List of works by Rachel Rau

3488 A comparison between the Rolling 6 and 3+3 dose escalation study designs for phase 1 clinical trials

scientific article published on 27 March 2019

50 Years Ago in The Journal of Pediatrics: Sequential Therapy of Acute Leukemia in Childhood.

scientific article

A KLF4-DYRK2-mediated pathway regulating self-renewal in CML stem cells

scientific article published on 01 November 2019

A phase 1 study of eribulin mesylate (E7389), a novel microtubule-targeting chemotherapeutic agent, in children with refractory or recurrent solid tumors: A Children's Oncology Group Phase 1 Consortium study (ADVL1314)

scientific article published on 02 May 2018

An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance

scientific article published on 11 September 2020

Beyond KIT in CBF-AML: chromatin and cohesin.

scientific article published in May 2016

CMML/JMML PDXs: as easy as 1, 2, NSG-SGM3.

scientific article published in July 2017

Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis

scientific article published on 30 May 2022

Cutting to the Front of the Line: Immunotherapy for Childhood Acute Lymphoblastic Leukemia

scientific article published on 01 March 2020

Cytoplasmic Nucleophosmin (NPMc+) Mutations and FMS-Like Tyrosine Kinase 3 (Flt3) Internal Tandem Duplication (ITD) Mutations Cooperate to Cause Leukemia In a Mouse Model ⬇️

scholarly article

DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias

scientific article published on 08 August 2016

DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.

scientific article published on June 2016

DNMT3A in haematological malignancies

scientific article

DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia

scientific article published on 22 June 2016

Efficacy and safety of intramuscular (IM) recombinant <i>Erwinia</i> asparaginase in acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LBL): The Children’s Oncology Group (COG) AALL1931 study.

scientific article published in 2022

Enteric gram-negative bacilli bloodstream infections: 17 years' experience in a neonatal intensive care unit

scientific article

Ethnic disparities relative to disease features and outcomes in children with acute myeloid leukemia.

scientific article

Experience with ponatinib in paediatric patients with leukaemia

scientific article published on 24 January 2020

Fatal infection caused by Cupriavidus gilardii in a child with aplastic anemia

scientific article

How the COG is Approaching the High-Risk Patient with ALL: Incorporation of Immunotherapy into Frontline Treatment

scientific article published on 01 September 2020

Impact of Race/Ethnicity on Pediatric Core Binding Factor AML Outcomes and Response to Gemtuzumab Ozogamicin

scientific article published in 2020

Incidence and predictors of treatment-related conjugated hyperbilirubinemia during early treatment phases for children with acute lymphoblastic leukemia

scientific article published on 17 November 2019

Initial Results from a Phase 2/3 Study of Recombinant Erwinia Asparaginase (JZP458) in Patients with Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL) Who Are Allergic/Hypersensitive to E. coli-Derived Asparaginases

scientific article published in 2021

Klinefelter syndrome and 47,XYY syndrome in children with B cell acute lymphoblastic leukaemia.

scientific article published on 19 July 2016

Knock-in of the R394W mutation causes MDS and cooperates with to drive aggressive myeloid neoplasms in mice

MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism

scientific article (publication date: March 2013)

Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia.

scientific article published on 15 May 2018

Measure Twice, Cut Once: Therapeutic Editing of HSPCs Requires Precise Planning

scientific article published on 01 April 2019

Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes

scientific article published on 18 May 2016

NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease

scientific article published on 29 October 2013

Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens

scientific article

Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity.

scientific article

Open-Label, Multicenter, Phase 2/3 Study of Recombinant Crisantaspase Produced in Pseudomonas Fluorescens (RC-P) in Patients with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) Following Hypersensitivity to Escherichia coli-Deriv

scientific article published in 2019

Outcome of pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma with hypersensitivity to pegaspargase treated with PEGylated Erwinia asparaginase, pegcrisantaspase: A report from the Children's Oncology Group

scientific article published in November 2017

Phase 1/2 trial of talazoparib in combination with temozolomide in children and adolescents with refractory/recurrent solid tumors including Ewing sarcoma: A Children's Oncology Group Phase 1 Consortium study (ADVL1411)

scientific article published on 14 November 2019

Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition

scientific article

Ponatinib use in two pediatric patients with relapsed Ph + ALL with ABL1 kinase domain mutations

scientific article published on 11 September 2019

Prevention of mercaptopurine-induced hypoglycemia using allopurinol to reduce methylated thiopurine metabolites

scientific article published on 13 December 2018

Recombinant <i>Erwinia</i> Asparaginase (JZP458) in Acute Lymphoblastic Leukemia: Results from the Phase 2/3 AALL1931 Study

scientific article published in 2022

SIRPAssing other xenograft murine models?

scientific article published on 01 May 2020

Sustained remission with azacitidine monotherapy and an aberrant precursor B-lymphoblast population in juvenile myelomonocytic leukemia

scientific article published on 28 June 2019

Targeting Activated Signaling Pathways for the Treatment of IKZF1-Deleted B Lymphoblastic Leukemia ⬇️

scholarly article

The genomics of acute myeloid leukemia in children

scientific article published on 01 March 2020

The incidence and clinical significance of nucleophosmin mutations in childhood AML.

scientific article published on 17 April 2007

Triad of severe abdominal pain, inappropriate antidiuretic hormone secretion, and disseminated varicella-zoster virus infection preceding cutaneous manifestations after hematopoietic stem cell transplantation: utility of PCR for early recognition an

scientific article published in March 2008

Use of Allopurinol to Mitigate 6-Mercaptopurine Associated Gastrointestinal Toxicity in Acute Lymphoblastic Leukemia

scientific article published on 16 July 2020

Using genomics to define pediatric blood cancers and inform practice

scientific article published on 01 November 2018

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