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List of works by Adam C. Palmer

A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity

scientific article published on 19 November 2019

A mathematical model for transcriptional interference by RNA polymerase traffic in Escherichia coli

scientific article published on 23 December 2004

A proof of concept for biomarker-guided targeted therapy against ovarian cancer based on patient-derived tumor xenografts

scientific article published on 03 August 2020

Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming

scientific article published on 08 May 2019

Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas

scientific article published on 29 November 2018

Chemical decay of an antibiotic inverts selection for resistance

scientific article published on 01 March 2010

Chemical decay of an antibiotic inverts selection for resistance.

scientific article

Chemical probes: The many genes of drug mechanism

scientific article published on January 2016

Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or Synergy

scientific article published in December 2017

Comparing the Efficacy of Cancer Therapies between Subgroups in Basket Trials

scientific article published on 01 November 2020

Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes

scientific article

Directing traffic on DNA-How transcription factors relieve or induce transcriptional interference.

scientific article published on 27 January 2017

Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones

scientific article published on 14 August 2020

Guidance for data collection and computational modelling of regulatory networks

scientific article

Modeling the impact of drug interactions on therapeutic selectivity

scientific article published in Nature Communications

Nonoptimal Gene Expression Creates Latent Potential for Antibiotic Resistance

scientific article published on 01 November 2018

Opposing effects of target overexpression reveal drug mechanisms

scientific article published on July 2014

Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors

scientific article published on March 2016

Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments

scientific article published on 20 January 2016

Potent transcriptional interference by pausing of RNA polymerases over a downstream promoter

scientific article published on June 2009

Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

scientific article published on 19 January 2022

RNA polymerase pausing at a protein roadblock can enhance transcriptional interference by promoter occlusion

scientific article published on 29 March 2019

Regulatory Dynamics Determine Cell Fate following Abrupt Antibiotic Exposure

scientific article published on 31 October 2017

The role of repressor kinetics in relief of transcriptional interference between convergent promoters

scientific article published on 4 July 2016

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

scientific article published on 04 December 2019

Transcriptional interference by RNA polymerase pausing and dislodgement of transcription factors.

scientific article

Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance.

scientific article published on 19 February 2013

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