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List of works by John E Weldon

A Recombinant Immunotoxin against the Tumor-Associated Antigen Mesothelin Reengineered for High Activity, Low Off-Target Toxicity, and Reduced Antigenicity ⬇️

scientific article published on November 6, 2012

A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer

scientific article

A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.

scientific article

A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.

scientific article published on 17 November 2011

A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice.

scientific article

Designing the furin-cleavable linker in recombinant immunotoxins based on Pseudomonas exotoxin A.

scientific article published on 3 June 2015

Glycosaminoglycans in human retinoblastoma cells: heparan sulfate, a modulator of the pigment epithelium-derived factor-receptor interactions

scientific article

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.

scientific article

Immunotoxins with decreased immunogenicity and improved activity

scientific article published on 19 April 2011

Investigation of amino acid specificity in the CydX small protein shows sequence plasticity at the functional level.

scientific article published on 18 June 2018

Pigment epithelium-derived factor binds to hyaluronan. Mapping of a hyaluronan binding site

scientific article

Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.

scientific article

Specific interactions by the N-terminal arm inhibit self-association of the AraC dimerization domain.

scientific article

Structure and properties of a truely apo form of AraC dimerization domain

scientific article

The gene ygdP, associated with the invasiveness of Escherichia coli K1, designates a Nudix hydrolase, Orf176, active on adenosine (5')-pentaphospho-(5')-adenosine (Ap5A).

scientific article published on 30 July 2001

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