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List of works by Alejandro Gutierrez

Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia

scientific article

Acute myeloid/T-lymphoblastic leukaemia (AMTL): a distinct category of acute leukaemias with common pathogenesis in need of improved therapy.

scientific article published on 14 February 2018

Alu elements mediate MYB gene tandem duplication in human T-ALL

scientific article published on 10 December 2007

An "off-the-shelf" fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies.

scientific article published on 20 February 2018

An X-linked tumor suppressor in T-ALL.

scientific article published in January 2015

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

scientific article published on 21 May 2007

Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.

scientific article

Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression.

scientific article published on 24 August 2009

Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia

scientific article published on 13 November 2019

Heat-shock induction of T-cell lymphoma/leukaemia in conditional Cre/lox-regulated transgenic zebrafish.

scientific article published in July 2007

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

scientific article published on 20 May 2009

Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.

scientific article

Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B.

scientific article

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

scientific article

JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.

scientific article published on 25 June 2018

Liquid chromatography-mass spectrometry (LC-MS) of steroid hormone metabolites and its applications.

scientific article

NOTCH and PI3K-AKT pathways intertwined.

scientific article published in November 2007

NOTCH1 Signaling Promotes Human T-Cell Acute Lymphoblastic Leukemia Initiating Cell Regeneration in Supportive Niches ⬇️

scientific article published on June 29, 2012

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia

article

PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis

scientific article published on 30 June 2020

Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia.

scientific article published on 09 January 2014

Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia.

scientific article

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia.

scientific article

Resolution of cerebral artery stenosis in a child with sickle cell anemia treated with hydroxyurea.

scientific article published in February 2010

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

scientific article

T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation.

scientific article

TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia

scientific article published on 7 March 2013

c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells

scientific article published on 06 January 2014

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