List of works - David B Jacoby

Abnormalities in neural control of smooth muscle in virus-infected airways

scientific article published on October 1990

Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum.

scientific article published in May 2006

Anticholinergic therapy for airway diseases.

scientific article published in April 2001

Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity

scientific article

Antigen-induced hyperreactivity to histamine: role of the vagus nerves and eosinophils.

scientific article published in May 1999

Atropine pretreatment enhances airway hyperreactivity in antigen-challenged guinea pigs through an eosinophil-dependent mechanism

scientific article

Autologous skeletal myoblasts transplanted to ischemia-damaged myocardium in humans. Histological analysis of cell survival and differentiation

scientific article published on 01 March 2003

Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons

scientific article

Characterization of GTP-binding proteins coupled to inhibition of adenylyl cyclase in guinea pig tracheal epithelial cells

scientific article published on 01 June 1994

Characterization of side population cells from human airway epithelium

scientific article

Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression

scientific article

Comparison of fresh and cryopreserved porcine ventral mesencephalon cells transplanted in A rat model of Parkinson's disease.

scientific article

Cultures of airway parasympathetic nerves express functional M2 muscarinic receptors.

scientific article published in December 1996

Dexamethasone prevents virus-induced hyperresponsiveness via multiple mechanisms.

scientific article published on 25 April 2003

Diverse cholinergic receptors in the cat carotid chemosensory unit

scientific article published on 01 January 2003

Double-stranded RNA causes airway hyperreactivity and neuronal M2 muscarinic receptor dysfunction.

scientific article published in April 2002

Dual p38/JNK mitogen activated protein kinase inhibitors prevent ozone-induced airway hyperreactivity in guinea pigs

scientific article

Effect of inflammatory cell mediators on M2 muscarinic receptors in the lungs

scientific article

Effects of dexamethasone on antigen-induced airway eosinophilia and M(2) receptor dysfunction

scientific article published on 01 May 2001

Effects of inflammatory cells on neuronal M2 muscarinic receptor function in the lung.

scientific article

Effects of neurokinin receptor antagonists in virus-infected airways.

scientific article published in July 2000

Effects of tachykinin NK1 receptor antagonists on vagal hyperreactivity and neuronal M2 muscarinic receptor function in antigen challenged guinea-pigs

scientific article

Eosinophil adhesion to cholinergic nerves via ICAM-1 and VCAM-1 and associated eosinophil degranulation.

scientific article

Eosinophil recruitment to the airway nerves.

scientific article

Eosinophil-associated inflammation in bronchial asthma: a connection to the nervous system.

scientific article published on May 1995

Eosinophils increase airway sensory nerve density in mice and in human asthma

scientific article published on 01 September 2018

Eosinophils increase neuron branching in human and murine skin and in vitro.

scientific article

Expression and regulation of intercellular adhesion molecule-1 on airway parasympathetic nerves.

scientific article published on 5 April 2007

Function of pulmonary M2 muscarinic receptors in antigen-challenged guinea pigs is restored by heparin and poly-L-glutamate

scientific article published on December 1992

Glucocorticoid treatment increases inhibitory m(2) muscarinic receptor expression and function in the airways.

scientific article published in April 2001

Human and Mouse Eosinophils Have Antiviral Activity against Parainfluenza Virus.

scientific article

Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor

scientific article

Human mucosal associated invariant T cells detect bacterially infected cells

scientific article

Hyperinsulinemia potentiates airway responsiveness to parasympathetic nerve stimulation in obese rats

scientific article

IL-1 receptors mediate persistent, but not acute, airway hyperreactivity to ozone in guinea pigs.

scientific article published on 10 July 2008

Increased function of inhibitory neuronal M2 muscarinic receptors in diabetic rat lungs ⬇️

scientific article published on August 1, 1997

Increased function of inhibitory neuronal M2 muscarinic receptors in trachea and ileum of diabetic rats.

