Search filters

List of works by Adam J. Dupuy

A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition

scientific article

A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model ⬇️

scientific article published on April 16, 2013

A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis

scientific article

A Transposon-based Analysis Reveals RASA1 Is Involved in Triple-Negative Breast Cancer

scientific article

A Trp53fl/flPtenfl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging.

scientific article

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

scientific article published on 22 February 2009

A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice

scientific article published on 06 October 2009

A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells

scientific article published on 17 June 2019

A transposon-based analysis of gene mutations related to skin cancer development.

scientific article

A transposon-based genetic screen in mice identifies genes altered in colorectal cancer

scientific article

Adaptive Immunity Does Not Strongly Suppress Spontaneous Tumors in a Sleeping Beauty Model of Cancer ⬇️

scientific article published on March 8, 2013

Cell of origin strongly influences genetic selection in a mouse model of T-ALL

scientific article published on 9 August 2011

Cell-internalization SELEX: method for identifying cell-internalizing RNA aptamers for delivering siRNAs to target cells

scientific article

Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1

scientific article published on 06 January 2012

Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.

scientific article

Clonal selection drives genetic divergence of metastatic medulloblastoma

scientific article published on 15 February 2012

Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function

scientific article

Divergent clonal selection dominates medulloblastoma at recurrence

scientific article published on 13 January 2016

Ectopic Expression of Zmiz1 Induces Cutaneous Squamous Cell Malignancies in a Mouse Model of Cancer ⬇️

scientific article published on February 20, 2013

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

scientific article

Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis

scientific article

Mammalian germ-line transgenesis by transposition.

scientific article

MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression.

scientific article

MicroRNA‐494 within an oncogenic microRNA megacluster regulates G 1 /S transition in liver tumorigenesis through suppression of mutated in colorectal cancer ⬇️

scientific article published on November 22, 2013

Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors

scientific article

Nucleotide bias observed with a short SELEX RNA aptamer library

scientific article

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

scientific article

Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens

scientific article

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

scientific article

Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer

scientific article published on 02 September 2021

Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors.

scientific article published on 9 October 2017

Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma

scientific article published on 15 March 2012

Sleeping beauty: a novel cancer gene discovery tool

scientific article

Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish

scientific article

Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal.

scientific article published on 22 September 2016

The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity

scientific article published on 18 September 2017

The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis

scientific article (publication date: 2013)

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

scientific article published in 2022

Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms

scientific article published on 28 October 2016

Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene

scientific article published on 5 June 2017

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

scientific article

Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma

scientific article published on 13 April 2015

Paulina is supported by:

About Paulina

Help