List of works - Tim Formosa

A kinase's work is never done: Rad53 monitors chromatin near replication origins.

scientific article published on 15 February 2011

A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.

scientific article

Avoiding a fatal attraction: properties of nucleosomes and a histone chaperone revealed under physiological conditions

scientific article published on 01 March 2010

Crystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 Domain

scientific article

Establishment and Maintenance of Chromatin Architecture Are Promoted Independently of Transcription by the Histone Chaperone FACT and H3-K56 Acetylation in Saccharomyces cerevisiae

scientific article published on 24 January 2019

FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs

scientific article

FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics

scientific article published on 25 January 2019

Identifying DNA replication complex components using protein affinity chromatography

scientific article published on 01 January 1995

Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone.

scientific article published on 30 May 2011

Large-scale ATP-independent nucleosome unfolding by a histone chaperone.

scientific article

Multiple Nhp6 molecules are required to recruit Spt16-Pob3 to form yFACT complexes and to reorganize nucleosomes.

scientific article

Opposing roles for Set2 and yFACT in regulating TBP binding at promoters

scientific article

Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.

scientific article

Structure and Biological Importance of the Spn1-Spt6 Interaction, and Its Regulatory Role in Nucleosome Binding

scientific article

Structure of the Blm10-20 S proteasome complex by cryo-electron microscopy. Insights into the mechanism of activation of mature yeast proteasomes.

scientific article

Structure of the Spt16 Middle Domain Reveals Functional Features of the Histone Chaperone FACT

scientific article

Suppressors of the temperature sensitivity of DNA polymerase α mutations in Saccharomyces cerevisiae ⬇️

scientific article published on February 1, 1998

The Abundant Histone Chaperones Spt6 and FACT Collaborate to Assemble, Inspect, and Maintain Chromatin Structure in Saccharomyces cerevisiae.

scientific article

The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition

scientific article

The yeast FACT complex has a role in transcriptional initiation.

scientific article

Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication

scientific article published on July 2010

Using protein affinity chromatography to probe structure of protein machines.

scientific article published in January 1991

blm3-1 is an allele of UBP3, a ubiquitin protease that appears to act during transcription of damaged DNA

scientific article published on 30 August 2006

yFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacement

scientific article

List of works by Tim Formosa

A kinase's work is never done: Rad53 monitors chromatin near replication origins.

A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.

Avoiding a fatal attraction: properties of nucleosomes and a histone chaperone revealed under physiological conditions

Crystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 Domain

Establishment and Maintenance of Chromatin Architecture Are Promoted Independently of Transcription by the Histone Chaperone FACT and H3-K56 Acetylation in Saccharomyces cerevisiae

FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs

FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics

Identifying DNA replication complex components using protein affinity chromatography

Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone.

Large-scale ATP-independent nucleosome unfolding by a histone chaperone.

Multiple Nhp6 molecules are required to recruit Spt16-Pob3 to form yFACT complexes and to reorganize nucleosomes.

Opposing roles for Set2 and yFACT in regulating TBP binding at promoters

Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.

Structure and Biological Importance of the Spn1-Spt6 Interaction, and Its Regulatory Role in Nucleosome Binding

Structure of the Blm10-20 S proteasome complex by cryo-electron microscopy. Insights into the mechanism of activation of mature yeast proteasomes.

Structure of the Spt16 Middle Domain Reveals Functional Features of the Histone Chaperone FACT

Suppressors of the temperature sensitivity of DNA polymerase α mutations in Saccharomyces cerevisiae ⬇️

The Abundant Histone Chaperones Spt6 and FACT Collaborate to Assemble, Inspect, and Maintain Chromatin Structure in Saccharomyces cerevisiae.

The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition

The yeast FACT complex has a role in transcriptional initiation.

Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication

Using protein affinity chromatography to probe structure of protein machines.

blm3-1 is an allele of UBP3, a ubiquitin protease that appears to act during transcription of damaged DNA

yFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacement