List of works - Hajime Watanabe

A 5' UTR-Overlapping LncRNA Activates the Male-Determining Gene doublesex1 in the Crustacean Daphnia magna

scientific article published on 24 May 2018

A murine model of atopic dermatitis can be generated by painting the dorsal skin with hapten twice 14 days apart.

scientific article published on 16 April 2018

A novel dual lock method for down-regulation of genes, in which a target mRNA is captured at 2 independent positions by linked locked nucleic acid antisense oligonucleotides

scientific article published on 18 February 2016

Analysis of expressed sequence tags of the water flea Daphnia magna.

scientific article published on August 2005

Application of ecotoxicogenomics for studying endocrine disruption in vertebrates and invertebrates.

scientific article published on April 2006

Assignment of the E4TF1-60 gene to human chromosome 21q21.2-q21.3.

scientific article

Betaproteobacteria Limnohabitans strains increase fecundity in the crustacean Daphnia magna: symbiotic relationship between major bacterioplankton and zooplankton in freshwater ecosystem.

scientific article published on 27 May 2015

CELF1 represses Doublesex1 expression via its 5’ UTR in the crustacean Daphnia magna

scientific article published on 14 October 2022

CRISPR/Cas-mediated knock-in via non-homologous end-joining in the crustacean Daphnia magna.

scientific article published on 18 October 2017

CRISPR/Cas-mediated targeted mutagenesis in Daphnia magna

scientific article

Caloric restriction upregulates the expression of DNMT3.1, lacking the conserved catalytic domain, in Daphnia magna

scientific article published on 18 November 2020

Class III Polyphosphate Kinase 2 Enzymes Catalyze the Pyrophosphorylation of Adenosine-5'-Monophosphate

scientific article published on 22 August 2019

Cloning and characterization of the ecdysone receptor and ultraspiracle protein from the water flea Daphnia magna.

scientific article published in April 2007

Co-option of the bZIP transcription factor Vrille as the activator of Doublesex1 in environmental sex determination of the crustacean Daphnia magna

scientific article

Comparison of estrogen responsive genes in the mouse uterus, vagina and mammary gland.

scientific article published on July 2007

Construction of an in Vitro Gene Screening System of the E. coli EmrE Transporter Using Liposome Display

scientific article

DNA affinity chromatography

scientific article published on 01 January 1995

Development of a Daphnia magna DNA microarray for evaluating the toxicity of environmental chemicals.

scientific article published in April 2007

Development of a bicistronic expression system in the branchiopod crustacean Daphnia magna.

scientific article published on 31 October 2017

Development of an RNA interference method in the cladoceran crustacean Daphnia magna ⬇️

scientific article published on February 17, 2011

Developmental effects of estrogenic agents on mice, fish, and frogs: a mini-review.

scientific article

Developmental effects of perinatal exposure to bisphenol-A and diethylstilbestrol on reproductive organs in female mice.

scientific article published in March 2002

Developmental effects: oestrogen-induced vaginal changes and organotin-induced adipogenesis.

scientific article published on 29 January 2008

Differential involvement of insulin-like growth factor-I and estrogen on prolactin cells in the mouse anterior pituitary.

scientific article published on 24 June 2010

Dose-related estrogen effects on gene expression in fetal mouse prostate mesenchymal cells

scientific article

Early embryonic expression of a putative ecdysteroid-phosphate phosphatase in the water flea, Daphnia magna (Cladocera: Daphniidae).

scientific article published in January 2014

Effect of DNA supercoiling on in vitro transcription from the adenovirus early region 4.

scientific article

Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes).

scientific article published in December 2003

Effects of 17beta-estradiol, nonylphenol, and bisphenol-A on developing Xenopus laevis embryos

scientific article published on September 2004

Effects of an androgenic growth promoter 17beta-trenbolone on masculinization of Mosquitofish (Gambusia affinis affinis).

scientific article published on 13 April 2005

Effects of bisphenol A given neonatally on reproductive functions of male rats.

