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List of works by Franck Verrecchia

5-fluorouracil blocks transforming growth factor-beta-induced alpha 2 type I collagen gene (COL1A2) expression in human fibroblasts via c-Jun NH2-terminal kinase/activator protein-1 activation

scientific article published in September 2003

A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis

scientific article published on 13 March 2013

A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression.

scientific article published on 7 November 2002

ATP counteracts the rundown of gap junctional channels of rat ventricular myocytes by promoting protein phosphorylation

scientific article published on 01 April 1999

Advanced glycation end products regulate extracellular matrix protein and protease expression by human glomerular mesangial cells.

scientific article published in April 2009

Analysis of gap junctional intercellular communications using a dielectrophoresis-based microchip

scientific article published on 6 February 2017

Antagonistic Functions of Connexin 43 during the Development of Primary or Secondary Bone Tumors

scientific article published on 26 August 2020

Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases

scientific article

Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression

scientific article

Bone Morphogenetic Protein 2 and Transforming Growth Factor β1 Inhibit the Expression of the Proinflammatory Cytokine IL-34 in Rheumatoid Arthritis Synovial Fibroblasts

scientific article published on 17 November 2016

Cellules souches mésenchymateuses et immunomodulation : vers de nouvelles stratégies immunosuppressives pour le traitement des maladies auto-immunes ?

scientific article published in March 2009

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation

scientific article

Connexin43 intercellular communication drives the early differentiation of human bone marrow stromal cells into osteoblasts

scientific article published on 30 March 2017

Contraceptive gossypol blocks cell-to-cell communication in human and rat cells

scientific article published on 01 October 1996

Control of connective tissue gene expression by TGF beta: role of Smad proteins in fibrosis.

scientific article

Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism.

scientific article

Dephosphorylation agents depress gap junctional communication between rat cardiac cells without modifying the Connexin43 phosphorylation degree

scientific article published on 01 December 2000

Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing.

scientific article published on May 2003

Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha.

scientific article published on 22 October 2002

Do specific antifibrotic properties of immunosuppressive drugs used in the treatment of systemic sclerosis exist?

scientific article

Downregulation of human type VII collagen (COL7A1) promoter activity by dexamethasone. Identification of a glucocorticoid receptor binding region.

scientific article published in February 2001

Evidence of an antifibrotic effect of immunosuppressive drugs: applications in the treatment of systemic sclerosis

scientific article published on January 2009

Evolution of serum cytokine profile after hematopoietic stem cell transplantation in systemic sclerosis patients

scientific article published on 04 April 2016

Expression of transforming growth factor β receptor II in mesenchymal stem cells from systemic sclerosis patients

scientific article published on 7 January 2013

Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling.

scientific article published on 26 October 2007

Fibronectin is distinctly downregulated in murine mammary adenocarcinoma cells with high metastatic potential

scientific article published on 01 December 2006

Fluorescence recovery after photobleaching

scientific article published on 01 January 2001

GLI2-mediated melanoma invasion and metastasis

scientific article

Hippo/YAP Signaling Pathway: A Promising Therapeutic Target in Bone Paediatric Cancers?

scientific article published on 10 March 2020

Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.

scientific article published on 08 March 2001

IgG from patients with pulmonary arterial hypertension and/or systemic sclerosis binds to vascular smooth muscle cells and induces cell contraction

scientific article published on 14 November 2011

Implication of molecular vascular smooth muscle cell heterogeneity among arterial beds in arterial calcification.

scientific article

In vitro evidence for a direct antifibrotic role of the immunosuppressive drug mycophenolate mofetil

scientific article published on 01 February 2007

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

scientific article (publication date: 15 July 2007)

Induction of the AP-1 members c-Jun and JunB by TGF-beta/Smad suppresses early Smad-driven gene activation

scientific article published on 01 April 2001

Influence of the molecular structure of steroids on their ability to interrupt gap junctional communication

scientific article published on 01 February 1996

Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients

scientific article

Involvement of ERK signaling in halofuginone-driven inhibition of fibroblast ability to contract collagen lattices.

