List of works - Ylva Ivarsson

A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin

scientific article (publication date: 2013)

A structural portrait of the PDZ domain family

scientific article

Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution

scientific article

An On-pathway Intermediate in the Folding of a PDZ Domain

scientific article published in Journal of Biological Chemistry

Cooperative phosphoinositide and peptide binding by PSD-95/discs large/ZO-1 (PDZ) domain of polychaetoid, Drosophila zonulin

scientific article published on 27 October 2011

Discovery of short linear motif-mediated interactions through phage display of intrinsically disordered regions of the human proteome

scientific article

Engineered Symmetric Connectivity of Secondary Structure Elements Highlights Malleability of Protein Folding Pathways

scientific article published in 2009

Engineering the enantioselectivity of glutathione transferase by combined active-site mutations and chemical modifications

scientific article

Extensions of PSD-95/discs large/ZO-1 (PDZ) domains influence lipid binding and membrane targeting of syntenin-1

scientific article

Folding and misfolding in a naturally occurring circularly permuted PDZ domain

scientific article published on 7 February 2008

Folding and stability of globular proteins and implications for function

scientific article published on 21 January 2009

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

scientific journal article

High-throughput discovery of functional disordered regions.

scientific article published on 22 May 2018

High-throughput methods for identification of protein-protein interactions involving short linear motifs.

scientific article published on 22 August 2015

Identification and characterization of protein folding intermediates

scientific article published on 24 April 2007

Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign

scientific article (publication date: 7 March 2003)

Improved affinity at the cost of decreased specificity: a recurring theme in PDZ-peptide interactions

scientific article

Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs

scientific article published on 05 January 2021

Interaction analysis through proteomic phage display.

scientific article

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

scientific article published on 19 November 2021

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

scientific journal article

Let There Be Light!

scientific article

Mechanism of Na(+) binding to thrombin resolved by ultra-rapid kinetics.

scientific article published on 29 September 2007

Mechanisms of protein folding

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

scientific article published on 29 May 2011

Plasticity of PDZ domains in ligand recognition and signaling.

scientific article published on 21 April 2012

Pooled screening for antiproliferative inhibitors of protein-protein interactions.

scientific article

Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments

scientific article

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome

scientific article published on 01 January 2022

Proteome-wide analysis of phospho-regulated PDZ domain interactions

article

Proteomic peptide phage display uncovers novel interactions of the PDZ1-2 supramodule of syntenin

scientific journal article

Regio- and enantioselectivities in epoxide conjugations are modulated by residue 210 in Mu class glutathione transferases

scientific article

Selectivity of aggregation-determining interactions

scientific article

Structural basis of Sorcin-mediated calcium-dependent signal transduction

scientific article published on 18 November 2015

Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain

article published in 2010

Structural diversity of PDZ-lipid interactions

scientific article published on March 2010

Syndecan-syntenin-ALIX regulates the biogenesis of exosomes

scientific article

Syntenin, a syndecan adaptor and an Arf6 phosphatidylinositol 4,5-bisphosphate effector, is essential for epiboly and gastrulation cell movements in zebrafish

scientific article published on 7 March 2012

The folding pathway of an engineered circularly permuted PDZ domain

scientific article published on 5 January 2008

List of works by Ylva Ivarsson

A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin

A structural portrait of the PDZ domain family

Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution

An On-pathway Intermediate in the Folding of a PDZ Domain

Cooperative phosphoinositide and peptide binding by PSD-95/discs large/ZO-1 (PDZ) domain of polychaetoid, Drosophila zonulin

Discovery of short linear motif-mediated interactions through phage display of intrinsically disordered regions of the human proteome

Engineered Symmetric Connectivity of Secondary Structure Elements Highlights Malleability of Protein Folding Pathways

Engineering the enantioselectivity of glutathione transferase by combined active-site mutations and chemical modifications

Extensions of PSD-95/discs large/ZO-1 (PDZ) domains influence lipid binding and membrane targeting of syntenin-1

Folding and misfolding in a naturally occurring circularly permuted PDZ domain

Folding and stability of globular proteins and implications for function

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

High-throughput discovery of functional disordered regions.

High-throughput methods for identification of protein-protein interactions involving short linear motifs.

Identification and characterization of protein folding intermediates

Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign

Improved affinity at the cost of decreased specificity: a recurring theme in PDZ-peptide interactions

Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs

Interaction analysis through proteomic phage display.

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

Let There Be Light!

Mechanism of Na(+) binding to thrombin resolved by ultra-rapid kinetics.

Mechanisms of protein folding

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

Plasticity of PDZ domains in ligand recognition and signaling.

Pooled screening for antiproliferative inhibitors of protein-protein interactions.

Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome

Proteome-wide analysis of phospho-regulated PDZ domain interactions

Proteomic peptide phage display uncovers novel interactions of the PDZ1-2 supramodule of syntenin

Regio- and enantioselectivities in epoxide conjugations are modulated by residue 210 in Mu class glutathione transferases

Selectivity of aggregation-determining interactions

Structural basis of Sorcin-mediated calcium-dependent signal transduction

Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain

Structural diversity of PDZ-lipid interactions

Syndecan-syntenin-ALIX regulates the biogenesis of exosomes

Syntenin, a syndecan adaptor and an Arf6 phosphatidylinositol 4,5-bisphosphate effector, is essential for epiboly and gastrulation cell movements in zebrafish

The folding pathway of an engineered circularly permuted PDZ domain