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List of works by Tomáš Ruml

A Mason-Pfizer Monkey virus Gag-GFP fusion vector allows visualization of capsid transport in live cells and demonstrates a role for microtubules

scientific article

Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds

scientific article published on March 2014

Antimicrobial Activity of Extracts of Two Native Fruits of Chile: Arrayan (Luma apiculata) and Peumo (Cryptocarya alba)

scientific article published on 25 July 2020

Antiproliferative effects of carbon monoxide on pancreatic cancer.

scientific article published on 14 January 2014

Assignment of 1H, 13C, and 15N resonances of WT matrix protein and its R55F mutant from Mason-Pfizer monkey virus.

scientific article published in April 2005

Autophagy in MCF-7 cancer cells induced by copper complexes.

scientific article published on 30 July 2016

BODIPY-based fluorescent liposomes with sesquiterpene lactone trilobolide

scientific article published on 4 July 2017

Bioprospecting of Turbinaria Macroalgae as a Potential Source of Health Protective Compounds.

scientific article

Breast cancer-associated protein--a novel binding partner of Mason-Pfizer monkey virus protease.

scientific article published on 21 March 2014

Characterization of a 1.8-kb DNA segment located upstream from the human Ha-ras protooncogene and possibly regulating its function.

scientific article published on April 1995

Characterization of pbt genes conferring increased Pb2+ and Cd2+ tolerance upon Achromobacter xylosoxidans A8.

scientific article

Cleavage of vimentin by different retroviral proteases

scientific article published on 01 May 2000

Comparison of Chemical Composition and Biological Activities of Eight <i>Selaginella</i> Species

scientific article published on 26 December 2020

Comparison of classical and affinity purification techniques of Mason-Pfizer monkey virus capsid protein: the alteration of the product by an affinity tag.

scientific article published in October 2001

Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements

scientific article published on 18 August 2019

Conserved and variable features of Gag structure and arrangement in immature retrovirus particles

scientific article published on September 2010

Cost-effective method for the preparation of uniformly labeled myristoylated proteins for NMR measurements.

scientific article published on 21 March 2014

Current Perspectives on Taxanes: Focus on Their Bioactivity, Delivery and Combination Therapy

scientific article published in 2021

Current approaches in SELEX: An update to aptamer selection technology.

scientific article published on 20 February 2015

Cytocompatibility of Ar+ plasma treated and Au nanoparticle-grafted PE

Degradation of juvenile hormone analog by soil microbial isolates.

scientific article published in July 2003

Designing Porphyrinic Covalent Organic Frameworks for the Photodynamic Inactivation of Bacteria.

scientific article published on 22 February 2018

Differences and commonalities in plasma membrane recruitment of the two morphogenetically distinct retroviruses HIV-1 and MMTV

scientific article published on 08 May 2020

Differences in antitumor effects of various statins on human pancreatic cancer.

scientific article published on March 2008

Direct evidence for intracellular anterograde co-transport of M-PMV Gag and Env on microtubules

scientific article

Does BCA3 Play a Role in the HIV-1 Replication Cycle?

scientific article published on 20 April 2018

Effect of Schiff base Cu(II) complexes on signaling pathways in HT-29 cells

scientific article published on 14 September 2016

Effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and human immunodeficiency virus.

scientific article

Effect of equal channel angular pressing on in vitro degradation of LAE442 magnesium alloy.

scientific article

Effect of the Schiff base complex diaqua-(N-salicylidene-l-glutamato)copper(II) monohydrate on human tumor cells.

scientific article published on 7 October 2013

Efficient Mutagenesis Independent of Ligation (EMILI)

scientific article published on 18 August 2014

Engineered retroviral virus-like particles for receptor targeting

scientific article published on 17 October 2013

Enhanced metallosorption of Escherichia coli cells due to surface display of beta- and alpha-domains of mammalian metallothionein as a fusion to LamB protein

scholarly article published in Journal of Receptors and Signal Transduction

Expression and purification of myristoylated matrix protein of Mason-Pfizer monkey virus for NMR and MS measurements.

scientific article

FAITH - Fast Assembly Inhibitor Test for HIV.

