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List of works by Roberta Maestro

A "twist box" code of p53 inactivation: twist box: p53 interaction promotes p53 degradation

scientific article

A coordinated proto-oncogene expression characterizes MCF 247 murine leukemia virus-induced T-cell lymphomas irrespectively of proviral insertion affecting myc loci.

scientific article published in January 1990

A p53/miR-30a/ZEB2 axis controls triple negative breast cancer aggressiveness.

scientific article published on 17 April 2018

A proinflammatory cytokine inhibits p53 tumor suppressor activity

scientific article

Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis

scientific article published on May 2003

Activity of sunitinib in extraskeletal myxoid chondrosarcoma

scientific article published on 02 April 2014

All-trans, 13-cis and 9-cis retinoic acids induce a fully reversible growth inhibition in HNSCC cell lines: implications for in vivo retinoic acid use.

scientific article published on January 1997

An improved sequencing-based strategy to estimate locus-specific DNA methylation.

scientific article published on 21 September 2015

Analysis of the B-RafV600E mutation in cutaneous melanoma patients with occupational sun exposure

scientific article published on 14 January 2014

Analysis of thep53 gene in relation to tobacco and alcohol in cancers of the upper aero-digestive tract

article

Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients

scientific article published on 01 September 2010

BRACking news on triple-negative/basal-like breast cancers: how BRCA1 deficiency may result in the development of a selective tumor subtype ⬇️

scientific article published on June 1, 2012

BRCA1 modulates the expression of hnRNPA2B1 and KHSRP.

scientific article

CDC25A protein stability represents a previously unrecognized target of HER2 signaling in human breast cancer: implication for a potential clinical relevance in trastuzumab treatment.

scientific article published on June 2013

Case report: long-term survival of an infant syndromic patient affected by atypical teratoid-rhabdoid tumor

scientific article

Caspase activation and apoptosis in response to proteasome inhibitors.

scientific article published in September 2005

Concomitant mutation and epimutation of the MLH1 gene in a Lynch syndrome family

scientific article published on 05 March 2015

Constitutive overexpression of CDC25A in primary human mammary epithelial cells results in both defective DNA damage response and chromosomal breaks at fragile sites

scientific article

Coordinated expression and amplification of the MDM2, CDK4, and HMGI-C genes in atypical lipomatous tumours

scientific article published on 01 April 2000

Correction to: A p53/miR-30a/ZEB2 axis controls triple negative breast cancer aggressiveness

scientific article published on 01 November 2019

Correlation between chromosome 5q deletions and different mechanisms of c-myc overexpression in human colorectal cancer.

scientific article published on February 1991

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

scientific article published on 09 September 2021

Expression of the mdr1 gene in human colorectal carcinomas: relationship with multidrug resistance inferred from analysis of human colorectal carcinoma cell lines

scientific article published on January 1992

Extraskeletal Myxoid Chondrosarcoma: State of the Art and Current Research on Biology and Clinical Management

scientific article published on 21 September 2020

Genetic abnormalities during transition from Helicobacter-pylori-associated gastritis to low-grade MALToma

scientific article published on 01 March 1995

Identification of targets of Twist1 transcription factor in thyroid cancer cells.

scientific article

Imatinib-Sensitizing KIT Mutation in a Carney-Stratakis-Associated GI Stromal Tumor.

scientific article published on 29 December 2014

Immunophenotypic and molecular analyses of acquired immune deficiency syndrome-related and Epstein-Barr virus-associated lymphomas: a comparative study

scientific article published on February 1996

Improved outcome with multimodal treatment and imatinib rechallenge in advanced GIST

scientific article published on 15 February 2014

In K562 leukemia cells treated with doxorubicin and hemin, a decrease in c-myc mRNA expression correlates with loss of self-renewal capability but not with erythroid differentiation

scientific article

In silico prediction of physical protein interactions and characterization of interactome orphans

scientific article

In vitro and in silico studies of MDM2/MDMX isoforms predict Nutlin-3A sensitivity in well/de-differentiated liposarcomas.

