigation of a woman diagnosed with genetic Creutzfeldt-Jakob disease shortly after parturition

scientific article published on 2 May 2015

Peripheral tissue involvement in sporadic, iatrogenic, and variant Creutzfeldt-Jakob disease: an immunohistochemical, quantitative, and biochemical study

scientific article

Phenotypic variability in human prion diseases.

scientific article

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient

scientific article

Predicting susceptibility and incubation time of human-to-human transmission of vCJD.

scientific article published in May 2006

Prion protein accumulation and neuroprotection in hypoxic brain damage

scientific article

Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease

scientific article

Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002.

scientific article published in June 2004

Production and Characterization of a Panel of Monoclonal Antibodies Against Native Human Cellular Prion Protein

scientific article published on 01 February 2009

Properties of the cellular prion protein expressed in Xenopus oocytes

scientific article published in July 2002

Purification of normal cellular prion protein from human platelets and the formation of a high molecular weight prion protein complex following platelet activation

scientific article published in September 2005

RNA integrity in post mortem human variant Creutzfeldt-Jakob disease (vCJD) and control brain tissue.

scientific article published on October 2011

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease

scientific article

Relative Abundance of apoE and Aβ1-42 Associated with Abnormal Prion Protein Differs between Creutzfeldt-Jakob Disease Subtypes

scientific article

Review: Creutzfeldt-Jakob disease: prion protein type, disease phenotype and agent strain.

scientific article published on June 2012

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion

scientific article

Specificity of lymphoreticular accumulation of prion protein for variant Creutzfeldt-Jakob disease.

scientific article published on March 2004

Sporadic Creutzfeldt-Jakob disease in a young Dutch valine homozygote: atypical molecular phenotype.

scientific article

Sporadic Creutzfeldt-Jakob disease: discrete subtypes or a spectrum of disease?

scientific article published on 16 September 2009

Sporadic Creutzfeldt-Jakob disease: further twists and turns in a convoluted protein

scientific article published in September 2006

Standards for the assay of Creutzfeldt-Jakob disease specimens

scientific article published in June 2004

Suppression of fibroblast growth factor 2 expression by antisense oligonucleotides inhibits embryonic chick neural retina cell differentiation and survival in vivo ⬇️

scientific article published on May 1, 1998

The Distribution of Prion Protein Allotypes Differs Between Sporadic and Iatrogenic Creutzfeldt-Jakob Disease Patients

scientific article published on 3 February 2016

The application of in vitro cell-free conversion systems to human prion diseases

scientific article published on 10 June 2010

The contribution of different prion protein types and host polymorphisms to clinicopathological variations in Creutzfeldt-Jakob disease

scientific article published on 28 February 2012

The prion protein protease sensitivity, stability and seeding activity in variably protease sensitive prionopathy brain tissue suggests molecular overlaps with sporadic Creutzfeldt-Jakob disease

scientific article

The transmissible spongiform encephalopathies: pathogenic mechanisms and strategies for therapeutic intervention

scientific article

Transcription regulation of alpha B-crystallin in astrocytes: analysis of HSF and AP1 activation by different types of physiological stress

scientific article published on 01 May 1996

Transmissions of variant Creutzfeldt-Jakob disease from brain and lymphoreticular tissue show uniform and conserved bovine spongiform encephalopathy-related phenotypic properties on primary and secondary passage in wild-type mice

scientific article published on 5 August 2009

Transplantation of ocular tissue from a donor with sporadic Creutzfeldt-Jakob disease

scientific article published in September 2006

UK Iatrogenic Creutzfeldt-Jakob disease: investigating human prion transmission across genotypic barriers using human tissue-based and molecular approaches

scientific article

Uptake and degradation of protease-sensitive and -resistant forms of abnormal human prion protein aggregates by human astrocytes

scientific article

Variably protease-sensitive prionopathy in a PRNP codon 129 heterozygous UK patient with co-existing tau, α synuclein and Aβ pathology

scientific article published on 03 November 2010

Variably protease-sensitive prionopathy in the UK: a retrospective review 1991-2008.

scientific article published on April 2013

Variant CJD. 18 years of research and surveillance

scientific article

Variant Creutzfeldt-Jakob disease

scientific article published on 01 March 2003

Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain

scientific article

Variation in concentration of prion protein in the peripheral blood of patients with variant and sporadic Creutzfeldt-Jakob disease detected by dissociation enhanced lanthanide fluoroimmunoassay and flow cytometry

scientific article published in April 2005

vCJD and the gut: implications for endoscopy

scientific article published on January 2007

βB2-Crystallin in the mammalian retina

scientific article published on 01 October 1995

List of works by Mark W Head

A case of protease sensitive prionopathy in a patient in the UK.

A case of variably protease-sensitive prionopathy treated with doxycyclin

A new index of agonal state for neurological disease

A new prionopathy.

A novel seven-octapeptide repeat insertion in the prion protein gene (PRNP) in a Dutch pedigree with Gerstmann-Sträussler-Scheinker disease phenotype: comparison with similar cases from the literature

A prion protein epitope selective for the pathologically misfolded conformation

Abnormal prion protein in the pituitary in sporadic and variant Creutzfeldt-Jakob disease

Abnormal prion protein in the retina of the most commonly occurring subtype of sporadic Creutzfeldt-Jakob disease.

Advances in the development of a screening test for variant Creutzfeldt–Jakob disease

Ageing in the chick lens: in vitro studies.

An antibody to the aggregated synthetic prion protein peptide (PrP106-126) selectively recognizes disease-associated prion protein (PrP) from human brain specimens

Application of Atomic Dielectric Resonance Spectroscopy for the screening of blood samples from patients with clinical variant and sporadic CJD.

Application of an immunocapillary electrophoresis assay to the detection of abnormal prion protein in brain, spleen and blood specimens from patients with variant Creutzfeldt-Jakob disease

Application of magnetic field–induced heat shock protein 70 for presurgical cytoprotection

Biology and neuropathology of prion diseases

Clinicopathological phenotype of codon 129 valine homozygote sporadic Creutzfeldt-Jakob disease

Comparison of the level, distribution and form of disease-associated prion protein in variant and sporadic Creutzfeldt-Jakob diseased brain using conformation-dependent immunoassay and Western blot

Coordinate and independent regulation of alpha B-crystallin and hsp27 expression in response to physiological stress.

Correction: The Distribution of Prion Protein Allotypes Differs Between Sporadic and Iatrogenic Creutzfeldt-Jakob Disease Patients

Correlation of Polydispersed Prion Protein and Characteristic Pathology in the Thalamus in Variant Creutzfeldt-Jakob Disease: Implication of Small Oligomeric Species

Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease

Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease

Differential protein profiling as a potential multi-marker approach for TSE diagnosis

Disease-associated prion protein is not detectable in human systemic amyloid deposits

Distinct stability states of disease-associated human prion protein identified by conformation-dependent immunoassay

Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK.

Effects of age and genetic growth rate on the crystallin composition of the chick lens.

Effects of human PrPSc type and PRNP genotype in an in-vitro conversion assay

Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells

Evaluation of urinary PrPSc as a diagnostic test for sporadic, variant, and familial CJD.

Evidence for the extralenticular expression of members of the β-crystallin gene family in the chick and a comparison with δ-crystallin during differentiation and transdifferentiation

Exploring the zoonotic potential of animal prion diseases: in vivo and in vitro approaches.

Expression of the chicken cysteine-rich fibroblast growth factor receptor (CFR) during embryogenesis and retina development

Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice

Further characterisation of the prion protein molecular types detectable in the NIBSC Creutzfeldt-Jakob disease brain reference materials

Genotype-dependent molecular evolution of sheep bovine spongiform encephalopathy (BSE) prions in vitro affects their zoonotic potential

Gerstmann-Straüssler-Scheinker disease: novel PRNP mutation and VGKC-complex antibodies

Human embryonic stem cells rapidly take up and then clear exogenous human and animal prions in vitro.

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrP) associated with variant Creutzfeldt-Jakob disease

Human prion diseases: Molecular, cellular and population biology ⬇️

Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner

Human tonsil-derived follicular dendritic-like cells are refractory to human prion infection in vitro and traffic disease-associated prion protein to lysosomes

Immunohistochemistry for the prion protein: comparison of different monoclonal antibodies in human prion disease subtypes.

In vitro amplification and detection of variant Creutzfeldt-Jakob disease PrPSc.

Inter-laboratory assessment of PrPSc typing in creutzfeldt-jakob disease: a Western blot study within the NeuroPrion Consortium

Investigation of prion diseases.

Laboratory diagnosis of variant Creutzfeldt-Jakob disease.

Localization of delta-crystallin RNA during lens morphogenesis and differentiation in the normal and talpid3 chick embryo

Macular holes: migratory gaps and vitreous as obstacles to glial closure

Molecular barriers to zoonotic transmission of prions

Molecular model of prion transmission to humans

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc

Myc-mediated transactivation of HSP70 expression following exposure to magnetic fields

Neuropathology and molecular biology of variant Creutzfeldt-Jakob disease.

Neuropathology of variant Creutzfeldt-Jakob disease.

No major change in vCJD agent strain after secondary transmission via blood transfusion

Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients.

Pathological and biochemical investigation of a woman diagnosed with genetic Creutzfeldt-Jakob disease shortly after parturition

Peripheral tissue involvement in sporadic, iatrogenic, and variant Creutzfeldt-Jakob disease: an immunohistochemical, quantitative, and biochemical study

Phenotypic variability in human prion diseases.

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient

Predicting susceptibility and incubation time of human-to-human transmission of vCJD.

Prion protein accumulation and neuroprotection in hypoxic brain damage

Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease

Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002.

Production and Characterization of a Panel of Monoclonal Antibodies Against Native Human Cellular Prion Protein

Properties of the cellular prion protein expressed in Xenopus oocytes

Purification of normal cellular prion protein from human platelets and the formation of a high molecular weight prion protein complex following platelet activation

RNA integrity in post mortem human variant Creutzfeldt-Jakob disease (vCJD) and control brain tissue.

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease

Relative Abundance of apoE and Aβ1-42 Associated with Abnormal Prion Protein Differs between Creutzfeldt-Jakob Disease Subtypes

Review: Creutzfeldt-Jakob disease: prion protein type, disease phenotype and agent strain.

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion

Specificity of lymphoreticular accumulation of prion protein for variant Creutzfeldt-Jakob disease.

Sporadic Creutzfeldt-Jakob disease in a young Dutch valine homozygote: atypical molecular phenotype.

Sporadic Creutzfeldt-Jakob disease: discrete subtypes or a spectrum of disease?

Sporadic Creutzfeldt-Jakob disease: further twists and turns in a convoluted protein

Standards for the assay of Creutzfeldt-Jakob disease specimens

Suppression of fibroblast growth factor 2 expression by antisense oligonucleotides inhibits embryonic chick neural retina cell differentiation and survival in vivo ⬇️