scientific article

Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure

scientific article published on July 1995

Infection of cultured human airway epithelial cells by influenza A virus

scientific article published on January 1991

Influenza infection causes airway hyperresponsiveness by decreasing enkephalinase.

scientific article published on June 1988

Influenza virus A infection induces interleukin-8 gene expression in human airway epithelial cells.

scientific article published in September 1992

Influenza virus induces expression of antioxidant genes in human epithelial cells.

scientific article published in June 1994

Insulin regulates neuronal M2 muscarinic receptor function in the ileum of diabetic rats.

scientific article published on 10 November 2003

Interaction of viral infections with muscarinic receptors.

scientific article

Interactions of eosinophils with nerves.

scientific article published in January 2014

Interleukin-1β mediates virus-induced m2 muscarinic receptor dysfunction and airway hyperreactivity.

scientific article

Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage

scientific article published on May 2007

Ion transport across cat and ferret tracheal epithelia

scientific article published on 01 September 1986

Localization of eosinophils to airway nerves and effect on neuronal M2 muscarinic receptor function

scientific article published on 01 July 1997

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs

scientific article

Methacholine causes reflex bronchoconstriction

scientific article published on 01 January 1999

Muscarinic Receptor Agonists and Antagonists: Effects on Inflammation and Immunity ⬇️

scientific article published on January 1, 2012

NIH conference. Airway inflammation

scientific article

Neural control of airway inflammation.

scientific article

Neuronal eotaxin and the effects of CCR3 antagonist on airway hyperreactivity and M2 receptor dysfunction

scientific article

Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma.

scientific article

Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells

scientific article published on 01 November 2019

Parainfluenza virus infection damages inhibitory M2 muscarinic receptors on pulmonary parasympathetic nerves in the guinea-pig

scientific article published in January 1991

Parainfluenza virus infection of cultured airway epithelial cells

scientific article published in November 1989

Parainfluenza virus type 1 reduces the affinity of agonists for muscarinic receptors in guinea-pig lung and heart

scientific article published in May 1990

Pathophysiology of airway viral infections.

scientific article

Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells

scientific article

Pretreatment with an antibody to interleukin-5 prevents loss of pulmonary M2 muscarinic receptor function in antigen-challenged guinea pigs

scientific article published on 01 March 1995

Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs.

scientific article published in November 1997

Proinflammatory responses of human airway cells to ricin involve stress-activated protein kinases and NF-kappaB.

scientific article published on 14 September 2007

Pulmonary neuronal M2 muscarinic receptor function in asthma and animal models of hyperreactivity

scientific article published on July 1998

Quantifying Nerve Architecture in Murine and Human Airways Using Three-Dimensional Computational Mapping ⬇️

scientific article published on October 25, 2012

Retinoic acid prevents virus-induced airway hyperreactivity and M2 receptor dysfunction via anti-inflammatory and antiviral effects

scientific article published on 22 May 2009

Role of TNF-α in virus-induced airway hyperresponsiveness and neuronal M₂ muscarinic receptor dysfunction

scientific article

Role of apoptotic signaling pathways in regulation of inflammatory responses to ricin in primary murine macrophages

scientific article published on 25 January 2007

Role of macrophages in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction.

scientific article

Role of oxidants in influenza virus-induced gene expression.

scientific article

Role of the respiratory epithelium in asthma.

scientific article published on January 1997

Selective O-desulfation produces nonanticoagulant heparin that retains pharmacological activity in the lung.

scientific article published in July 1997

Selective muscarinic receptor antagonists for airway diseases

scientific article

Structure of the human M(2) muscarinic acetylcholine receptor gene and its promoter

scientific article

Substance P-induced airway hyperreactivity is mediated by neuronal M(2) receptor dysfunction.

scientific article published in September 2000

Synergism between rhinovirus infection and oxidant pollutant exposure enhances airway epithelial cell cytokine production

scientific article

The changing role of eosinophils in long-term hyperreactivity following a single ozone exposure.

