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List of works by Adam J. Dupuy

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Clonal selection drives genetic divergence of metastatic medulloblastoma

scientific article published on 15 February 2012
A transposon-based genetic screen in mice identifies genes altered in colorectal cancer

scientific article
Gene transfer into genomes of human cells by the sleeping beauty transposon system.

scientific article
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma

scientific article published on 15 March 2012
A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

scientific article published on 22 February 2009
Mammalian germ-line transgenesis by transposition.

scientific article
Divergent clonal selection dominates medulloblastoma at recurrence

scientific article published on 13 January 2016
A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice

scientific article published on 06 October 2009
MicroRNA‐494 within an oncogenic microRNA megacluster regulates G 1 /S transition in liver tumorigenesis through suppression of mutated in colorectal cancer

scientific article published on November 22, 2013
Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

scientific article
Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors

scientific article
A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis

scientific article
Cell of origin strongly influences genetic selection in a mouse model of T-ALL

scientific article published on 9 August 2011
Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis

scientific article
The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis

scientific article (publication date: 2013)
Nucleotide bias observed with a short SELEX RNA aptamer library

scientific article
Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma

scientific article published on 13 April 2015
Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

scientific article
Sleeping beauty: a novel cancer gene discovery tool

scientific article
A transposon-based analysis of gene mutations related to skin cancer development.

scientific article
Cell-internalization SELEX: method for identifying cell-internalizing RNA aptamers for delivering siRNAs to target cells

scientific article
Adaptive Immunity Does Not Strongly Suppress Spontaneous Tumors in a Sleeping Beauty Model of Cancer

scientific article published on March 8, 2013
Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal.

scientific article published on 22 September 2016
Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish

scientific article
Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function

scientific article
A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model

scientific article published on April 16, 2013
MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression.

scientific article
Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors.

scientific article published on 9 October 2017
A Transposon-based Analysis Reveals RASA1 Is Involved in Triple-Negative Breast Cancer

scientific article
RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

scientific article
Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens

scientific article
Ectopic Expression of Zmiz1 Induces Cutaneous Squamous Cell Malignancies in a Mouse Model of Cancer

scientific article published on February 20, 2013
The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity

scientific article published on 18 September 2017
Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene

scientific article published on 5 June 2017
Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms

scientific article published on 28 October 2016
Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.

scientific article
A Trp53fl/flPtenfl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging.

scientific article
Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1

scientific article published on 06 January 2012
A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition

scientific article
Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer

scientific article published on 02 September 2021
A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells

scientific article published on 17 June 2019
Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

scientific article published in 2022

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