scientific article published on 24 September 2015

Functional and Structural Characterization of Novel Type of Linker Connecting Capsid and Nucleocapsid Protein Domains in Murine Leukemia Virus.

scientific article

Genetically modified plants in phytoremediation of heavy metal and metalloid soil and sediment pollution

scientific article published on 28 June 2009

HIV-1 protease-induced apoptosis

scientific article

Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells.

scientific article

High resolution mass spectrometry based method applicable for a wide range of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors in blood serum including intermediates and products of the cholesterol biosynthetic pathway.

scientific article published on 31 January 2017

Highly porous, low elastic modulus 316L stainless steel scaffold prepared by selective laser melting.

scientific article

Human UBL5 protein interacts with coilin and meets the Cajal bodies.

scientific article published on 30 May 2013

In vitro assembly of virus-like particles of a gammaretrovirus, the murine leukemia virus XMRV.

scientific article published on 16 November 2011

In vitro methods for testing antiviral drugs

scientific article published on 29 December 2017

Influence of surface pre-treatment on the cytocompatibility of a novel biodegradable ZnMg alloy.

scientific article published on 26 May 2016

Inhibition of HIV-1 integrase by modified oligonucleotides derived from U5' LTR.

scientific article

Inhibition of Mitochondrial Metabolism Leads to Selective Eradication of Cells Adapted to Acidic Microenvironment

scientific article published in 2021

Integrase of Mason-Pfizer monkey virus.

scientific article

Interaction of Mason-Pfizer monkey virus matrix protein with plasma membrane

scientific article published on January 2013

Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells

scientific article published on 20 December 2017

Luminometric method for screening retroviral protease inhibitors.

scientific article published in October 2005

Mapping of gene controlling thiamine transport in Saccharomyces cerevisiae

scientific article published on 01 September 1996

Mason-Pfizer Monkey Virus Envelope Glycoprotein Cycling and Its Vesicular Co-Transport with Immature Particles

scientific article published on 20 October 2018

Membrane Interactions of the Mason-Pfizer Monkey Virus Matrix Protein and Its Budding Deficient Mutants

scientific article

Metallomics for Alzheimer's disease treatment: Use of new generation of chelators combining metal-cation binding and transport properties

scientific article published on 2 March 2018

Microstructural, mechanical, corrosion and cytotoxicity characterization of the hot forged FeMn30(wt.%) alloy

scientific article published on 12 September 2015

Mitotic Poisons in Research and Medicine

scientific article published on 12 October 2020

Molecular aspects of the interaction between Mason-Pfizer monkey virus matrix protein and artificial phospholipid membrane.

scientific article published on 31 August 2016

Molecular organization of Mason-Pfizer monkey virus capsids assembled from Gag polyprotein in Escherichia coli.

scientific article

Mutations in the Basic Region of the Mason-Pfizer Monkey Virus Nucleocapsid Protein Affect Reverse Transcription, Genomic RNA Packaging, and the Virus Assembly Site

scientific article published on 28 February 2018

NMR structure of the N-terminal domain of capsid protein from the mason-pfizer monkey virus

scientific article

Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging.

scientific article published on 24 February 2016

Oligomerization of a Retroviral Matrix Protein Is Facilitated by Backbone Flexibility on Nanosecond Time Scale ⬇️

scientific article published on March 2, 2011

One-step separation of myristoylated and nonmyristoylated retroviral matrix proteins.

scientific article published on 19 September 2013

Optimized method for isolation of immature intracytoplasmic retroviral particles from mammalian cells.

scientific article

PEGylated Purpurin 18 with Improved Solubility: Potent Compounds for Photodynamic Therapy of Cancer

scientific article published on 06 December 2019

PF74 and Its Novel Derivatives Stabilize Hexameric Lattice of HIV-1 Mature-Like Particles

scientific article published on 20 April 2020

PTEN sequence analysis in endometrial hyperplasia and endometrial carcinoma in Slovak women

scientific article published on 31 May 2015

Pentamethinium fluorescent probes: The impact of molecular structure on photophysical properties and subcellular localization

