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List of works by Eric Letouzé

A 17-Beta-Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease

scientific article published on 25 April 2019

A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

scientific article published on 22 September 2021

AAV2 and Hepatocellular Carcinoma

scientific article

Argininosuccinate synthase 1 and periportal gene expression in sonic hedgehog hepatocellular adenomas.

scientific article

CDKN2A homozygous deletion is associated with muscle invasion in FGFR3-mutated urothelial bladder carcinoma

scientific article published on 8 May 2012

Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition

scientific article

Combined tumor genomic profiling and exome sequencing in a breast cancer family implicates ATM in tumorigenesis: A proof of principle study

scientific article

Compliance With Hepatocellular Carcinoma Surveillance Guidelines Associated With Increased Lead-Time Adjusted Survival of Patients With Compensated Viral Cirrhosis: A Multi-Center Cohort Study

scientific article published on 03 May 2018

Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress

scientific article published in Nature Communications

DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers

scientific article published on 30 March 2015

DNA Methylation Signatures Reveal the Diversity of Processes Remodeling Hepatocellular Carcinoma Methylomes

scientific article published in 2021

DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma

scientific article published on 18 March 2015

Deciphering the molecular basis of invasiveness in Sdhb-deficient cells

scientific article published on 8 October 2015

Deletion of chromosomes 13q and 14q is a common feature of tumors with BRCA2 mutations

scientific article

Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia.

scientific article

EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype

scientific article

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

scientific article

Extra hepatic cancers are the leading cause of death in cirrhotic patients achieving HBV control or HCV eradication.

scientific article published on 16 April 2018

Genome-wide paternal uniparental disomy as a cause of Beckwith-Wiedemann syndrome associated with recurrent virilizing adrenocortical tumors

scientific article published on 03 November 2014

Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation

scientific article published on April 2014

Genotype-phenotype correlation of CTNNB1 mutations reveals different ß-catenin activity associated with liver tumor progression

scientific article published on 11 June 2016

Germline and somatic DICER1 mutations in familial and sporadic liver tumors.

scientific article published on 21 December 2016

Germline mutations in the mitochondrial 2-oxoglutarate/malate carrier SLC25A11 gene confer a predisposition to metastatic paragangliomas.

scientific article published on 5 February 2018

Hepatitis B virus integrations promote local and distant oncogenic driver alterations in hepatocellular carcinoma

scientific article published on 09 February 2021

Hepatocellular carcinoma in Mongolia delineates unique molecular traits and a mutational signature associated with environmental agents

scientific article published in 2022

Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification

scientific article published on 19 May 2017

Hypermethylator phenotype and ectopic GIP receptor in GNAS mutation-negative somatotropinomas

scientific article published on 01 May 2019

Identity by descent mapping of founder mutations in cancer using high-resolution tumor SNP data

scientific article

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

scientific article published on 06 May 2012

Integrated genomic characterization of adrenocortical carcinoma

scientific article published on 20 April 2014

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus.

scientific article

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation

scientific article published on 7 December 2016

Multi-omics analysis defines core genomic alterations in pheochromocytomas and paragangliomas

scientific article

Multi-site tumor sampling highlights molecular intra-tumor heterogeneity in malignant pleural mesothelioma

scientific article published on 14 July 2021

Mutational Processes in Hepatocellular Carcinoma: The Story of Aristolochic Acid

scientific article published on 30 April 2019

Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.

scientific article

Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis

scientific article published on 3 November 2017

Non-virological factors are drivers of Hepatocellular Carcinoma in virosuppressed Hepatitis B cirrhosis: results of ANRS CO12 CirVir cohort

scientific article published on 16 January 2019

Oncometabolites-driven tumorigenesis: From genetics to targeted therapy

scientific article

PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases

scientific article published on 09 November 2018

Palimpsest: an R package for studying mutational and structural variant signatures along clonal evolution in cancer

scientific article published on 01 October 2018

Prognostic value of viral eradication for major adverse cardiovascular events in hepatitis C cirrhotic patients

scientific article published on 07 November 2017

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

scientific article published on 24 August 2015

SDH mutations establish a hypermethylator phenotype in paraganglioma.

scientific article published on 23 May 2013

SDHBmutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma

article

SNP array profiling of childhood adrenocortical tumors reveals distinct pathways of tumorigenesis and highlights candidate driver genes

scientific article published on 26 April 2012

Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma

article

Systemic AA Amyloidosis Caused by Inflammatory Hepatocellular Adenoma

scientific article published on 01 September 2018

TCF12 is mutated in anaplastic oligodendroglioma

scientific article published on 12 June 2015

Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome

scientific article published on 14 June 2018

Unsuspected task for an old team: succinate, fumarate and other Krebs cycle acids in metabolic remodeling

scientific article published on 31 March 2014

Wild-type AAV Insertions in Hepatocellular Carcinoma Do Not Inform Debate Over Genotoxicity Risk of Vectorized AAV.

scientific article published on April 2016

[Mutations in succinate dehydrogenase and DNA methylation].

scientific article

aCNViewer: Comprehensive genome-wide visualization of absolute copy number and copy neutral variations.

scientific article published on 19 December 2017

germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structures

scientific article published on 28 March 2019