scientific article published on 28 November 2005

Effects of diethylstilbestrol on ovarian follicle development in neonatal mice.

scientific article published on 5 November 2008

Effects of diethylstilbestrol on programmed oocyte death and induction of polyovular follicles in neonatal mouse ovaries.

scientific article published on 24 June 2009

Effects of symbiotic bacteria on chemical sensitivity of Daphnia magna.

scientific article published on 6 March 2017

Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates

scientific article

Environmental sex determination in the branchiopod crustacean Daphnia magna: deep conservation of a Doublesex gene in the sex-determining pathway

scientific article

Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation ⬇️

scientific article published on January 4, 2011

Estrogen receptor subtypes selectively mediate female mouse reproductive abnormalities induced by neonatal exposure to estrogenic chemicals.

scientific article published on 13 September 2008

Estrogen-independent activation of erbBs signaling and estrogen receptor alpha in the mouse vagina exposed neonatally to diethylstilbestrol.

scientific article

Functional Interactions of Transcription Factor Human GA-binding Protein Subunits ⬇️

scientific article (publication date: 6 November 1998)

Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription activation

scientific article

Generation of white-eyed Daphnia magna mutants lacking scarlet function

scientific article published in PLoS ONE

Genomic integration and germline transmission of plasmid injected into crustacean Daphnia magna eggs.

scientific article

Genomic integration and ligand-dependent activation of the human estrogen receptor α in the crustacean Daphnia magna.

scientific article

Growth evaluation method by live imaging of Daphnia magna and its application to the estimation of an insect growth regulator

scientific article published in January 2015

HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b

scientific article

Heterodimeric TALENs induce targeted heritable mutations in the crustacean Daphnia magna.

scientific article

Identification of gene isoforms and their switching events between male and female embryos of the parthenogenetic crustacean Daphnia magna

scientific article published on 30 April 2024

Identification of two transcription factors that bind to specific elements in the promoter of the adenovirus early-region 4 ⬇️

scientific article published on March 1, 1988

In vitro membrane protein synthesis inside Sec translocon-reconstituted cell-sized liposomes.

scientific article published on 3 November 2016

In vitro membrane protein synthesis inside cell-sized vesicles reveals the dependence of membrane protein integration on vesicle volume.

scientific article published on 11 December 2013

Introduction of foreign DNA into the water flea, Daphnia magna, by electroporation.

scientific article published on 23 January 2010

Involvement of gonadotropins in the induction of hypertrophy-hyperplasia in the interstitial tissues of ovaries in neonatally diethylstilbestrol-treated mice.

scientific article published on 12 November 2011

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription

scientific article

Juvenile hormone agonists affect the occurrence of male Daphnia ⬇️

scientific article published on December 1, 2003

Linking molecular and population stress responses in Daphnia magna exposed to cadmium.

scientific article published in March 2008

Low dose effect of in utero exposure to bisphenol A and diethylstilbestrol on female mouse reproduction.

scientific article

Mapping the expression of the sex determining factor Doublesex1 in Daphnia magna using a knock-in reporter.

scientific article published on 2 November 2017

Microbiota inoculum composition affects holobiont assembly and host growth in Daphnia.

scientific article published on 22 March 2018

Molecular cloning and sexually dimorphic expression of DM-domain genes in Daphnia magna

scientific article published on 26 November 2007

Molecular cloning of doublesex genes of four cladocera (water flea) species.

scientific article

Molecular impact of juvenile hormone agonists on neonatal Daphnia magna.

scientific article published on 05 September 2013

Monitoring ecdysteroid activities using genetically encoded reporter gene in Daphnia magna

scientific article published on 11 July 2018

Morphological changes in Daphnia galeata induced by a crustacean terpenoid hormone and its analog ⬇️

scientific article published on January 1, 2011

Mutation of the cytochrome P450 CYP360A8 gene increases sensitivity to paraquat in Daphnia magna

scientific article published on 18 December 2020

Mutations in the tobacco mosaic virus 30-kD protein gene overcome Tm-2 resistance in tomato.

