List of works - Carmela Giglione

A New Function of p120-GTPase-activating Protein

scientific article published in Journal of Biological Chemistry

Alternative and effective proteomic analysis in Arabidopsis.

scientific article published in October 2007

An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway

scientific article

Chemical Modification of Bacillus thuringiensis Subsp. aizawai δ-Endotoxin : Implication of Arginine Residues in Bombyx mori Toxicity

article

Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features

scientific article

Comparative metagenomics of microbial traits within oceanic viral communities

scientific article

Control of protein life-span by N-terminal methionine excision

scientific article

Cotranslational processing mechanisms: towards a dynamic 3D model

scientific article published on 31 July 2009

Cotranslational proteolysis dominates glutathione homeostasis to support proper growth and development.

scientific article published on 23 October 2009

Differential actions of p60c-Src and Lck kinases on the Ras regulators p120-GAP and GDP/GTP exchange factor CDC25Mm

scientific article (publication date: June 2001)

Discovery and refinement of a new structural class of potent peptide deformylase inhibitors.

scientific article published in January 2007

Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis

scientific article

Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation

scientific article published on 01 July 2020

Dynamics of post-translational modifications and protein stability in the stroma of Chlamydomonas reinhardtii chloroplasts

scientific article published on 4 April 2011

Extent of N-terminal modifications in cytosolic proteins from eukaryotes.

scientific article published in July 2008

Functional and developmental impact of cytosolic protein N-terminal methionine excision in Arabidopsis

scientific article

Golgi traffic and integrity depend on N-myristoyl transferase-1 in Arabidopsis

scientific article

High‐throughput profiling of N‐myristoylation substrate specificity across species including pathogens ⬇️

scientific article published on January 1, 2013

Impact of the N-terminal amino acid on targeted protein degradation

scientific article

Influence of various endogenous and artefact modifications on large-scale proteomics analysis

scientific article published in February 2013

Interplay between N-terminal methionine excision and FtsH protease is essential for normal chloroplast development and function in Arabidopsis.

scientific article published on 18 October 2011

Ion mobility coupled to native mass spectrometry as a relevant tool to investigate extremely small ligand-induced conformational changes.

scientific article published on 24 September 2015

Molecular identification and functional characterization of the first Nα-acetyltransferase in plastids by global acetylome profiling

scientific article

Mutations in three distinct loci cause resistance to peptide deformylase inhibitors in Bacillus subtilis

scientific article published on 26 January 2009

N-myristoylation regulates the SnRK1 pathway in Arabidopsis

scientific article

N-terminal modifications contribute to flowering time and immune response regulations

scientific article published on 11 September 2015

N-terminal protein modifications: Bringing back into play the ribosome

scientific article

NatB-Mediated N-Terminal Acetylation Affects Growth and Biotic Stress Responses

scientific article published on 19 November 2019

New antibiotic molecules: bypassing the membrane barrier of gram negative bacteria increases the activity of peptide deformylase inhibitors

scientific article

New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity

scientific article published on 29 February 2012

Organellar peptide deformylases: universality of the N-terminal methionine cleavage mechanism.

scientific article

Paternal control of embryonic patterning in Arabidopsis thaliana

scientific article published on March 2009

Peptide deformylase as an emerging target for antiparasitic agents

scientific article published on 01 February 2001

Processed N-termini of mature proteins in higher eukaryotes and their major contribution to dynamic proteomics

scientific article published on 8 April 2005

Raf-1 Is Involved in the Regulation of the Interaction between Guanine Nucleotide Exchange Factor and Ha-Ras

scientific article published in Journal of Biological Chemistry

Resistance to anti-peptide deformylase drugs

scientific article published on 01 June 2001

Rice peptide deformylase PDF1B is crucial for development of chloroplasts

scientific article published on 20 August 2008

Roles of N-terminal fatty acid acylations in membrane compartment partitioning: Arabidopsis h-type thioredoxins as a case study

scientific article published on 29 March 2013

Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern

article

Structure-activity relationship analysis of the peptide deformylase inhibitor 5-bromo-1H-indole-3-acetohydroxamic acid

scientific article

Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents

scientific article published on 02 April 2011

Targeted profiling of A. thaliana sub-proteomes illuminates new co- and post-translationally N-terminal Myristoylated proteins

scientific article published on 16 February 2018

The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms

scientific article

The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents

scientific article

The host antimicrobial peptide Bac71-35 binds to bacterial ribosomal proteins and inhibits protein synthesis

scientific article published on 13 November 2014

The intriguing realm of protein biogenesis: Facing the green co-translational protein maturation networks

scientific article

The proteomics of N-terminal methionine cleavage.