scientific article published on 9 September 2013

In vivo phenotypic characteristics of AKR T-cell lymphomas with different leukemic potential: Possible role of α4β7 integrin in the progression towards the leukemic phenotype

scientific article published on 01 February 1994

Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

scientific article

KIT, PDGFRA, and BRAF mutational spectrum impacts on the natural history of imatinib-naive localized GIST: a population-based study

scientific article published on July 2015

Loss of heterozygosity at 10q in tumors of the upper respiratory tract is associated with poor prognosis

scientific article published on 01 August 1999

MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation

scientific article

MUTYH c.933+3A>C, associated with a severely impaired gene expression, is the first Italian founder mutation in MUTYH-Associated Polyposis

scientific article

MaRX: an approach to genetics in mammalian cells.

scientific article

Mesenchymal traits are selected along with stem features in breast cancer cells grown as mammospheres

scientific article

Microsatellite instability in squamous cell carcinomas of the head and neck related to field cancerization phenomena.

scientific article

Molecular abnormalities of the p53 pathway in dedifferentiated liposarcoma

scientific article published on 01 January 1997

Molecular and clinicopathologic characterization of gastrointestinal stromal tumors (GISTs) of small size

scientific article published in October 2010

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

scientific article published on 19 June 2013

Multiple Primary Sporadic Gastrointestinal Stromal Tumors in the Adult: An Underestimated Entity

scientific article published on 08 September 2008

NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas

scientific article published on 14 May 2019

Neurofibromin C terminus-specific antibody (clone NFC) is a valuable tool for the identification of NF1-inactivated GISTs.

scientific article

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

scientific article (publication date: 30 November 2006)

Other targetable sarcomas

scientific article

Overexpression of TWIST2 correlates with poor prognosis in head and neck squamous cell carcinomas.

scientific article published on December 2011

Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysis

scientific article

Premature senescence is a major response to DNA cross-linking agents in BRCA1-defective cells: implication for tailored treatments of BRCA1 mutation carriers.

scientific article published on April 2009

Prognostic determinants in epithelioid sarcoma.

scientific article published in January 2011

Proto-oncogene allelic variations in human squamous cell carcinomas of the larynx

scientific article published on 01 January 1991

Recurrences and second primary tumours in the head and neck region: differentiation by p53 mutation analysis

scientific article published on 01 November 1995

Retinoic acid stabilizes p27Kip1 in EBV-immortalized lymphoblastoid B cell lines through enhanced proteasome-dependent degradation of the p45Skp2 and Cks1 proteins.

scientific article published in April 2005

Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).

scientific article

SMARCB1/INI1 genetic inactivation is responsible for tumorigenic properties of epithelioid sarcoma cell line VAESBJ.

scientific article published on 10 April 2013

Spontaneous mutation of cell oncogenes plays a minor role in neoplastic transformation of virus-induced murine T-cell lymphomas.

scientific article published in July 1995

Sunlight and melanoma: an answer from MTS1 (p16)

scientific article

TWIST1 plays a pleiotropic role in determining the anaplastic thyroid cancer phenotype

scientific article published on 9 March 2011

The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB

scientific article published on 12 January 2009

The availability of a recombinant anti-SNAP antibody in VHH format amplifies the application flexibility of SNAP-tagged proteins

scientific article

Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing

scientific article published on 09 September 2021

Transcriptome sequencing identifies ETV6-NTRK3 as a gene fusion involved in GIST.

scientific article published on 26 November 2015

Transformation of normal human cells in the absence of telomerase activation

scientific article

Twist is a potential oncogene that inhibits apoptosis

scientific article

Twist is substrate for caspase cleavage and proteasome-mediated degradation.

scientific article published on February 2006

[Oncogenes and tumor suppressor genes in head and neck squamous cell carcinomas]

scientific article published on 01 June 1996

[Possible role of viral agents in the pathogenesis of squamous cell carcinomas of the head and neck]

scientific article published on 01 June 1996

c-myc overexpression is a tumor-specific phenomenon in a subset of human colorectal carcinomas

scientific article published on January 1990

miR-135a Inhibits Cancer Stem Cell-Driven Medulloblastoma Development by Directly Repressing Arhgef6 Expression

scientific article published in May 2015

p16/CDKN2 andCDK4 gene mutations in sporadic melanoma development and progression

scientific article published on 01 February 1997

p53 over-expression is an early event in the development of human squamous-cell carcinoma of the larynx: Genetic and prognostic implications

article

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