List of works - Charlene S Dezzutti

A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study).

scientific article published on 5 May 2015

A Phase 1 Trial to Assess the Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics of a Novel Dapivirine Vaginal Film.

scientific article

A rapid microassay for measuring the luminol-dependent chemiluminescent response in canine whole blood

scientific article published on 01 September 1991

Absence of human T-lymphotropic virus type I tax sequences in a population of normal blood donors in the Baltimore, MD/Washington, DC, area: results from a multicenter study.

scientific article published in August 1999

Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?

scientific article

Antiviral activity of genital tract secretions after oral or topical tenofovir pre-exposure prophylaxis for HIV-1.

scientific article published on May 2014

Assessing the potential of the Woman's Condom for vaginal drug delivery

scientific article

Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study

scientific article published on 17 May 2008

Broadly Neutralizing Anti-HIV Antibodies Prevent HIV Infection of Mucosal Tissue Ex Vivo

scientific article published on 23 November 2015

Can a topical microbicide prevent rectal HIV transmission?

scientific article

Cervical and prostate primary epithelial cells are not productively infected but sequester human immunodeficiency virus type 1.

scientific article published on 13 March 2001

Cervical shedding of human T cell lymphotropic virus type I is associated with cervicitis

scientific article

Characterization of UC781-tenofovir combination gel products for HIV-1 infection prevention in an ex vivo ectocervical model.

scientific article

Characterization of a B-cell immunodominant epitope of human T-lymphotropic virus type 1 (HTLV-I) envelope gp46.

scientific article published in September 1992

Characterization of human T-lymphotropic virus type I- and II-infected T-cell lines: antigenic, phenotypic, and genotypic analysis.

scientific article published on July 1993

Correction: Performance of Swabs, Lavage, and Diluents to Quantify Biomarkers of Female Genital Tract Soluble Mucosal Mediators.

scientific article published on 26 January 2012

Cryopreservation of Human Mucosal Leukocytes

scientific article

Cryopreservation of human mucosal tissues

scientific article published in PLoS ONE

Detection of human T-lymphotropic virus (HTLV) tax sequences in New York City blood donors seronegative for HTLV types 1 and 2

scientific article published in July 2003

Development of HIV-1 rectal-specific microbicides and colonic tissue evaluation

scientific article (publication date: 2014)

Distinct Pharmacodynamic Activity of Rilpivirine in Ectocervical and Colonic Explant Tissue

scientific article published on 22 February 2016

Effect of topical microbicides on infectious human immunodeficiency virus type 1 binding to epithelial cells

scientific article published on 2 April 2007

Extracts from Acacia catechu suppress HIV-1 replication by inhibiting the activities of the viral protease and Tat.

scientific article published on 18 October 2013

FeLV-induced immunosuppression through alterations in signal transduction: down regulation of protein kinase C

scientific article published on 01 May 1989

Formulation and characterization of polymeric films containing combinations of antiretrovirals (ARVs) for HIV prevention

scientific article

HIV-1 infection of female genital tract tissue for use in prevention studies

scientific article published on August 2013

HIV-1 specific IgA detected in vaginal secretions of HIV uninfected women participating in a microbicide trial in Southern Africa are primarily directed toward gp120 and gp140 specificities

scientific article

HIV-Specific Cytotoxic T Lymphocytes, HLA-A11, and Chemokine-Related Factors May Act Synergistically to Determine HIV Resistance in CCR5 Δ32-Negative Female Sex Workers in Chiang Rai, Northern Thailand

article

Impact of Sex on the Pharmacokinetics and Pharmacodynamics of 1% Tenofovir Gel

scientific article

In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide

scientific article

In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories

scientific article

Involvement of matrix metalloproteinases in human immunodeficiency virus type 1-induced replication by clinical Mycobacterium avium isolates.

scientific article published on October 1999

Is wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activity

scientific article published in 2012

Levels of Genital Tract Defensins and Cytokines Differ between HIV-Uninfected US and African Women

scientific article

Modulation of HTLV-II-associated spontaneous lymphocyte proliferation by beta 2 integrin CD11a/CD18 involves interaction with its cognate ligand, CD54.

scientific article published in June 1994

Mucosal Escherichia coli bactericidal activity and immune mediators are associated with HIV-1 seroconversion in women participating in the HPTN 035 trial

scientific article

Mucosal and systemic antibody responses in humans infected with simian foamy virus

scientific article

Mucosal innate immune factors in the female genital tract are associated with vaginal HIV-1 shedding independent of plasma viral load.

scientific article published in August 2006

Multisite comparison of anti-human immunodeficiency virus microbicide activity in explant assays using a novel endpoint analysis

scientific article published on 02 September 2009

Performance of swabs, lavage, and diluents to quantify biomarkers of female genital tract soluble mucosal mediators

scientific article

Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention

scientific article

Preclinical testing of candidate topical microbicides for anti-human immunodeficiency virus type 1 activity and tissue toxicity in a human cervical explant culture.

scientific article published on 12 March 2007

Prevalence of cryoglobulinemia in hepatitis C virus (HCV) positive patients with and without human immunodeficiency virus (HIV) coinfection.

scientific article published on November 2004

Preventing the sexual transmission of HIV-1 with topical microbicides: another piece of the equation.

scientific article published on 26 September 2007

Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women.

scientific article published on 28 June 2018

Rectal microbicide development.

scientific article

Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations

scientific article

Reformulated tenofovir gel for use as a dual compartment microbicide.

scientific article

Safety and efficacy of tenofovir/IQP-0528 combination gels - a dual compartment microbicide for HIV-1 prevention

scientific article

Sensitivity and specificity of a DNA polymerase chain reaction nonisotopic-based detection method for the confirmation of infection with human T-lymphotropic virus types I and II.

scientific article published in August 1996

Soluble Immune Mediators and Vaginal Bacteria Impact Innate Genital Mucosal Antimicrobial Activity in Young Women

scientific article

Stromal-derived factor-1 chemokine gene variant is associated with the delay of HIV-1 disease progression in two longitudinal cohorts.

scientific article published in May 2000

Sublimable C5A delivery provides sustained and prolonged anti-HIV microbicidal activities.

scientific article

Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles.

scientific article

The effect of menopause on the innate antiviral activity of cervicovaginal lavage.

scientific article published on 25 March 2015

The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention.

scientific article published on 17 June 2015

Toward early safety alert endpoints: exploring biomarkers suggestive of microbicide failure.

scientific article

Trichomonas vaginalis-induced epithelial monolayer disruption and human immunodeficiency virus type 1 (HIV-1) replication: implications for the sexual transmission of HIV-1

scientific article

Vaginal Microbicide Film Combinations of Two Reverse Transcriptase Inhibitors, EFdA and CSIC, for the Prevention of HIV-1 Sexual Transmission

scientific article published on 21 March 2015

Vaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1.

scientific article

Y chromosome and HIV DNA detection in vaginal swabs as biomarkers of semen and HIV exposure in women

scientific article

List of works by Charlene S Dezzutti

A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study).

A Phase 1 Trial to Assess the Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics of a Novel Dapivirine Vaginal Film.

A rapid microassay for measuring the luminol-dependent chemiluminescent response in canine whole blood

Absence of human T-lymphotropic virus type I tax sequences in a population of normal blood donors in the Baltimore, MD/Washington, DC, area: results from a multicenter study.

Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?

Antiviral activity of genital tract secretions after oral or topical tenofovir pre-exposure prophylaxis for HIV-1.

Assessing the potential of the Woman's Condom for vaginal drug delivery

Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study

Broadly Neutralizing Anti-HIV Antibodies Prevent HIV Infection of Mucosal Tissue Ex Vivo

Can a topical microbicide prevent rectal HIV transmission?

Cervical and prostate primary epithelial cells are not productively infected but sequester human immunodeficiency virus type 1.

Cervical shedding of human T cell lymphotropic virus type I is associated with cervicitis

Characterization of UC781-tenofovir combination gel products for HIV-1 infection prevention in an ex vivo ectocervical model.

Characterization of a B-cell immunodominant epitope of human T-lymphotropic virus type 1 (HTLV-I) envelope gp46.

Characterization of human T-lymphotropic virus type I- and II-infected T-cell lines: antigenic, phenotypic, and genotypic analysis.

Correction: Performance of Swabs, Lavage, and Diluents to Quantify Biomarkers of Female Genital Tract Soluble Mucosal Mediators.