scientific article

The situation on antimicrobial agents and chemotherapy in 2002: highlights of the 42nd ICAAC.

scientific article published in December 2002

Tools for analyzing and predicting N-terminal protein modifications

scientific article published on February 2008

Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis

scientific article

Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis.

scientific article published on 12 May 2015

Type 3 peptide deformylases are required for oxidative phosphorylation in Trypanosoma brucei

scientific article published on 26 July 2007

Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart

scientific article

Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote

scientific article published on 11 August 2003

List of works by Carmela Giglione

A New Function of p120-GTPase-activating Protein

Alternative and effective proteomic analysis in Arabidopsis.

An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway

Chemical Modification of Bacillus thuringiensis Subsp. aizawai δ-Endotoxin : Implication of Arginine Residues in Bombyx mori Toxicity

Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features

Comparative metagenomics of microbial traits within oceanic viral communities

Control of protein life-span by N-terminal methionine excision

Cotranslational processing mechanisms: towards a dynamic 3D model

Cotranslational proteolysis dominates glutathione homeostasis to support proper growth and development.

Differential actions of p60c-Src and Lck kinases on the Ras regulators p120-GAP and GDP/GTP exchange factor CDC25Mm

Discovery and refinement of a new structural class of potent peptide deformylase inhibitors.

Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis

Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation

Dynamics of post-translational modifications and protein stability in the stroma of Chlamydomonas reinhardtii chloroplasts

Extent of N-terminal modifications in cytosolic proteins from eukaryotes.

Functional and developmental impact of cytosolic protein N-terminal methionine excision in Arabidopsis

Golgi traffic and integrity depend on N-myristoyl transferase-1 in Arabidopsis

High‐throughput profiling of N‐myristoylation substrate specificity across species including pathogens ⬇️

Impact of the N-terminal amino acid on targeted protein degradation

Influence of various endogenous and artefact modifications on large-scale proteomics analysis

Interplay between N-terminal methionine excision and FtsH protease is essential for normal chloroplast development and function in Arabidopsis.

Ion mobility coupled to native mass spectrometry as a relevant tool to investigate extremely small ligand-induced conformational changes.

Molecular identification and functional characterization of the first Nα-acetyltransferase in plastids by global acetylome profiling

Mutations in three distinct loci cause resistance to peptide deformylase inhibitors in Bacillus subtilis

N-myristoylation regulates the SnRK1 pathway in Arabidopsis

N-terminal modifications contribute to flowering time and immune response regulations

N-terminal protein modifications: Bringing back into play the ribosome

NatB-Mediated N-Terminal Acetylation Affects Growth and Biotic Stress Responses

New antibiotic molecules: bypassing the membrane barrier of gram negative bacteria increases the activity of peptide deformylase inhibitors

New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity

Organellar peptide deformylases: universality of the N-terminal methionine cleavage mechanism.

Paternal control of embryonic patterning in Arabidopsis thaliana

Peptide deformylase as an emerging target for antiparasitic agents

Processed N-termini of mature proteins in higher eukaryotes and their major contribution to dynamic proteomics

Raf-1 Is Involved in the Regulation of the Interaction between Guanine Nucleotide Exchange Factor and Ha-Ras

Resistance to anti-peptide deformylase drugs

Rice peptide deformylase PDF1B is crucial for development of chloroplasts

Roles of N-terminal fatty acid acylations in membrane compartment partitioning: Arabidopsis h-type thioredoxins as a case study

Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern

Structure-activity relationship analysis of the peptide deformylase inhibitor 5-bromo-1H-indole-3-acetohydroxamic acid

Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents

Targeted profiling of A. thaliana sub-proteomes illuminates new co- and post-translationally N-terminal Myristoylated proteins

The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms

The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents

The host antimicrobial peptide Bac71-35 binds to bacterial ribosomal proteins and inhibits protein synthesis

The intriguing realm of protein biogenesis: Facing the green co-translational protein maturation networks

The proteomics of N-terminal methionine cleavage.

The situation on antimicrobial agents and chemotherapy in 2002: highlights of the 42nd ICAAC.

Tools for analyzing and predicting N-terminal protein modifications

Trapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysis

Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis.

Type 3 peptide deformylases are required for oxidative phosphorylation in Trypanosoma brucei

Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart

Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote