List of works - Jørgen Kjems

Natural RNA circles function as efficient microRNA sponges

scientific article (publication date: 21 March 2013)

Self-assembly of a nanoscale DNA box with a controllable lid

scientific article

Circular RNA and miR-7 in cancer.

scientific article

Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer.

scientific article

Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro

scientific article (publication date: June 2009)

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system.

scientific article published on 10 July 2006

Circular RNAs: Identification, biogenesis and function.

scientific article published on 11 July 2015

Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development

scientific article

The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP.

scientific article published on 11 December 1998

The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.

scientific article published on February 2007

The hnRNP A1 protein regulates HIV-1 tat splicing via a novel intron silencer element.

scientific article published on October 2001

Comparison of circular RNA prediction tools.

scientific article

The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

scientific article published on 28 April 2009

A 5' splice site enhances the recruitment of basal transcription initiation factors in vivo.

scientific article published on February 2008

miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors

scientific article

Improved silencing properties using small internally segmented interfering RNAs

scientific article

An unusual topological structure of the HIV-1 Rev response element

scientific article published on 24 October 2013

A microRNA detection system based on padlock probes and rolling circle amplification.

scientific article published on 3 August 2006

CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain

scientific article

Mapping the RNA binding sites for human immunodeficiency virus type-1 gag and NC proteins within the complete HIV-1 and -2 untranslated leader regions.

scientific article

MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma.

scientific article

DNA origami design of dolphin-shaped structures with flexible tails

scientific article

RNA interactions in the 5' region of the HIV-1 genome

scientific article (publication date: 13 February 2004)

Novel splicing mechanism for the ribosomal RNA intron in the archaebacterium Desulfurococcus mobilis

scientific article published on 01 August 1988

The emerging landscape of circular RNA in life processes.

scientific article published on 11 August 2016

Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery.

scientific article published on 31 May 2012

A novel approach to describe a U1 snRNA binding site.

scientific article published on December 2003

Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster

scientific article

The sequence complementarity between HIV-1 5' splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA.

scientific article

MicroRNAs in epilepsy: pathophysiology and clinical utility

scientific article published on December 2016

A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export

scientific article

The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer

scientific article

Insights into circular RNA biology

scientific article published on 16 December 2016

A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds.

scientific article

In vitro interaction between human immunodeficiency virus type 1 Rev protein and splicing factor ASF/SF2-associated protein, p32

scientific article published on 26 April 1996

Biological activity and biotechnological aspects of locked nucleic acids.

scientific article published on January 2013

The strength of the HIV-1 3' splice sites affects Rev function.

scientific article

Ratjadones inhibit nuclear export by blocking CRM1/exportin 1.

scientific article published on June 2003

Ribosomal RNA introns in archaea and evidence for RNA conformational changes associated with splicing

scientific article published on January 15, 1991

SF2/ASF binds to a splicing enhancer in the third HIV-1 tat exon and stimulates U2AF binding independently of the RS domain.

scientific article

A distant cis acting intronic element induces site-selective RNA editing.

scientific article

Circular RNAs are abundantly expressed and upregulated during human epidermal stem cell differentiation

scientific article published on 28 December 2017

Inefficient spliceosome assembly and abnormal branch site selection in splicing of an HIV-1 transcript in vitro

scientific article published on 01 October 1995

Evaluating the accuracy of SHAPE-directed RNA secondary structure predictions

scientific article published on January 15, 2013

Regulated HIV-2 RNA dimerization by means of alternative RNA conformations

scientific article

Endosomal trafficking of HIV-1 gag and genomic RNAs regulates viral egress.

scientific article

Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins.

scientific article published on 20 July 2014

Construction of a 4 Zeptoliters Switchable 3D DNA Box Origami

scientific article published on 08 October 2012

siRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells.

scientific article

Dimerization and template switching in the 5' untranslated region between various subtypes of human immunodeficiency virus type 1.

scientific article

List of works by Jørgen Kjems

Natural RNA circles function as efficient microRNA sponges

Self-assembly of a nanoscale DNA box with a controllable lid

Circular RNA and miR-7 in cancer.

Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer.

Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system.

Circular RNAs: Identification, biogenesis and function.

Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development

The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP.

The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.

The hnRNP A1 protein regulates HIV-1 tat splicing via a novel intron silencer element.

Comparison of circular RNA prediction tools.

The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

A 5' splice site enhances the recruitment of basal transcription initiation factors in vivo.

miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors

Improved silencing properties using small internally segmented interfering RNAs

An unusual topological structure of the HIV-1 Rev response element

A microRNA detection system based on padlock probes and rolling circle amplification.

CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain

Mapping the RNA binding sites for human immunodeficiency virus type-1 gag and NC proteins within the complete HIV-1 and -2 untranslated leader regions.

MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma.

DNA origami design of dolphin-shaped structures with flexible tails

RNA interactions in the 5' region of the HIV-1 genome

Novel splicing mechanism for the ribosomal RNA intron in the archaebacterium Desulfurococcus mobilis

The emerging landscape of circular RNA in life processes.

Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery.

A novel approach to describe a U1 snRNA binding site.

Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster

The sequence complementarity between HIV-1 5' splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA.

MicroRNAs in epilepsy: pathophysiology and clinical utility

A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export

The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer

Insights into circular RNA biology

A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds.

In vitro interaction between human immunodeficiency virus type 1 Rev protein and splicing factor ASF/SF2-associated protein, p32

Biological activity and biotechnological aspects of locked nucleic acids.

The strength of the HIV-1 3' splice sites affects Rev function.

Ratjadones inhibit nuclear export by blocking CRM1/exportin 1.

Ribosomal RNA introns in archaea and evidence for RNA conformational changes associated with splicing

SF2/ASF binds to a splicing enhancer in the third HIV-1 tat exon and stimulates U2AF binding independently of the RS domain.

A distant cis acting intronic element induces site-selective RNA editing.

Circular RNAs are abundantly expressed and upregulated during human epidermal stem cell differentiation

Inefficient spliceosome assembly and abnormal branch site selection in splicing of an HIV-1 transcript in vitro

Evaluating the accuracy of SHAPE-directed RNA secondary structure predictions

Regulated HIV-2 RNA dimerization by means of alternative RNA conformations

Endosomal trafficking of HIV-1 gag and genomic RNAs regulates viral egress.

Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins.

Construction of a 4 Zeptoliters Switchable 3D DNA Box Origami

siRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells.

Dimerization and template switching in the 5' untranslated region between various subtypes of human immunodeficiency virus type 1.