scientific article published in May 1989

Neonatal Estrogen Receptor β Is Important in the Permanent Inhibition of Epithelial Cell Proliferation in the Mouse Uterus.

scientific article published on 28 May 2015

Neonatal administration of synthetic estrogen, diethylstilbestrol to mice up-regulates inflammatory Cxclchemokines located in the 5qE1 region in the vaginal epithelium

scientific article published on 16 March 2023

Optimization of mRNA design for protein expression in the crustacean Daphnia magna.

scientific article published on 2 March 2014

Parasite-mediated selection in a natural metapopulation of Daphnia magna

scientific article published on 31 October 2019

Persistent gene expression in mouse vagina exposed neonatally to diethylstilbestrol.

scientific article

Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier.

scientific article

Production of male neonates in Daphnia magna (Cladocera, Crustacea) exposed to juvenile hormones and their analogs.

scientific article published on 13 April 2005

Production of male neonates in four cladoceran species exposed to a juvenile hormone analog, fenoxycarb.

scientific article published on 17 February 2005

Promoter analysis of the neuronal nicotinic acetylcholine receptor alpha4 gene: methylation and expression of the transgene.

scientific article published in July 1998

Reduction of histamine and enhanced spinning behavior of Daphnia magna caused by scarlet mutant

scientific article published on 21 December 2020

Regional mapping of two subunits of transcription factor E4TF1 to human chromosome

scientific article

Role of foxj1 and estrogen receptor alpha in ciliated epithelial cell differentiation of the neonatal oviduct

scientific journal article

Roles of and cross-talk between ecdysteroid and sesquiterpenoid pathways in embryogenesis of branchiopod crustacean Daphnia magna

scientific article published on 09 October 2020

Roles of disulfide linkage and calcium ion-mediated interactions in assembly and disassembly of virus-like particles composed of simian virus 40 VP1 capsid protein.

scientific article

Selective ligand purification using high-performance affinity beads.

scientific article published in March 2005

Sense-overlapping lncRNA as a decoy of translational repressor protein for dimorphic gene expression

scientific article published on 28 July 2021

Sequence Conservation and Sexually Dimorphic Expression of the Ftz-F1 Gene in the Crustacean Daphnia magna

scientific article (publication date: 2016)

Sequence divergence and expression of a transformer gene in the branchiopod crustacean, Daphnia magna.

scientific article published on 6 January 2010

Similarities and differences in uterine gene expression patterns caused by treatment with physiological and non-physiological estrogens.

scientific article

Spatial redox regulation of a critical cysteine residue of NF-kappa B in vivo.

scientific article

Symbiotic bacteria contribute to increasing the population size of a freshwater crustacean, Daphnia magna.

scientific article published on 12 February 2015

Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family

scientific article (publication date: 10 December 1999)

TALEN-mediated homologous recombination in Daphnia magna.

scientific article

TALEN-mediated knock-in via non-homologous end joining in the crustacean Daphnia magna

scientific article

TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor alpha.

scientific article published on April 2006

The estrogen-responsive adrenomedullin and receptor-modifying protein 3 gene identified by DNA microarray analysis are directly regulated by estrogen receptor

scientific article published on 01 February 2006

Tissue-specific estrogenic and non-estrogenic effects of a xenoestrogen, nonylphenol.

scientific article

Toxicogenomics and ecotoxicogenomics for studying endocrine disruption and basic biology.

scientific article published on 25 January 2007

Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation

scientific article published on 18 May 2016

Transcriptome profiling in crustaceans as a tool for ecotoxicogenomics: Daphnia magna DNA microarray

scientific article published on 28 October 2008

Tryptophan hydroxylase (TRH) loss of function mutations induce growth and behavioral defects in Daphnia magna.

