List of works - Leonie S. Taams

A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT)

scientific article published on 28 October 2018

Anergic T cells actively suppress T cell responses via the antigen-presenting cell

article

Anti-TNF treatment negatively regulates human CD4+ T-cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype

scientific article published on 03 December 2019

Antigen presentation by T cells versus professional antigen-presenting cells (APC): differential consequences for T cell activation and subsequent T cell-APC interactions

scientific article published on 01 May 1999

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

scientific article published on 03 July 2013

CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid

scholarly article by Jocea M R van Amelsfort et al published September 2004 in Arthritis and Rheumatism

CD4+CD25+ regulatory T cells in systemic sclerosis and other rheumatic diseases

scientific article published on July 2011

CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages.

scholarly article

CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

scientific article published in May 2004

Comparative analysis of immune cell subsets in peripheral blood from patients with periodontal disease and healthy controls

scientific article published on 21 October 2018

Contribution of the IL-17 Pathway to Psoriasis and Psoriatic Arthritis

scientific article published on August 2015

Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging

scientific article published on 10 August 2009

Delivery of miR-146a to Ly6C Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis

scientific article published on 13 November 2018

Dose-dependent induction of distinct anergic phenotypes: multiple levels of T cell anergy

scientific article published on 01 February 1999

Efficacy of birch-pollen immunotherapy on cross-reactive food allergy confirmed by skin tests and double-blind food challenges.

scientific article

Enhanced and persistent levels of interleukin (IL)-17⁺ CD4⁺ T cells and serum IL-17 in patients with early inflammatory arthritis.

scientific article published in November 2013

FAS/FAS-L dependent killing of activated human monocytes and macrophages by CD4+CD25- responder T cells, but not CD4+CD25+ regulatory T cells

scientific article published on 24 December 2011

Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.

scientific article published on 16 May 2011

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

scientific article

Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population

scientific article published on 01 April 2001

Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses

scientific article published on 10 March 2021

IKZF3/Aiolos Is Associated with but Not Sufficient for the Expression of IL-10 by CD4+ T Cells

scientific article published on 22 April 2020

IL-17 in the immunopathogenesis of spondyloarthritis

scientific article published on 01 August 2018

IL-17+ CD8+ T cells: Differentiation, phenotype and role in inflammatory disease

scientific article published on 9 May 2016

Identification of a CD4+CD25+ T?cell subset committedin vivoto suppress antigen-specific T?cell responses without additional stimulation

article

Immune regulation by CD4+CD25+ regulatory T cells: implications for transplantation tolerance

scientific article

In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

scholarly article

Induction of T cell anergy by liposomes with incorporated major histocompatibility complex (MHC) II/peptide complexes

scientific article published on 01 June 2000

Inflammation and immune resolution

Inflammatory cytokines compromise programmed cell death-1 (PD-1)-mediated T cell suppression in inflammatory arthritis through up-regulation of soluble PD-1.

scientific article

Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells

scientific article published on March 2013

Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma

scientific article

Interleukin-17 in rheumatoid arthritis: Trials and tribulations

scientific article published on 01 March 2020

Interleukin-17+CD8+ T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression

scientific article

Lack of suppressive CD4+CD25+FOXP3+ T cells in advanced stages of primary cutaneous T-cell lymphoma.

scientific article published on June 2006

Linking power Doppler ultrasound to the presence of th17 cells in the rheumatoid arthritis joint

scientific article

Mechanisms of checkpoint inhibition-induced adverse events

scientific article published on 28 January 2020

MicroRNA-155 contributes to enhanced resistance to apoptosis in monocytes from patients with rheumatoid arthritis

scientific article

Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells

scientific article published on March 2005

Neuroimmune interactions: how the nervous and immune systems influence each other

scientific article published on 01 September 2019

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

scholarly article

Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses

scientific article published on 23 June 2016

Phenotypic Analysis of IL-10-Treated Macrophages Using the Monoclonal Antibodies RFD1 and RFD7

scientific article published on 01 January 1999

Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127(low) Treg Cells in Patients With Chronic Rheumatoid Arthritis

scientific article published on 28 August 2015

Polyfunctional, Proinflammatory, Tissue-Resident Memory Phenotype and Function of Synovial Interleukin-17A+CD8+ T Cells in Psoriatic Arthritis

scientific article published on 04 February 2020

Presence, function, and regulation of IL-17F-expressing human CD4+ T cells

scientific article published on 16 January 2020

Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

scientific article published on 01 March 2007

Psoriatic arthritis.

scientific article published in July 2016

Regulatory T cells in human disease and their potential for therapeutic manipulation

scientific article

Research priorities for neuroimmunology: identifying the key research questions to be addressed by 2030

scientific article published on 29 July 2021

Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure

article

Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans

scientific article

Stress proteins as inducers and targets of regulatory T cells in arthritis

scientific article

TNF Blockade Maintains an IL-10+ Phenotype in Human Effector CD4+ and CD8+ T Cells

scientific article published on 15 February 2017

TNF-α blockade induces IL-10 expression in human CD4+ T cells

scientific article published on January 2014

The Interplay Between Monocytes/Macrophages and CD4(+) T Cell Subsets in Rheumatoid Arthritis

scientific article

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

scientific article published in Nature Communications

The dynamic co-evolution of memory and regulatory CD4+ T cells in the periphery

scientific article published on March 2007

The generation and antigen-specificity of CD4+CD25+ regulatory T cells.

