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List of works by JoAnne Stubbe

2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase

scientific article published on 01 June 1991

2,3-difluorotyrosine at position 356 of ribonucleotide reductase R2: a probe of long-range proton-coupled electron transfer

scientific article published in September 2003

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound

scientific article published on 20 February 2018

A >200 meV Uphill Thermodynamic Landscape for Radical Transport in Escherichia coli Ribonucleotide Reductase Determined Using Fluorotyrosine-Substituted Enzymes

scientific article published on 7 October 2016

A Ferredoxin Disulfide Reductase Delivers Electrons to the Methanosarcina barkeri Class III Ribonucleotide Reductase

scientific article

A Hot Oxidant, 3-NO2Y122 Radical, Unmasks Conformational Gating in Ribonucleotide Reductase ⬇️

scientific article published on November 3, 2010

A chemically competent thiosulfuranyl radical on the Escherichia coli class III ribonucleotide reductase

scientific article

A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex

scientific article

A model for the role of multiple cysteine residues involved in ribonucleotide reduction: amazing and still confusing

scientific article published on October 13, 1992

A model of the structure of HOO-Co.bleomycin bound to d(CCAGTACTGG): recognition at the d(GpT) site and implications for double-stranded DNA cleavage.

scientific article published on May 1997

A non-heme iron protein with heme tendencies: an investigation of the substrate specificity of thymine hydroxylase

scientific article published on 01 December 1993

Accurate and rapid modeling of iron-bleomycin-induced DNA damage using tethered duplex oligonucleotides and electrospray ionization ion trap mass spectrometric analysis

scientific article

Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.

scientific article

Altered pathway routing in a class of Salmonella enterica serovar Typhimurium mutants defective in aminoimidazole ribonucleotide synthetase

scientific article

An ENDOR study of the tyrosyl free radical in ribonucleotide reductase from Escherichia coli

scientific article published in 1989

An active dimanganese(III)-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase.

scientific article

An endogenous dAMP ligand in Bacillus subtilis class Ib RNR promotes assembly of a noncanonical dimer for regulation by dATP.

scientific article published on 30 April 2018

Analysis of transient polyhydroxybutyrate production in Wautersia eutropha H16 by quantitative Western analysis and transmission electron microscopy

scientific article published on June 2005

Bacillus subtilis class Ib ribonucleotide reductase is a dimanganese(III)-tyrosyl radical enzyme

scientific article

Bacillus subtilis class Ib ribonucleotide reductase: high activity and dynamic subunit interactions.

scientific article published on 21 January 2014

Basis of dATP inhibition of RNRs.

scientific article

Bertram Clarence Cohen

scientific article published on December 18, 1971

Binding of Cob(II)alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii. Identification of dimethylbenzimidazole as the axial ligand

scientific article published on 01 March 1999

Binding site revealed of nature's most beautiful cofactor

scientific article published on December 1994

Biochemistry. The two faces of SAM

scientific article published on 01 April 2011

Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an Example

scientific article published on 08 June 2016

Biotin carboxylations--concerted or not concerted? That is the question! ⬇️

scientific article published on December 10, 1977

Bleomycin mediated degradation of DNA-RNA hybrids does not involve C-1' chemistry ⬇️

scientific article published on August 25, 1992

Bleomycins: new methods will allow reinvestigation of old issues

scientific article published on April 2004

Bleomycins: towards better therapeutics

scientific article

Catalysis and regulation. Editorial overview

scientific article

Characterization of C439SR1, a mutant of Escherichia coli ribonucleotide diphosphate reductase: evidence that C439 is a residue essential for nucleotide reduction and C439SR1 is a protein possessing novel thioredoxin-like activity

scientific article published on October 13, 1992

Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography

scientific article

Characterization of a Substrate-Derived Radical Detected during the Inactivation of Ribonucleotide Reductase from <i>Escherichia coli</i> by 2‘-Fluoromethylene-2‘-deoxycytidine 5‘-Diphosphate

scientific article published in 1998

Charge-Transfer Dynamics at the α/β Subunit Interface of a Photochemical Ribonucleotide Reductase

scientific article published on 29 December 2015

Chemical characterization of phosphoribosylamine, a substrate for newly discovered trifunctional protein containing glycineamide ribonucleotide synthetase activity

scientific article published in January 1987

Chemical specificity of pyruvate kinase from yeast ⬇️

scientific article published on March 28, 1975

Chemistry with an artificial primer of polyhydroxybutyrate synthase suggests a mechanism for chain termination

scientific article

Choosing the right metal: case studies of class I ribonucleotide reductases

scientific article

Chris Raetz, scientist and enduring friend

scientific article

Christian Raetz: scientist and friend extraordinaire

scientific article published on 7 March 2013

Circular Dichroism and Magnetic Circular Dichroism Studies of the Fully Reduced Binuclear Non-Heme Iron Active Site in the Escherichia coli R2 Subunit of Ribonucleoside Diphosphate Reductase

scientific article published in 1995

Class I ribonucleotide reductases: metallocofactor assembly and repair in vitro and in vivo.

scientific article

Class III polyhydroxybutyrate synthase: involvement in chain termination and reinitiation

scientific article published in June 2005

Clofarabine 5'-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit

scientific article

Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers

scientific article

Cloning, overproduction, and purification of the B2 subunit of ribonucleoside-diphosphate reductase

scientific article

Cloning, sequencing, and expression of the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii

scientific article published on September 1993

Coenzyme B12-dependent ribonucleotide reductase: evidence for the participation of five cysteine residues in ribonucleotide reduction

scientific article published on 01 October 1994

Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily † , ‡

scientific article

Composition and Structure of the Inorganic Core of Relaxed Intermediate X(Y122F) of Escherichia coli Ribonucleotide Reductase

scientific article published on 4 December 2015

Conformational Motions and Water Networks at the α/β Interface in E. coli Ribonucleotide Reductase

scientific article published on 06 July 2020

Conformationally Dynamic Radical Transfer within Ribonucleotide Reductase.

scientific article published on 16 October 2017

Conserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesis

scientific article

Control of metallation and active cofactor assembly in the class Ia and Ib ribonucleotide reductases: diiron or dimanganese?

scientific article published on 07 January 2011

Convergent allostery in ribonucleotide reductase.

scientific article

Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway

scientific article

Current ideas on the chemical mechanism of ribonucleotide reductases

scientific article

Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster

scientific article published on October 2010

DNA degradation by bleomycin: evidence for 2'R-proton abstraction and for C-O bond cleavage accompanying base propenal formation

scientific article published on 01 October 1986

Deciphering radical transport in the large subunit of class I ribonucleotide reductase

scientific article published on 3 January 2012

Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphate

scientific article published on 01 May 1998

Detection of covalent and noncovalent intermediates in the polymerization reaction catalyzed by a C149S class III polyhydroxybutyrate synthase

scientific article published on October 2009

Detection of intermediates from the polymerization reaction catalyzed by a D302A mutant of class III polyhydroxyalkanoate (PHA) synthase

scientific article

Determination of the in vivo stoichiometry of tyrosyl radical per betabeta' in Saccharomyces cerevisiae ribonucleotide reductase

scientific article published in October 2006

Di-iron-tyrosyl radical ribonucleotide reductases ⬇️

scientific article published on April 1, 2003

Direct Interfacial Y731 Oxidation in α2 by a Photoβ2 Subunit of E. coli Class Ia Ribonucleotide Reductase

scientific article published on 8 June 2015

Direct observation of a transient tyrosine radical competent for initiating turnover in a photochemical ribonucleotide reductase

scientific article published on 18 October 2007

Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer

scientific article published on 26 December 2018

Domain organization of Salmonella typhimurium formylglycinamide ribonucleotide amidotransferase revealed by X-ray crystallography

scientific article published on August 2004

ENDOR spectroscopy and DFT calculations: evidence for the hydrogen-bond network within α2 in the PCET of E. coli ribonucleotide reductase

scientific article published on 16 October 2012

EPR distance measurements support a model for long-range radical initiation in E. coli ribonucleotide reductase.

scientific article

EXAFS Characterization of the Intermediate X Generated During the Assembly of the <i>Escherichia coli</i> Ribonucleotide Reductase R2 Diferric Tyrosyl Radical Cofactor

scientific article published in 1998

Electron transfer reactions of fluorotyrosyl radicals

scientific article published on 01 October 2006

Enhanced subunit interactions with gemcitabine-5'-diphosphate inhibit ribonucleotide reductases.

scholarly article

Epimerization at carbon-5' of (5'R)-[5'-2H]adenosylcobalamin by ribonucleoside triphosphate reductase: cysteine 408-independent cleavage of the Co-C5' bond

scientific article published in April 2003

Equilibration of tyrosyl radicals (Y356•, Y731•, Y730•) in the radical propagation pathway of the Escherichia coli class Ia ribonucleotide reductase

scientific article

Escherichia coli class Ib ribonucleotide reductase contains a dimanganese(III)-tyrosyl radical cofactor in vivo

scientific article

Evidence for the direct transfer of the carboxylate of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to generate 4-carboxy-5-aminoimidazole ribonucleotide catalyzed by Escherichia coli PurE, an N5-CAIR mutase

scientific article (publication date: 9 March 1999)

Formal Reduction Potentials of Difluorotyrosine and Trifluorotyrosine Protein Residues: Defining the Thermodynamics of Multistep Radical Transfer.

scientific article published on 7 February 2017

Formal reduction potential of 3,5-difluorotyrosine in a structured protein: insight into multistep radical transfer

scientific article published on 22 November 2013

Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima: Structural Insights into Complex Formation † ‡

scientific article

Forward and reverse electron transfer with the Y356DOPA-beta2 heterodimer of E. coli ribonucleotide reductase.

scientific article published on 6 February 2007

Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer

scientific article published on 31 May 2013

GC/MS methods to quantify the 2-deoxypentos-4-ulose and 3'-phosphoglycolate pathways of 4' oxidation of 2-deoxyribose in DNA: application to DNA damage produced by gamma radiation and bleomycin

scientific article published on 19 October 2007

Gated Proton Release during Radical Transfer at the Subunit Interface of Ribonucleotide Reductase

scientific article published on 23 December 2020

Gemcitabine 5'-triphosphate is a stoichiometric mechanism-based inhibitor of Lactobacillus leichmannii ribonucleoside triphosphate reductase: evidence for thiyl radical-mediated nucleotide radical formation

scientific article published on 01 April 1998

Generation of a stable, aminotyrosyl radical-induced α2β2 complex of Escherichia coli class Ia ribonucleotide reductase

scientific article published on 19 February 2013

Generation of the R2 subunit of ribonucleotide reductase by intein chemistry: insertion of 3-nitrotyrosine at residue 356 as a probe of the radical initiation process

scientific article

Genetic characterization and role in virulence of the ribonucleotide reductases of Streptococcus sanguinis

scientific article published on 31 December 2013

Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase

scientific article published on 19 January 2017

Glutamate 52-β at the α/β subunit interface of Escherichia coli class Ia ribonucleotide reductase is essential for conformational gating of radical transfer

scientific article published on 4 April 2017

Glycinamide ribonucleotide synthetase from Escherichia coli: cloning, overproduction, sequencing, isolation, and characterization [Erratum to document cited in CA112(5):31307r]

scientific article published in 1990

Growth and localization of polyhydroxybutyrate granules in Ralstonia eutropha

scientific article

High-field EPR detection of a disulfide radical anion in the reduction of cytidine 5'-diphosphate by the E441Q R1 mutant of Escherichia coli ribonucleotide reductase

scientific article published on August 1999

High-field pulsed electron-electron double resonance spectroscopy to determine the orientation of the tyrosyl radicals in ribonucleotide reductase

scholarly article

High-frequency (139.5 GHz) EPR spectroscopy of the tyrosyl radical in Escherichia coli ribonucleotide reductase

scientific article published in 1993

High-frequency 180 GHz PELDOR

article published in 2005

Hydrogen bond network between amino acid radical intermediates on the proton-coupled electron transfer pathway of E. coli α2 ribonucleotide reductase

scientific article published on 29 December 2014

Identification of protonated oxygenic ligands of ribonucleotide reductase intermediate X.

scientific article published on March 2009

Identification of two alpha-ketoglutarate-dependent dioxygenases in extracts of Rhodotorula glutinis catalyzing deoxyuridine hydroxylation

scientific article (publication date: 25 August 1985)

Immunocytochemical analysis of poly-beta-hydroxybutyrate (PHB) synthase in Alcaligenes eutrophus H16: localization of the synthase enzyme at the surface of PHB granules

scientific article

Importance of the maintenance pathway in the regulation of the activity of Escherichia coli ribonucleotide reductase

scientific article published on 4 March 2008

In vitro analysis of the chain termination reaction in the synthesis of poly-(R)-beta-hydroxybutyrate by the class III synthase from Allochromatium vinosum

scientific article published in July 2005

Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical.

scientific article published on February 2010

Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: covalent modification

scientific article

Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase

scientific article published on 21 September 2011

Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant

scientific article published on December 2009

Interaction of 3'-[3H]2'-Chloro-2'-deoxyuridine 5'-triphosphate with ribonucleotide reductase from Lactobacillus leichmannii ⬇️

scientific article published on February 10, 1983

Interaction of C225SR1 mutant subunit of ribonucleotide reductase with R2 and nucleoside diphosphates: tales of a suicidal enzyme

scientific article published on October 13, 1992

Investigation of in vivo diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2 protein: requirement of Rnr4 and contribution of Grx3/4 AND Dre2 proteins

scientific article published on 19 September 2011

Investigation of in vivo roles of the C-terminal tails of the small subunit (ββ') of Saccharomyces cerevisiae ribonucleotide reductase: contribution to cofactor formation and intersubunit association within the active holoenzyme

scientific article published on 25 March 2013

Isolation of a multifunctional protein with aminoimidazole ribonucleotide synthetase, glycinamide ribonucleotide synthetase, and glycinamide ribonucleotide transformylase activities: characterization of aminoimidazole ribonucleotide synthetase

scientific article published on 01 July 1986

Isotope effects on the cleavage of DNA by bleomycin: Mechanism and modulation ⬇️

scientific article published on March 16, 1993

Kinetic studies of polyhydroxybutyrate granule formation in Wautersia eutropha H16 by transmission electron microscopy

scientific article published on June 2005

Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine-Substituted Escherichia coli Ribonucleotide Reductases

scientific article

Kinetics of hydrogen atom abstraction from substrate by an active site thiyl radical in ribonucleotide reductase

scientific article

Location of the redox-active thiols of ribonucleotide reductase: sequence similarity between the Escherichia coli and Lactobacillus leichmannii enzymes

scientific article published on 01 November 1987

Mapping the subunit interface of ribonucleotide reductase (RNR) using photo cross-linking

scientific article published on 19 August 2008

Mechanism of Assembly of the Diferric Cluster−Tyrosyl Radical Cofactor of <i>Escherichia coli</i> Ribonucleotide Reductase from the Diferrous Form of the R2 Subunit

scientific article published in 1996

Mechanism of assembly of the dimanganese-tyrosyl radical cofactor of class Ib ribonucleotide reductase: enzymatic generation of superoxide is required for tyrosine oxidation via a Mn(III)Mn(IV) intermediate

scientific article published on 27 February 2013

Mechanism of bleomycin: evidence for 4'-ketone formation in poly(dA-dU) associated exclusively with free base release

scientific article published on 01 December 1985

Mechanism of bleomycin: evidence for a rate-determining 4'-hydrogen abstraction from poly(dA-dU) associated with the formation of both free base and base propenal

scientific article published on 01 December 1985

Mechanism of inactivation of Escherichia coli and Lactobacillus leichmannii ribonucleotide reductases by 2'-chloro-2'-deoxynucleotides: evidence for generation of 2-methylene-3(2H)-furanone

scientific article published on 01 October 1984

Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphate

scientific article

Mechanism-based inactivation of thymine hydroxylase, an alpha-ketoglutarate-dependent dioxygenase, by 5-ethynyluracil

scientific article published on 01 December 1993

Mechanism-based inhibition of a mutant Escherichia coli ribonucleotide reductase (cysteine-225----serine) by its substrate CDP.

scientific article

Mechanistic analyses of site-specific degradation in DNA-RNA hybrids by prototypic DNA cleavers

scientific article published on May 1997

Mechanistic insight with HBCH2CoA as a probe to polyhydroxybutyrate (PHB) synthases

scientific article

Mechanistic studies of semicarbazone triapine targeting human ribonucleotide reductase in vitro and in mammalian cells: tyrosyl radical quenching not involving reactive oxygen species

scientific article

Mechanistic studies on bleomycin-mediated DNA damage: multiple binding modes can result in double-stranded DNA cleavage

scientific article published on 20 May 2008

Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study

scientific article

Methodology to probe subunit interactions in ribonucleotide reductases

scientific article published on December 2008

Models of transition

scientific article published in Nature

Modulation of Phenol Oxidation in Cofacial Dyads

scientific article

Modulation of Y356 photooxidation in E. coli class Ia ribonucleotide reductase by Y731 across the α2:β2 interface

scientific article published on 26 August 2013

Mono-, di-, tri-, and tetra-substituted fluorotyrosines: new probes for enzymes that use tyrosyl radicals in catalysis

scientific article published in February 2006

N 5 -CAIR Mutase:  Role of a CO 2 Binding Site and Substrate Movement in Catalysis † , ‡

scientific article

Nanosecond generation of tyrosyl radicals via laser-initiated decaging of oxalate-modified amino acids

scientific article

Neocarzinostatin-induced hydrogen atom abstraction from C-4' and C-5' of the T residue at a d(GT) step in oligonucleotides: shuttling between deoxyribose attack sites based on isotope selection effects ⬇️

scientific article published on February 26, 1991

New insight into the role of the PhaP phasin of Ralstonia eutropha in promoting synthesis of polyhydroxybutyrate

scientific article

Nontemplate-dependent polymerization processes: polyhydroxyalkanoate synthases as a paradigm

scientific article

NrdI, a flavodoxin involved in maintenance of the diferric-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase

scholarly article

Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein

scientific article

Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites

scientific article

PELDOR spectroscopy with DOPA-beta2 and NH2Y-alpha2s: distance measurements between residues involved in the radical propagation pathway of E. coli ribonucleotide reductase

scientific article published on 30 November 2007

PET Polymer Recycling

scientific article published on 19 June 2020

Photo-ribonucleotide reductase β2 by selective cysteine labeling with a radical phototrigger

scientific article published on 14 December 2011

Photoactive peptides for light-initiated tyrosyl radical generation and transport into ribonucleotide reductase.

scientific article published on 14 June 2007

Photochemical Generation of a Tryptophan Radical within the Subunit Interface of Ribonucleotide Reductase

scientific article published on 09 May 2016

Photochemical Rescue of a Conformationally Inactivated Ribonucleotide Reductase

scientific article published on 12 November 2018

Polyhydroxyalkanoate (PHA) homeostasis: the role of the PHA synthase ⬇️

scientific article published on October 1, 2003

Pre-steady-state and steady-state kinetic analysis of E. coli class I ribonucleotide reductase

scientific article published in September 2003

Properties of Site-Specifically Incorporated 3-Aminotyrosine in Proteins To Study Redox-Active Tyrosines: Escherichia coli Ribonucleotide Reductase as a Paradigm.

scientific article published on 9 April 2018

Protein Radicals in Enzyme Catalysis

scientific article published on 01 April 1998

Protein Radicals in Enzyme Catalysis. [Chem. Rev. 1998, 98, 705minus sign762

scientific article published on 01 November 1998

Proton-coupled electron transfer: the mechanistic underpinning for radical transport and catalysis in biology

scientific article

Pulsed ELDOR spectroscopy measures the distance between the two tyrosyl dadicals in the R2 subunit of the E. coli ribonucleotide reductase

scientific article

Purification and characterization of the purE, purK, and purC gene products: identification of a previously unrecognized energy requirement in the purine biosynthetic pathway

scientific article published on June 2, 1992

Purification of polyhydroxybutyrate synthase from its native organism, Ralstonia eutropha: implications for the initiation and elongation of polymer formation in vivo

scientific article published on 7 March 2012

Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly

scientific article

Radical initiation in the class I ribonucleotide reductase: long-range proton-coupled electron transfer?

scientific article

Radical transfer in E. coli ribonucleotide reductase: a NH2Y731/R411A-α mutant unmasks a new conformation of the pathway residue 731.

scientific article

Radicals with a controlled lifestyle ⬇️

scientific article published on October 21, 2003

Ralstonia eutropha H16 encodes two and possibly three intracellular Poly[D-(-)-3-hydroxybutyrate] depolymerase genes

scientific article

Rapid Freeze−Quench ENDOR of the Radical X Intermediate of <i>Escherichia coli</i> Ribonucleotide Reductase Using <sup>17</sup>O<sub>2</sub>, H<sub>2</sub><sup>17</sup>O, and <sup>2</sup>H<sub>2</sub>O

scientific article published in 1996

Re(bpy)(CO)3CN as a probe of conformational flexibility in a photochemical ribonucleotide reductase

scientific article published in June 2009

Redox-linked changes to the hydrogen-bonding network of ribonucleotide reductase β2.

scientific article

Redox-linked structural changes in ribonucleotide reductase

scientific article published on June 2009

Replacement of Y730 and Y731 in the alpha2 subunit of Escherichia coli ribonucleotide reductase with 3-aminotyrosine using an evolved suppressor tRNA/tRNA-synthetase pair

scientific article

Reverse Electron Transfer Completes the Catalytic Cycle in a 2,3,5-Trifluorotyrosine-Substituted Ribonucleotide Reductase

scientific article published on 22 October 2015

Reversible, long-range radical transfer in E. coli class Ia ribonucleotide reductase

scientific article

Ribonucleotide Reductases: Structure, Chemistry, and Metabolism Suggest New Therapeutic Targets

scientific article published on 01 June 2020

Ribonucleotide reductases

scientific article published on 01 January 1990

Ribonucleotide reductases in the twenty-first century

scientific article

Ribonucleotide reductases: radical enzymes with suicidal tendencies

scientific article published on 01 December 1995

Selenocysteine Substitution in a Class I Ribonucleotide Reductase

scientific article published on 06 December 2019

Self‐management of oral anticoagulation: long‐term results ⬇️

scientific article published on 01 November 2003

Sequence-specific isotope effects on the cleavage of DNA by bleomycin

scientific article

Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of p K a Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase

scientific article

Site-specific incorporation of fluorotyrosines into the R2 subunit of E. coli ribonucleotide reductase by expressed protein ligation

scientific article published in January 2007

Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation

scientific article published on 9 November 2007

Site-specific replacement of Y356 with 3,4-dihydroxyphenylalanine in the beta2 subunit of E. coli ribonucleotide reductase

scientific article published in March 2006

Site-specific replacement of a conserved tyrosine in ribonucleotide reductase with an aniline amino acid: a mechanistic probe for a redox-active tyrosine

scientific article published in December 2004

Solution structure of Co(III)-bleomycin-OOH bound to a phosphoglycolate lesion containing oligonucleotide: implications for bleomycin-induced double-strand DNA cleavage

scientific article

Solution structure of an oligonucleotide containing an abasic site: evidence for an unusual deoxyribose conformation

scientific article

Solution structure of the hydroperoxide of Co(III) phleomycin complexed with d(CCAGGCCTGG)2: evidence for binding by partial intercalation

scientific article

Spectroscopic Evidence for a H Bond Network at Y356 Located at the Subunit Interface of Active E. coli Ribonucleotide Reductase

scientific article published on 22 June 2017

Streptococcus sanguinis Class Ib Ribonucleotide Reductase

scientific article

Structural Basis for Activation of Class Ib Ribonucleotide Reductase

scientific article

Structural examination of the transient 3-aminotyrosyl radical on the PCET pathway of E. coli ribonucleotide reductase by multifrequency EPR spectroscopy

scientific article published in November 2009

Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase

scientific article

Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex

scientific article

Structure of the Catalytic Domain of the Class I Polyhydroxybutyrate Synthase from Cupriavidus necator.

