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List of works by Jesse S Boehm

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

scientific article published on 3 October 2017

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

scientific article published on 08 April 2019

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

scientific article published in November 2017

A combination CDK4/6 and IGF1R inhibitor strategy for Ewing sarcoma

scientific article published on 05 November 2018

A first-generation pediatric cancer dependency map

scientific article published on 22 March 2021

A public genome-scale lentiviral expression library of human ORFs

scientific article

AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer

scientific article

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

scientific article published on 20 December 2019

Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers

scientific article

An ecosystem of cancer cell line factories to support a cancer dependency map.

scientific article published on 16 June 2015

Building the Connectivity Map of epigenetics: chromatin profiling by quantitative targeted mass spectrometry.

scientific article published on 6 November 2014

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

scientific article

CK1epsilon is required for breast cancers dependent on beta-catenin activity

scientific article

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

scientific article (publication date: 16 December 2010)

Cancer genetics: Finding the right mix

scientific article published on 01 October 2005

Characterizing genomic alterations in cancer by complementary functional associations

scientific article published on 18 April 2016

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

scientific article

Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase

scientific article

Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.

scientific article published on August 2017

Defining a Cancer Dependency Map.

scientific article

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

scientific article

Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling

scientific article published on 20 January 2020

Emerging Opportunities for Target Discovery in Rare Cancers

scientific article published in September 2017

Erratum: Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

scientific article published in September 2017

From cell lines to living biosensors: new opportunities to prioritize cancer dependencies using ex vivo tumor cultures

scientific article published on 01 February 2019

Functional Genomic Characterization of Cancer Genomes

scientific article published on 4 November 2016

Functional analysis of single cells identifies a rare subset of circulating tumor cells with malignant traits

scientific article

Functional genomics and cancer drug target discovery.

scientific article published on June 2010

GeNets: a unified web platform for network-based genomic analyses.

scientific article

Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival

scientific article published on 07 June 2021

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

scientific article published on September 2016

Genetic interrogation of circulating multiple myeloma cells at single-cell resolution

scientific article

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

scientific article published on 9 August 2017

Global computational alignment of tumor and cell line transcriptional profiles

scientific article published on 04 January 2021

High-throughput Phenotyping of Lung Cancer Somatic Mutations

scientific article published on 28 July 2016

High-throughput Phenotyping of Lung Cancer Somatic Mutations

scientific article published in December 2017

Highly parallel identification of essential genes in cancer cells

scholarly article

Immortalized cells as experimental models to study cancer.

scientific article

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

scientific article published in Nature Communications

In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene

scientific article published on 02 January 2014

Integrated genetic and pharmacologic interrogation of rare cancers

scientific article

Integrative genomic approaches identify IKBKE as a breast cancer oncogene

scientific article

Integrative genomic approaches to understanding cancer.

scientific article published on 11 February 2009

MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

scientific article published on 11 February 2016

MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma

scientific article

Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects

scientific article published on 21 July 2015

NetSig: network-based discovery from cancer genomes.

scientific article published on 4 December 2017

Next-generation characterization of the Cancer Cell Line Encyclopedia

scientific article published on 08 May 2019

Organoid Modeling of the Tumor Immune Microenvironment

scientific article published on 01 December 2018

PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

scientific article

PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling.

scientific article

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

scientific article published on 30 September 2014

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

scientific article published on 11 November 2014

Patient-derived xenografts undergo mouse-specific tumor evolution.

scientific article published on 9 October 2017

Recurrent and functional regulatory mutations in breast cancer

scientific article published on 28 June 2017

Renal medullary carcinomas depend upon loss and are sensitive to proteasome inhibition

scientific article published on 12 March 2019

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

scientific article published on 6 November 2017

Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma

scientific article

Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

scientific article published on 01 December 2020

Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells

scientific article

Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles

scientific article

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

scientific article (publication date: 5 November 2009)

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

scientific article

Systematic morphological profiling of human gene and allele function via Cell Painting.

scientific article published on 18 March 2017

TMOD-14. A PATIENT-DERIVED CANCER CELL LINE ATLAS OF PRIMARY AND METASTATIC CENTRAL NERVOUS SYSTEM TUMORS

Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4

scientific article published on August 2012

The Cancer Dependency Map enables drug mechanism-of-action investigations

scientific article published on 01 July 2020

The landscape of somatic copy-number alteration across human cancers

scientific article

Towards patient-based cancer therapeutics

scientific article

Towards systematic functional characterization of cancer genomes

scientific article published on 17 June 2011

Transformation of human and murine fibroblasts without viral oncoproteins

scientific article

Understanding transformation: progress and gaps

scientific article

WRN helicase is a synthetic lethal target in microsatellite unstable cancers

scientific article published on 10 April 2019

Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development

scientific article

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

scientific article

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