scientific article published on 24 January 2018

Two Doublesex1 mutants revealed a tunable gene network underlying intersexuality in Daphnia magna

scientific article published on 31 August 2020

Variations in effects of ectosymbiotic microbes on the growth rates among different species and genotypes of <i>Daphnia</i> fed different algal diets

scientific article published on 29 December 2020

Vesnarinone Suppresses TNFα mRNA Expression by Inhibiting Valosin-Containing Protein ⬇️

scientific article published on February 7, 2013

Visualization of ecdysteroid activity using a reporter gene in the crustacean, Daphnia

scientific article published on 20 November 2013

Wnt family genes and their modulation in the ovary-independent and persistent vaginal epithelial cell proliferation and keratinization induced by neonatal diethylstilbestrol exposure in mice.

scientific article published on 21 March 2012

cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs

scientific article

List of works by Hajime Watanabe

A 5' UTR-Overlapping LncRNA Activates the Male-Determining Gene doublesex1 in the Crustacean Daphnia magna

A murine model of atopic dermatitis can be generated by painting the dorsal skin with hapten twice 14 days apart.

A novel dual lock method for down-regulation of genes, in which a target mRNA is captured at 2 independent positions by linked locked nucleic acid antisense oligonucleotides

Analysis of expressed sequence tags of the water flea Daphnia magna.

Application of ecotoxicogenomics for studying endocrine disruption in vertebrates and invertebrates.

Assignment of the E4TF1-60 gene to human chromosome 21q21.2-q21.3.

Betaproteobacteria Limnohabitans strains increase fecundity in the crustacean Daphnia magna: symbiotic relationship between major bacterioplankton and zooplankton in freshwater ecosystem.

CELF1 represses Doublesex1 expression via its 5’ UTR in the crustacean Daphnia magna

CELF1 represses Doublesex1 expression via its 5’ UTR in the crustacean Daphnia magna

CRISPR/Cas-mediated knock-in via non-homologous end-joining in the crustacean Daphnia magna.

CRISPR/Cas-mediated targeted mutagenesis in Daphnia magna

Caloric restriction upregulates the expression of DNMT3.1, lacking the conserved catalytic domain, in Daphnia magna

Class III Polyphosphate Kinase 2 Enzymes Catalyze the Pyrophosphorylation of Adenosine-5'-Monophosphate

Cloning and characterization of the ecdysone receptor and ultraspiracle protein from the water flea Daphnia magna.

Co-option of the bZIP transcription factor Vrille as the activator of Doublesex1 in environmental sex determination of the crustacean Daphnia magna

Comparison of estrogen responsive genes in the mouse uterus, vagina and mammary gland.

Construction of an in Vitro Gene Screening System of the E. coli EmrE Transporter Using Liposome Display

DNA affinity chromatography

Development of a Daphnia magna DNA microarray for evaluating the toxicity of environmental chemicals.

Development of a bicistronic expression system in the branchiopod crustacean Daphnia magna.

Development of an RNA interference method in the cladoceran crustacean Daphnia magna ⬇️

Developmental effects of estrogenic agents on mice, fish, and frogs: a mini-review.

Developmental effects of perinatal exposure to bisphenol-A and diethylstilbestrol on reproductive organs in female mice.

Developmental effects: oestrogen-induced vaginal changes and organotin-induced adipogenesis.

Differential involvement of insulin-like growth factor-I and estrogen on prolactin cells in the mouse anterior pituitary.

Dose-related estrogen effects on gene expression in fetal mouse prostate mesenchymal cells

Early embryonic expression of a putative ecdysteroid-phosphate phosphatase in the water flea, Daphnia magna (Cladocera: Daphniidae).

Effect of DNA supercoiling on in vitro transcription from the adenovirus early region 4.

Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes).

Effects of 17beta-estradiol, nonylphenol, and bisphenol-A on developing Xenopus laevis embryos

Effects of an androgenic growth promoter 17beta-trenbolone on masculinization of Mosquitofish (Gambusia affinis affinis).

Effects of bisphenol A given neonatally on reproductive functions of male rats.

Effects of diethylstilbestrol on ovarian follicle development in neonatal mice.

Effects of diethylstilbestrol on programmed oocyte death and induction of polyovular follicles in neonatal mouse ovaries.

Effects of symbiotic bacteria on chemical sensitivity of Daphnia magna.

Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates

Environmental sex determination in the branchiopod crustacean Daphnia magna: deep conservation of a Doublesex gene in the sex-determining pathway

Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation ⬇️

Estrogen receptor subtypes selectively mediate female mouse reproductive abnormalities induced by neonatal exposure to estrogenic chemicals.

Estrogen-independent activation of erbBs signaling and estrogen receptor alpha in the mouse vagina exposed neonatally to diethylstilbestrol.

Functional Interactions of Transcription Factor Human GA-binding Protein Subunits ⬇️

Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription activation

Generation of white-eyed Daphnia magna mutants lacking scarlet function

Genomic integration and germline transmission of plasmid injected into crustacean Daphnia magna eggs.

Genomic integration and ligand-dependent activation of the human estrogen receptor α in the crustacean Daphnia magna.

Growth evaluation method by live imaging of Daphnia magna and its application to the estimation of an insect growth regulator

HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b

Heterodimeric TALENs induce targeted heritable mutations in the crustacean Daphnia magna.

Identification of gene isoforms and their switching events between male and female embryos of the parthenogenetic crustacean Daphnia magna

Identification of two transcription factors that bind to specific elements in the promoter of the adenovirus early-region 4 ⬇️

In vitro membrane protein synthesis inside Sec translocon-reconstituted cell-sized liposomes.

In vitro membrane protein synthesis inside cell-sized vesicles reveals the dependence of membrane protein integration on vesicle volume.

Introduction of foreign DNA into the water flea, Daphnia magna, by electroporation.

Involvement of gonadotropins in the induction of hypertrophy-hyperplasia in the interstitial tissues of ovaries in neonatally diethylstilbestrol-treated mice.

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription

Juvenile hormone agonists affect the occurrence of male Daphnia ⬇️

Linking molecular and population stress responses in Daphnia magna exposed to cadmium.

Low dose effect of in utero exposure to bisphenol A and diethylstilbestrol on female mouse reproduction.

Mapping the expression of the sex determining factor Doublesex1 in Daphnia magna using a knock-in reporter.

Microbiota inoculum composition affects holobiont assembly and host growth in Daphnia.

Molecular cloning and sexually dimorphic expression of DM-domain genes in Daphnia magna

Molecular cloning of doublesex genes of four cladocera (water flea) species.

Molecular impact of juvenile hormone agonists on neonatal Daphnia magna.

Monitoring ecdysteroid activities using genetically encoded reporter gene in Daphnia magna

Morphological changes in Daphnia galeata induced by a crustacean terpenoid hormone and its analog ⬇️

Mutation of the cytochrome P450 CYP360A8 gene increases sensitivity to paraquat in Daphnia magna

Mutations in the tobacco mosaic virus 30-kD protein gene overcome Tm-2 resistance in tomato.

Neonatal Estrogen Receptor β Is Important in the Permanent Inhibition of Epithelial Cell Proliferation in the Mouse Uterus.

Neonatal administration of synthetic estrogen, diethylstilbestrol to mice up-regulates inflammatory Cxclchemokines located in the 5qE1 region in the vaginal epithelium

Neonatal administration of synthetic estrogen, diethylstilbestrol to mice up-regulates inflammatory Cxclchemokines located in the 5qE1 region in the vaginal epithelium

Optimization of mRNA design for protein expression in the crustacean Daphnia magna.

Parasite-mediated selection in a natural metapopulation of Daphnia magna

Persistent gene expression in mouse vagina exposed neonatally to diethylstilbestrol.

Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier.

Production of male neonates in Daphnia magna (Cladocera, Crustacea) exposed to juvenile hormones and their analogs.

Production of male neonates in four cladoceran species exposed to a juvenile hormone analog, fenoxycarb.

Promoter analysis of the neuronal nicotinic acetylcholine receptor alpha4 gene: methylation and expression of the transgene.

Reduction of histamine and enhanced spinning behavior of Daphnia magna caused by scarlet mutant

Regional mapping of two subunits of transcription factor E4TF1 to human chromosome