scientific article

Structure of the nitrogen-centered radical formed during inactivation of E. coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine-5'-diphosphate: trapping of the 3'-ketonucleotide

scientific article published in June 2005

Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase.

scientific article published on January 2009

Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer

scientific article

Structures of the yeast ribonucleotide reductase Rnr2 and Rnr4 homodimers

scientific article

Studies on the catalysis of carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: evidence for concerted carbon-cobalt bond homolysis and thiyl radical formation

scientific article published on 01 January 1999

Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways

scientific article

Substrate specificity of formylglycinamidine synthetase

scientific article published on 01 April 1986

Subunit Interaction Dynamics of Class Ia Ribonucleotide Reductases: In Search of a Robust Assay

scientific article published on 30 March 2020

Synthesis and characterization of oligonucleotides containing a 4'-keto abasic site

scientific article

Synthesis, characterization and solution structure of tethered oligonucleotides containing an internal 3'-phosphoglycolate, 5'-phosphate gapped lesion

scientific article

Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase

scientific article

The Dimanganese(II) Site of Bacillus subtilis Class Ib Ribonucleotide Reductase

scientific article

The Ralstonia eutropha PhaR protein couples synthesis of the PhaP phasin to the presence of polyhydroxybutyrate in cells and promotes polyhydroxybutyrate production

scientific article published on January 2002

The active form of the Saccharomyces cerevisiae ribonucleotide reductase small subunit is a heterodimer in vitro and in vivo

scientific article

The class III ribonucleotide reductase from Neisseria bacilliformis can utilize thioredoxin as a reductant

scientific article

The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer

scientific article

The diferric-tyrosyl radical cluster of ribonucleotide reductase and cytosolic iron-sulfur clusters have distinct and similar biogenesis requirements

scientific article published on 17 May 2017

The formylglycinamide ribonucleotide amidotransferase complex from Bacillus subtilis: metabolite-mediated complex formation

scientific journal article

The function of adenosylcobalamin in the mechanism of ribonucleoside triphosphate reductase from Lactobacillus leichmannii

article published in 1998

The mechanism of Lactobacillus leichmannii ribonucleotide reductase. Evidence for 3' carbon-hydrogen bond cleavage and a unique role for coenzyme B12.

scientific article published in March 1986

Thermodynamic and kinetic studies on carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: the importance of entropy in catalysis

scientific article published on 01 January 1999

Thiyl radicals in ribonucleotide reductases.

scientific article

Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily

scientific article

Transcriptional analysis of Ralstonia eutropha genes related to poly-(R)-3-hydroxybutyrate homeostasis during batch fermentation.

scientific article

Turning on ribonucleotide reductase by light-initiated amino acid radical generation

scientific article

Unnatural amino acids: better than the real things?

scientific article published on 26 November 2009

Use of 2,3,5-F(3)Y-β2 and 3-NH(2)Y-α2 to study proton-coupled electron transfer in Escherichia coli ribonucleotide reductase

scientific article

Use of 3-aminotyrosine to examine the pathway dependence of radical propagation in Escherichia coli ribonucleotide reductase

scientific article published on December 2009

X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution

scientific article

X-ray crystal structure of glycinamide ribonucleotide synthetase from Escherichia coli

scientific article

YfaE, a ferredoxin involved in diferric-tyrosyl radical maintenance in Escherichia coli ribonucleotide reductase.

scientific article published on 20 September 2007

pH Dependence of charge transfer between tryptophan and tyrosine in dipeptides

scientific article

pH Rate profiles of FnY356-R2s (n = 2, 3, 4) in Escherichia coli ribonucleotide reductase: evidence that Y356 is a redox-active amino acid along the radical propagation pathway

scientific article published in February 2006

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