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List of works by Leonard C. Edelstein

Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice

scientific article

Bayesian modelling of high-throughput sequencing assays with malacoda

scientific article published on 21 July 2020

Chromatin modification and the endothelial-specific activation of the E-selectin gene.

scientific article

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race

scientific article

Design tools for MPRA experiments

scientific article published on 01 August 2018

Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial

scientific article published on 21 July 2018

Functionalization of CD36 cardiovascular disease and expression associated variants by interdisciplinary high throughput analysis

scientific article published on 25 July 2019

Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics

scientific article published on 10 May 2018

High-throughput screening uncovers a compound that activates latent HIV-1 and acts cooperatively with a histone deacetylase (HDAC) inhibitor.

scientific article

Horizontal RNA transfer goes deep: platelet consumption and microRNA utilization by vascular smooth muscle cells

scientific article published on 01 July 2019

Human genome-wide association and mouse knockout approaches identify platelet supervillin as an inhibitor of thrombus formation under shear stress

scientific article

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics.

scientific article

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP.

scientific article published on 2 March 2017

Identification of the Regulatory Elements and Target Genes of Megakaryopoietic Transcription Factor MEF2C

scientific article published on 07 February 2019

Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2.

scientific article published on 26 April 2016

Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis

scientific article

MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression

scientific article

MicroRNAs in Platelet Physiology and Function.

scientific article published on 7 March 2016

MicroRNAs in platelet production and activation

scientific article published on 19 May 2011

MicroRNAs in platelet production and activation.

scientific article published on June 2013

NF-kappa B-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bfl-1/A1

scientific article

Nuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor.

scientific article published on February 2004

Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.

scientific article

Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth

scientific article

Small RNAs as potential platelet therapeutics.

scientific article published on January 2012

TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (FcγRIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice

scientific article

The Protease-Activated Receptor 4 Ala120Thr Variant Alters Platelet Responsiveness to Low-Dose Thrombin, Protease-Activated Receptor 4 Desensitization and Is Blocked by Noncompetitive P2Y Inhibition

article

The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome.

scientific article published on 14 February 2014

The role of platelet microvesicles in intercellular communication.

scientific article published on 8 December 2016

miR-15a-5p regulates expression of multiple proteins in the megakaryocyte GPVI signaling pathway

scientific article published on 25 February 2019

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