Phytochemical Composition and In Vitro Biological Activity of Iris spp. (Iridaceae): A New Source of Bioactive Constituents for the Inhibition of Oral Bacterial Biofilms

scientific article published on 11 July 2020

Postbiotics, Metabolic Signaling, and Cancer

scientific article published in 2021

Purification of proteins containing zinc finger domains using immobilized metal ion affinity chromatography.

scientific article

Rapid protocol for electroporation of Clostridium perfringens

scientific article published on 01 July 2005

Rational design of chemical ligands for selective mitochondrial targeting

scientific article published on 3 September 2013

Resonance assignments of the myristoylated Y28F/Y67F mutant of the Mason-Pfizer monkey virus matrix protein

scientific article

Role of Mason-Pfizer monkey virus CA-NC spacer peptide-like domain in assembly of immature particles.

scientific article published on October 2014

SUMO-2/3 conjugates accumulating under heat shock or MG132 treatment result largely from new protein synthesis.

scientific article published on 28 January 2012

Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection.

scientific article published in June 2003

Striking antitumor activity of a methinium system with incorporated quinoxaline unit obtained by spontaneous cyclization

scientific article

Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution

scientific article

Structure of the immature retroviral capsid at 8 Å resolution by cryo-electron microscopy

scientific article

Structure, mechanical characteristics and in vitro degradation, cytotoxicity, genotoxicity and mutagenicity of novel biodegradable Zn-Mg alloys.

scientific article published on 17 August 2015

Study of Cytotoxic Effects of Benzonitrile Pesticides

scientific article published on 3 August 2015

Surface display of metal fixation motifs of bacterial P1-type ATPases specifically promotes biosorption of Pb(2+) by Saccharomyces cerevisiae

scientific article

Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces

scientific article published on 08 August 2021

Synthesis and biological evaluation of nandrolone-bodipy conjugates.

scientific article

Tailor-made fluorescent trilobolide to study its biological relevance.

scientific article published on 17 September 2014

Targeting of stress response pathways in the prevention and treatment of cancer

scientific article published on 12 January 2018

The Current View of Retroviruses as Seen from the Shoulders of a Giant

scientific article published on 05 September 2019

The G-Patch Domain of Mason-Pfizer Monkey Virus Is a Part of Reverse Transcriptase ⬇️

scientific article published on December 14, 2011

The RNA binding G-patch domain in retroviral protease is important for infectivity and D-type morphogenesis of Mason-Pfizer monkey virus.

scientific article

The Role of the S-S Bridge in Retroviral Protease Function and Virion Maturation

scientific article published on 06 November 2006

The Structure of Myristoylated Mason-Pfizer Monkey Virus Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Its Membrane Binding ⬇️

scientific article published on August 2, 2012

The complex understanding of Annexin A1 phosphorylation

scientific article

The effect of different solvents on the ATP/ADP content and growth properties of HeLa cells

scientific article published on 01 January 1999

The effect of point mutations within the N-terminal domain of Mason-Pfizer monkey virus capsid protein on virus core assembly and infectivity.

scientific article published on 27 August 2008

The effect of simvastatin on lipid droplets accumulation in human embryonic kidney cells and pancreatic cancer cells.

scientific article published on 21 August 2013

The interplay of plasma treatment and gold coating and ultra-high molecular weight polyethylene: On the cytocompatibility.

scientific article

The irreversibility of thiamin transport in Saccharomyces cerevisiae

scientific article published on 01 January 1988

The three-dimensional solution structure of the matrix protein from the type D retrovirus, the Mason-Pfizer monkey virus, and implications for the morphology of retroviral assembly

scientific article

Three active forms of aspartic proteinase from Mason-Pfizer monkey virus.

scientific article published on June 1998

Three metallothionein isoforms and sequestration of intracellular silver in the hyperaccumulator Amanita strobiliformis

scientific article

Three-dimensional structure of a monomeric form of a retroviral protease

scientific article

Titania sol-gel coatings containing silver on newly developed TiSi alloys and their antibacterial effect.

scientific article published on 27 February 2017

Trilobolide-porphyrin conjugates: on synthesis and biological effects evaluation

scientific article

Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity.

scientific article published on 17 August 2016

Variability in statin-induced changes in gene expression profiles of pancreatic cancer.

scientific article published on 09 March 2017

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