scientific article published on 27 May 2005

The effects of epithelial cell supernatant on contractions of isolated canine tracheal smooth muscle.

scientific article published on October 1988

The influence of sensitization on mechanisms of organophosphorus pesticide-induced airway hyperreactivity

scientific article

The therapeutic potential of Toll-like receptor 7 stimulation in asthma

scientific article

Tissue optical clearing, three-dimensional imaging, and computer morphometry in whole mouse lungs and human airways.

scientific article

Toll-like receptor 7 agonists are potent and rapid bronchodilators in guinea pigs.

scientific article

Toll-like receptor 7 rapidly relaxes human airways.

scientific article published on September 2013

Toll-like receptor-2/6 and Toll-like receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs.

scientific article published on June 2013

Upping the antedrug: is a novel anti-inflammatory Toll-like receptor 7 agonist also a bronchodilator?

scientific article

Viral infection increases contractile but not secretory responses to substance P in ferret trachea ⬇️

scientific article published on February 1, 1992

Viral infection induces dependence of neuronal M2 muscarinic receptors on cyclooxygenase in guinea pig lung.

scientific article published on July 1996

Virus induces airway hyperresponsiveness to tachykinins: role of neutral endopeptidase.

scientific article published in October 1989

Virus- and interferon-induced loss of inhibitory M2 muscarinic receptor function and gene expression in cultured airway parasympathetic neurons.

scientific article published on July 1998

Virus-Induced Airway Hyperresponsiveness — Possible Involvement of Neural Mechanisms

scientific article published on December 1, 1991

Virus-induced asthma attacks

scientific article published on 01 February 2002

Virus-induced asthma attacks.

scientific article published in January 2004

β2-Agonists inhibit TNF-α-induced ICAM-1 expression in human airway parasympathetic neurons

scientific article

List of works by David B Jacoby

Abnormalities in neural control of smooth muscle in virus-infected airways

Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum.

Anticholinergic therapy for airway diseases.

Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity

Antigen-induced hyperreactivity to histamine: role of the vagus nerves and eosinophils.

Atropine pretreatment enhances airway hyperreactivity in antigen-challenged guinea pigs through an eosinophil-dependent mechanism

Autologous skeletal myoblasts transplanted to ischemia-damaged myocardium in humans. Histological analysis of cell survival and differentiation

Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons

Characterization of GTP-binding proteins coupled to inhibition of adenylyl cyclase in guinea pig tracheal epithelial cells

Characterization of side population cells from human airway epithelium

Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression

Comparison of fresh and cryopreserved porcine ventral mesencephalon cells transplanted in A rat model of Parkinson's disease.

Cultures of airway parasympathetic nerves express functional M2 muscarinic receptors.

Dexamethasone prevents virus-induced hyperresponsiveness via multiple mechanisms.

Diverse cholinergic receptors in the cat carotid chemosensory unit

Double-stranded RNA causes airway hyperreactivity and neuronal M2 muscarinic receptor dysfunction.

Dual p38/JNK mitogen activated protein kinase inhibitors prevent ozone-induced airway hyperreactivity in guinea pigs

Effect of inflammatory cell mediators on M2 muscarinic receptors in the lungs

Effects of dexamethasone on antigen-induced airway eosinophilia and M(2) receptor dysfunction

Effects of inflammatory cells on neuronal M2 muscarinic receptor function in the lung.

Effects of neurokinin receptor antagonists in virus-infected airways.

Effects of tachykinin NK1 receptor antagonists on vagal hyperreactivity and neuronal M2 muscarinic receptor function in antigen challenged guinea-pigs

Eosinophil adhesion to cholinergic nerves via ICAM-1 and VCAM-1 and associated eosinophil degranulation.

Eosinophil recruitment to the airway nerves.

Eosinophil-associated inflammation in bronchial asthma: a connection to the nervous system.

Eosinophils increase airway sensory nerve density in mice and in human asthma

Eosinophils increase neuron branching in human and murine skin and in vitro.