scientific article published on 24 July 2007

Loss of connexin43 expression in Ewing's sarcoma cells favors the development of the primary tumor and the associated bone osteolysis.

scientific article published on 9 January 2013

Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes

scientific article published on 20 February 2009

Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?

scientific article published on 16 August 2006

Modulation of gene expression induced in human epidermis by environmental stress in vivo

scientific article published in December 2003

Molecular alterations associated with osteosarcoma development

scientific article

NOVH increases MMP3 expression and cell migration in glioblastoma cells via a PDGFR‐α‐dependent mechanism ⬇️

scientific article published on August 15, 2003

Overexpression of smad7 blocks primary tumor growth and lung metastasis development in osteosarcoma

scientific article

Peripheral blood regulatory T cells in patients with diffuse systemic sclerosis (SSc) before and after autologous hematopoietic SCT: a pilot study

scientific article

Phenotypical and functional characteristics of in vitro expanded bone marrow mesenchymal stem cells from patients with systemic sclerosis

scientific article published on 25 May 2007

Relationship between cytokine profiles and clinical outcomes in patients with systemic sclerosis

scientific article published on 14 August 2010

Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner.

scientific article published in November 2003

Reversible blockade of gap junctional communication by 2,3-butanedione monoxime in rat cardiac myocytes

scientific article published on 01 March 1997

Reversible inhibition of gap junctional communication by tamoxifen in cultured cardiac myocytes

scientific article published on 01 May 1997

Reversible inhibition of gap junctional communication elicited by several classes of lipophilic compounds in cultured rat cardiomyocytes.

scientific article published on November 1997

Reversible interruption of gap junctional communication by testosterone propionate in cultured Sertoli cells and cardiac myocytes

scientific article published on 01 February 1996

Skin involvement in scleroderma--where histological and clinical scores meet

scientific article published on 25 January 2007

Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing's Sarcoma Tumor Growth

scientific article published on 19 November 2020

TGF-beta and TNF-alpha: antagonistic cytokines controlling type I collagen gene expression

scientific article published on August 2004

TGF-beta induces connexin43 gene expression in normal murine mammary gland epithelial cells via activation of p38 and PI3K/AKT signaling pathways

scientific article

TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression

scientific article

TNF-alpha represses connexin43 expression in HaCat keratinocytes via activation of JNK signaling.

scientific article

The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases

article

The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth

scientific article published on 20 December 2020

The steroid receptor co-activator-1 (SRC-1) potentiates TGF-beta/Smad signaling: role of p300/CBP.

scientific article published on March 2005

Therapeutic approach of primary bone tumours by bisphosphonates.

scientific article published on January 2010

Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment.

scientific article published on 30 April 2018

Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation

scientific article

Transforming growth factor-beta signaling through the Smad proteins: role in systemic sclerosis

scientific article published on 5 July 2006

Transforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis.

scientific article published on 31 July 2015

Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation

scientific article (publication date: 29 September 2000)

Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling

scientific article (publication date: 25 July 2002)

[ Gap junctional intercellular communication]

scientific article published on 01 December 2012

[Cellular and molecular mechanisms of fibrosis]

scientific article published on 01 November 2006

[Cytokines in systemic sclerosis]

scientific article published on 08 February 2010

[Functional interactions between the TGF-beta signaling pathway via the Smads and TNF-alpha: implications for the regulation of type I collagen expression]

scientific article published on 01 January 2005

[Gap junctions and bone remodeling]

scientific article published on 04 July 2012

[Involvement of TGFbeta1 in fibrotic diseases: role of its effectors, the Smad proteins]

scientific article published on 22 November 2005

[Sixty years of Pathologie Biologie]

scientific article published on 20 March 2014

c-Fos accelerates hepatocyte conversion to a fibroblastoid phenotype through ERK-mediated upregulation of paxillin-Serine178 phosphorylation.

scientific article

ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis

scientific article published on 17 March 2016

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