Cryopreservation of Human Mucosal Leukocytes

Cryopreservation of human mucosal tissues

Detection of human T-lymphotropic virus (HTLV) tax sequences in New York City blood donors seronegative for HTLV types 1 and 2

Development of HIV-1 rectal-specific microbicides and colonic tissue evaluation

Distinct Pharmacodynamic Activity of Rilpivirine in Ectocervical and Colonic Explant Tissue

Effect of topical microbicides on infectious human immunodeficiency virus type 1 binding to epithelial cells

Extracts from Acacia catechu suppress HIV-1 replication by inhibiting the activities of the viral protease and Tat.

FeLV-induced immunosuppression through alterations in signal transduction: down regulation of protein kinase C

Formulation and characterization of polymeric films containing combinations of antiretrovirals (ARVs) for HIV prevention

HIV-1 infection of female genital tract tissue for use in prevention studies

HIV-1 specific IgA detected in vaginal secretions of HIV uninfected women participating in a microbicide trial in Southern Africa are primarily directed toward gp120 and gp140 specificities

HIV-Specific Cytotoxic T Lymphocytes, HLA-A11, and Chemokine-Related Factors May Act Synergistically to Determine HIV Resistance in CCR5 Δ32-Negative Female Sex Workers in Chiang Rai, Northern Thailand

Impact of Sex on the Pharmacokinetics and Pharmacodynamics of 1% Tenofovir Gel

In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide

In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories

Involvement of matrix metalloproteinases in human immunodeficiency virus type 1-induced replication by clinical Mycobacterium avium isolates.

Is wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activity

Levels of Genital Tract Defensins and Cytokines Differ between HIV-Uninfected US and African Women

Modulation of HTLV-II-associated spontaneous lymphocyte proliferation by beta 2 integrin CD11a/CD18 involves interaction with its cognate ligand, CD54.

Mucosal Escherichia coli bactericidal activity and immune mediators are associated with HIV-1 seroconversion in women participating in the HPTN 035 trial

Mucosal and systemic antibody responses in humans infected with simian foamy virus

Mucosal innate immune factors in the female genital tract are associated with vaginal HIV-1 shedding independent of plasma viral load.

Multisite comparison of anti-human immunodeficiency virus microbicide activity in explant assays using a novel endpoint analysis

Performance of swabs, lavage, and diluents to quantify biomarkers of female genital tract soluble mucosal mediators

Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention

Preclinical testing of candidate topical microbicides for anti-human immunodeficiency virus type 1 activity and tissue toxicity in a human cervical explant culture.

Prevalence of cryoglobulinemia in hepatitis C virus (HCV) positive patients with and without human immunodeficiency virus (HIV) coinfection.

Preventing the sexual transmission of HIV-1 with topical microbicides: another piece of the equation.

Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women.

Rectal microbicide development.

Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations

Reformulated tenofovir gel for use as a dual compartment microbicide.

Safety and efficacy of tenofovir/IQP-0528 combination gels - a dual compartment microbicide for HIV-1 prevention

Sensitivity and specificity of a DNA polymerase chain reaction nonisotopic-based detection method for the confirmation of infection with human T-lymphotropic virus types I and II.

Soluble Immune Mediators and Vaginal Bacteria Impact Innate Genital Mucosal Antimicrobial Activity in Young Women

Stromal-derived factor-1 chemokine gene variant is associated with the delay of HIV-1 disease progression in two longitudinal cohorts.

Sublimable C5A delivery provides sustained and prolonged anti-HIV microbicidal activities.

Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles.

The effect of menopause on the innate antiviral activity of cervicovaginal lavage.

The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention.

Toward early safety alert endpoints: exploring biomarkers suggestive of microbicide failure.

Trichomonas vaginalis-induced epithelial monolayer disruption and human immunodeficiency virus type 1 (HIV-1) replication: implications for the sexual transmission of HIV-1

Vaginal Microbicide Film Combinations of Two Reverse Transcriptase Inhibitors, EFdA and CSIC, for the Prevention of HIV-1 Sexual Transmission

Vaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1.

Y chromosome and HIV DNA detection in vaginal swabs as biomarkers of semen and HIV exposure in women