Expression and regulation of intercellular adhesion molecule-1 on airway parasympathetic nerves.

Function of pulmonary M2 muscarinic receptors in antigen-challenged guinea pigs is restored by heparin and poly-L-glutamate

Glucocorticoid treatment increases inhibitory m(2) muscarinic receptor expression and function in the airways.

Human and Mouse Eosinophils Have Antiviral Activity against Parainfluenza Virus.

Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor

Human mucosal associated invariant T cells detect bacterially infected cells

Hyperinsulinemia potentiates airway responsiveness to parasympathetic nerve stimulation in obese rats

IL-1 receptors mediate persistent, but not acute, airway hyperreactivity to ozone in guinea pigs.

Increased function of inhibitory neuronal M2 muscarinic receptors in diabetic rat lungs ⬇️

Increased function of inhibitory neuronal M2 muscarinic receptors in trachea and ileum of diabetic rats.

Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure

Infection of cultured human airway epithelial cells by influenza A virus

Influenza infection causes airway hyperresponsiveness by decreasing enkephalinase.

Influenza virus A infection induces interleukin-8 gene expression in human airway epithelial cells.

Influenza virus induces expression of antioxidant genes in human epithelial cells.

Insulin regulates neuronal M2 muscarinic receptor function in the ileum of diabetic rats.

Interaction of viral infections with muscarinic receptors.

Interactions of eosinophils with nerves.

Interleukin-1β mediates virus-induced m2 muscarinic receptor dysfunction and airway hyperreactivity.

Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage

Ion transport across cat and ferret tracheal epithelia

Localization of eosinophils to airway nerves and effect on neuronal M2 muscarinic receptor function

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs

Methacholine causes reflex bronchoconstriction

Muscarinic Receptor Agonists and Antagonists: Effects on Inflammation and Immunity ⬇️

NIH conference. Airway inflammation

Neural control of airway inflammation.

Neuronal eotaxin and the effects of CCR3 antagonist on airway hyperreactivity and M2 receptor dysfunction

Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma.

Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells

Parainfluenza virus infection damages inhibitory M2 muscarinic receptors on pulmonary parasympathetic nerves in the guinea-pig

Parainfluenza virus infection of cultured airway epithelial cells

Parainfluenza virus type 1 reduces the affinity of agonists for muscarinic receptors in guinea-pig lung and heart

Pathophysiology of airway viral infections.

Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells

Pretreatment with an antibody to interleukin-5 prevents loss of pulmonary M2 muscarinic receptor function in antigen-challenged guinea pigs

Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs.

Proinflammatory responses of human airway cells to ricin involve stress-activated protein kinases and NF-kappaB.

Pulmonary neuronal M2 muscarinic receptor function in asthma and animal models of hyperreactivity

Quantifying Nerve Architecture in Murine and Human Airways Using Three-Dimensional Computational Mapping ⬇️

Retinoic acid prevents virus-induced airway hyperreactivity and M2 receptor dysfunction via anti-inflammatory and antiviral effects

Role of TNF-α in virus-induced airway hyperresponsiveness and neuronal M₂ muscarinic receptor dysfunction

Role of apoptotic signaling pathways in regulation of inflammatory responses to ricin in primary murine macrophages

Role of macrophages in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction.

Role of oxidants in influenza virus-induced gene expression.

Role of the respiratory epithelium in asthma.

Selective O-desulfation produces nonanticoagulant heparin that retains pharmacological activity in the lung.

Selective muscarinic receptor antagonists for airway diseases

Structure of the human M(2) muscarinic acetylcholine receptor gene and its promoter

Substance P-induced airway hyperreactivity is mediated by neuronal M(2) receptor dysfunction.

Synergism between rhinovirus infection and oxidant pollutant exposure enhances airway epithelial cell cytokine production

The changing role of eosinophils in long-term hyperreactivity following a single ozone exposure.