scientific article published on September 2006

The peripheral generation of CD4+ CD25+ regulatory T cells

scientific article

The presence, function and regulation of IL-17 and Th17 cells in periodontitis

scientific article published on 15 April 2014

Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing

scientific article published on January 2013

Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1.

scientific article published on 7 March 2018

‘Anergic’ T cells Modulate the T-cell Activating Capacity of Antigen-presenting Cells

scientific article published on 01 June 2000

List of works by Leonie S. Taams

A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT)

Anergic T cells actively suppress T cell responses via the antigen-presenting cell

Anti-TNF treatment negatively regulates human CD4+ T-cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype

Antigen presentation by T cells versus professional antigen-presenting cells (APC): differential consequences for T cell activation and subsequent T cell-APC interactions

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid

CD4+CD25+ regulatory T cells in systemic sclerosis and other rheumatic diseases

CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages.

CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

Comparative analysis of immune cell subsets in peripheral blood from patients with periodontal disease and healthy controls

Contribution of the IL-17 Pathway to Psoriasis and Psoriatic Arthritis

Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging

Delivery of miR-146a to Ly6C Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis

Dose-dependent induction of distinct anergic phenotypes: multiple levels of T cell anergy

Efficacy of birch-pollen immunotherapy on cross-reactive food allergy confirmed by skin tests and double-blind food challenges.

Enhanced and persistent levels of interleukin (IL)-17⁺ CD4⁺ T cells and serum IL-17 in patients with early inflammatory arthritis.

FAS/FAS-L dependent killing of activated human monocytes and macrophages by CD4+CD25- responder T cells, but not CD4+CD25+ regulatory T cells

Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population

Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses

IKZF3/Aiolos Is Associated with but Not Sufficient for the Expression of IL-10 by CD4+ T Cells

IL-17 in the immunopathogenesis of spondyloarthritis

IL-17+ CD8+ T cells: Differentiation, phenotype and role in inflammatory disease

Identification of a CD4+CD25+ T?cell subset committedin vivoto suppress antigen-specific T?cell responses without additional stimulation

Immune regulation by CD4+CD25+ regulatory T cells: implications for transplantation tolerance

In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

Induction of T cell anergy by liposomes with incorporated major histocompatibility complex (MHC) II/peptide complexes

Inflammation and immune resolution

Inflammatory cytokines compromise programmed cell death-1 (PD-1)-mediated T cell suppression in inflammatory arthritis through up-regulation of soluble PD-1.

Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells

Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma

Interleukin-17 in rheumatoid arthritis: Trials and tribulations

Interleukin-17+CD8+ T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression

Lack of suppressive CD4+CD25+FOXP3+ T cells in advanced stages of primary cutaneous T-cell lymphoma.

Linking power Doppler ultrasound to the presence of th17 cells in the rheumatoid arthritis joint

Mechanisms of checkpoint inhibition-induced adverse events

MicroRNA-155 contributes to enhanced resistance to apoptosis in monocytes from patients with rheumatoid arthritis

Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells

Neuroimmune interactions: how the nervous and immune systems influence each other

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses

Phenotypic Analysis of IL-10-Treated Macrophages Using the Monoclonal Antibodies RFD1 and RFD7

Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127(low) Treg Cells in Patients With Chronic Rheumatoid Arthritis

Polyfunctional, Proinflammatory, Tissue-Resident Memory Phenotype and Function of Synovial Interleukin-17A+CD8+ T Cells in Psoriatic Arthritis

Presence, function, and regulation of IL-17F-expressing human CD4+ T cells

Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

Psoriatic arthritis.

Regulatory T cells in human disease and their potential for therapeutic manipulation

Research priorities for neuroimmunology: identifying the key research questions to be addressed by 2030

Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure

Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans

Stress proteins as inducers and targets of regulatory T cells in arthritis

TNF Blockade Maintains an IL-10+ Phenotype in Human Effector CD4+ and CD8+ T Cells

TNF-α blockade induces IL-10 expression in human CD4+ T cells

The Interplay Between Monocytes/Macrophages and CD4(+) T Cell Subsets in Rheumatoid Arthritis

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

The dynamic co-evolution of memory and regulatory CD4+ T cells in the periphery

The generation and antigen-specificity of CD4+CD25+ regulatory T cells.

The peripheral generation of CD4+ CD25+ regulatory T cells

The presence, function and regulation of IL-17 and Th17 cells in periodontitis

Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing

Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1.

‘Anergic’ T cells Modulate the T-cell Activating Capacity of Antigen-presenting Cells