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List of works by Dung-Fang Lee

A delayed chemically induced tumorigenesis in Brca2 mutant mice

scientific article published in March 2004

A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming

scientific article

A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing.

scientific article published on 26 January 2018

AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation

scientific article published on 12 January 2016

APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis

scientific article

APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis

ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway

scientific article

Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells

scientific article

Advances in targeting IKK and IKK-related kinases for cancer therapy

scientific article published on September 2008

All roads lead to mTOR: integrating inflammation and tumor angiogenesis

scientific article published on 20 September 2007

Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.

scientific article published on April 2008

Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2

scientific article

Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency.

scientific article published on 22 March 2012

Cytoplasmic expression of p21CIP1/WAF1 is correlated with IKKbeta overexpression in human breast cancers

scientific article published on 01 November 2006

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

scientific article published on 26 March 2007

Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen

scientific article published on 22 July 2015

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

scientific article published on August 2008

E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation

scientific article

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

scientific article published on 20 January 2008

Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor

scientific article

Epigenetic roles of MLL oncoproteins are dependent on NF-κB

scientific article published on 19 September 2013

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

scientific article published in July 2005

Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.

scientific article published on 27 April 2018

Exploration of self-renewal and pluripotency in ES cells using RNAi

scientific article published on 01 January 2010

FOXO1 is an essential regulator of pluripotency in human embryonic stem cells

scientific article

FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization

scientific article published on 12 September 2011

Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation

scientific article published on 02 October 2018

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

scientific article

IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance.

scientific article published on November 2008

IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression

scientific article published on 22 December 2011

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

scientific article

KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta

scientific article published on October 2009

KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.

scientific article

Modeling familial cancer with induced pluripotent stem cells

scientific article

Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia.

scientific article published on 7 October 2015

Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.

scientific article published on 10 May 2007

Oct4 and klf4 reprogram dermal papilla cells into induced pluripotent stem cells

scientific article

Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome

scientific article published on 29 December 2021

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

scientific article

Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation

scientific article

Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients.

scientific article published on June 2004

Prdm16 is a physiologic regulator of hematopoietic stem cells.

scientific article

Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling

scientific article

Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells.

scientific article

TNFalpha induces HIF-1alpha expression through activation of IKKbeta

scientific article published on 17 September 2009

The crosstalk of mTOR/S6K1 and Hedgehog pathways

scientific article

The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription.

scientific article

Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1

scientific article

Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network

scientific journal article

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