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List of works by Janine T. Erler

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.

scientific article

Author Correction: Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

scientific article published on 16 March 2020

Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

scientific article

Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours

scientific article

Bold alliances aid translational work

scientific article published in Nature

Brain cancer spreads

scientific article published in July 2014

Cancer cells' ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

scientific article published on 09 August 2018

Comparison of (18)F-FET and (18)F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma

scientific article

Contrasting effects of sunitinib within in vivo models of metastasis

scientific article

Correlation of Ultrasound Shear Wave Elastography with Pathological Analysis in a Xenografic Tumour Model

scientific article

Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism

scientific article published on 23 October 2015

Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

scientific article published on 08 November 2019

Disabling defences in the brain

scientific article published in Nature

Division Induced Dynamics in Non-Invasive and Invasive Breast Cancer

article

Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments

scientific article published in September 2017

Dynamics of cancerous tissue correlates with invasiveness.

scientific article published on 06 March 2017

Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.

scientific article published on 2 November 2017

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

scientific article

Framing cancer progression: influence of the organ- and tumour-specific matrisome

scientific article published on 23 January 2020

Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

scientific article

Hypoxia promotes invasion and metastasis of breast cancer cells by increasing lysyl oxidase expression

article by Janine T. Erler et al published June 2005 in Breast Cancer Research

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

scientific article published on April 2004

Hypoxia-mediated metastasis

scientific article published on January 2014

Hypoxic Signalling in Tumour Stroma.

scientific article published on 29 May 2018

ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

scientific article published on 12 June 2017

Identification of hypoxia-regulated proteins using MALDI-mass spectrometry imaging combined with quantitative proteomics

scientific article

Interplay Between LOX Enzymes and Integrins in the Tumor Microenvironment

scientific article published on 26 May 2019

Ionizing radiation induces tumor cell lysyl oxidase secretion

scientific article

Kinome-wide decoding of network-attacking mutations rewiring cancer signaling

scientific article

LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling

scientific article published on January 2013

Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis

scientific article

Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.

scientific article

Lysyl oxidase in cancer research

scientific article

Lysyl oxidase in colorectal cancer

scientific article published on 05 September 2013

Lysyl oxidase mediates hypoxic control of metastasis

scientific article

Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis

scientific article published on 19 July 2007

Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction.

scientific article published on 10 August 2015

Matrix crosslinking forces tumor progression by enhancing integrin signaling

scientific article

Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments

scientific article published on 03 June 2019

Molecular Pathways: Connecting Fibrosis and Solid Tumor Metastasis

scientific article published on 01 July 2014

Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight

scientific article

Navigating cancer network attractors for tumor-specific therapy

Network Medicine Strikes a Blow against Breast Cancer

scientific article published on 01 May 2012

Network-based drugs and biomarkers

scientific article published on January 2010

Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate

scientific article published on 02 July 2018

Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients

scientific article published on 26 May 2016

Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer

scientific article

Pre-metastatic niches: organ-specific homes for metastases.

scientific article published on 17 March 2017

Proteomic Characterization of Caenorhabditis elegans Larval Development

scientific article published on 27 November 2017

Pten Regulates Epithelial Cytodifferentiation during Prostate Development

scientific article published on 15 June 2015

Quantification of Lung Metastases from In Vivo Mouse Models

scientific article published on January 2016

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

scientific article

Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1.

scientific article published on 27 October 2005

STRIPAK components determine mode of cancer cell migration and metastasis.

scientific article published on 22 December 2014

Stimulating translational research: several European life science institutions put their heads together.

scientific article published on 5 August 2015

Structural ECM components in the premetastatic and metastatic niche

scientific article

Targeting ECM Disrupts Cancer Progression

scientific article

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

scientific article published on 15 June 2015

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.

scientific article published on 27 May 2015

The potential for LOXL2 as a target for future cancer treatment.

scientific article published in June 2011

The potential for targeting extracellular LOX proteins in human malignancy

scientific article

The pre-metastatic niche: is metastasis random?

scientific article

The rationale for targeting the LOX family in cancer

scientific article published on 19 July 2012

The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis

scientific article

Three-dimensional context regulation of metastasis

scientific article published on 24 September 2008

Tissue section AFM: In situ ultrastructural imaging of native biomolecules

scientific article

Tumor endothelial marker 8 promotes cancer progression and metastasis

scientific article published on 10 July 2018

Tumor-secreted LOXL2 activates fibroblasts through FAK signaling

scientific article published on 05 September 2013