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List of works by Nadine Darwiche

A Critical Review of Animal Models Used in Acute Myeloid Leukemia Pathophysiology

scientific article published on 13 August 2019

A journey under the sea: the quest for marine anti-cancer alkaloids

scientific article published on 23 November 2011

Anti-colon cancer effects of Salograviolide A isolated from Centaurea ainetensis.

scientific article

Antitumor Effect of the Atypical Retinoid ST1926 in Acute Myeloid Leukemia and Nanoparticle Formulation Prolongs Lifespan and Reduces Tumor Burden of Xenograft Mice

scientific article published on 15 June 2017

Antitumor activities of the synthetic retinoid ST1926 in two-dimensional and three-dimensional human breast cancer models.

scientific article published on 3 May 2017

Antitumor activity of the synthetic retinoid ST1926 on primary effusion lymphoma in vitro and in vivo models

scientific article

Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide synthesis and inhibition of glucosylceramide synthase activity

scientific article published on June 2007

Autocrine transforming growth factor alpha is dispensible for v-rasHa-induced epidermal neoplasia: potential involvement of alternate epidermal growth factor receptor ligands

scientific article published on 01 May 1995

Cell cycle modulatory and apoptotic effects of plant-derived anticancer drugs in clinical use or development

scientific article published on March 2007

Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis

scientific article published on 11 September 2015

Characterization of the components of the putative mammalian sister chromatid cohesion complex

scientific journal article

Differential growth inhibitory effects of highly oxygenated guaianolides isolated from the Middle Eastern indigenous plant Achillea falcata in HCT-116 colorectal cancer cells.

scientific article published on 15 July 2013

Epigenetic mechanisms and the hallmarks of cancer: an intimate affair

scientific article published on 01 July 2020

Epigenetic mechanisms of plant-derived anticancer drugs

scientific article published on January 2012

Expression of cornifin in squamous differentiating epithelial tissues, including psoriatic and retinoic acid-treated skin

scientific article published on 01 September 1993

Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.

scientific article published on 21 May 2007

Genome-wide gene expression changes in the normal-appearing airway during the evolution of smoking-associated lung adenocarcinoma.

scientific article

Hollow-fiber membrane bioreactor for the treatment of high-strength landfill leachate.

scientific article published on 15 July 2013

Human T-cell lymphotropic virus type I-transformed T-cells have a partial defect in ceramide synthesis in response to N-(4-hydroxyphenyl)retinamide

scientific article

Identification of several mutations in ATP2C1 in Lebanese families: insight into the pathogenesis of Hailey-Hailey disease

scientific article

Inhibition of mammalian target of rapamycin signaling by everolimus induces senescence in adult T-cell leukemia/lymphoma and apoptosis in peripheral T-cell lymphomas

scientific article published on 9 December 2010

Inhibition of tumor promotion by parthenolide: epigenetic modulation of p21.

scientific article published on 4 October 2012

Lessons learned from the discovery and development of the sesquiterpene lactones in cancer therapy and prevention

scientific article published in 2022

Loss of retinoic acid receptors in mouse skin and skin tumors is associated with activation of the ras(Ha) oncogene and high risk for premalignant progression.

scientific article published on November 1996

Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase α.

scientific article published in January 2018

Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes.

scientific article published in April 2004

Mouse Models That Enhanced Our Understanding of Adult T Cell Leukemia

scientific article published on 28 March 2018

Mouse skin tumor progression results in differential expression of retinoic acid and retinoid X receptors.

scientific article published on July 1995

N-(4-hydroxyphenyl)retinamide induces growth arrest and apoptosis in HTLV-I-transformed cells

scientific article published on March 2004

Natural and synthetic retinoids in preclinical colorectal cancer models

scientific article published on 01 August 2019

Novel adamantyl retinoid-related molecules with POLA1 inhibitory activity

scientific article published on 02 September 2020

Novel therapeutic strategies for spinal osteosarcomas

scientific article published on 29 May 2019

Overexpression of retinoic acid receptors alpha and gamma into neoplastic epidermal cells causes retinoic acid-induced growth arrest and apoptosis ⬇️

scientific article published on December 1, 2001

Parthenolide: from plant shoots to cancer roots

scientific article published on 17 May 2013

Preclinical efficacy of the synthetic retinoid ST1926 for treating adult T-cell leukemia/lymphoma

scientific article

Protective effect of vitamin E on ultraviolet B light-induced damage in keratinocytes

scientific article

Purified salograviolide A isolated from centaurea ainetensis causes growth inhibition and apoptosis in neoplastic epidermal cells

scientific article

Regulation of ultraviolet B radiation-mediated activation of AP1 signaling by retinoids in primary keratinocytes.

scientific article published on March 2005

Restoration of ceramide de novo synthesis by the synthetic retinoid ST1926 as it induces adult T-cell leukemia cell death

scientific article published on 13 October 2020

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells

scientific article published on 23 March 2015

Retinoic acid down-regulation of fibronectin and retinoic acid receptor alpha proteins in NIH-3T3 cells. Blocks of this response by ras transformation

scientific article published on March 1996

Retinoic acid dramatically enhances the arsenic trioxide-induced cell cycle arrest and apoptosis in retinoic acid receptor alpha-positive human T-cell lymphotropic virus type-I-transformed cells.

scientific article published in January 2001

Retinoic acid dramatically enhances the arsenic trioxide-induced cell cycle arrest and apoptosis in retinoic acid receptor α-positive human T-cell lymphotropic virus type-I-transformed cells

Retinoid status and the control of keratin expression and adhesion during the histogenesis of squamous metaplasia of tracheal epithelium ⬇️

scientific article published on November 15, 1992

Retinoid status controls the appearance of reserve cells and keratin expression in mouse cervical epithelium ⬇️

scientific article published on May 15, 1993

Retinoids: a journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effects.

scientific article published on 20 March 2017

ST1926, an orally active synthetic retinoid, induces apoptosis in chronic myeloid leukemia cells and prolongs survival in a murine model.

scientific article

Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells

scientific article

Specificity of retinoid receptor gene expression in mouse cervical epithelia.

scientific article

Spinal sarcomas and immunity: An undervalued relationship

scientific article published on 26 June 2019

Stage-specific effect of N-(4-hydroxyphenyl)retinamide on cell growth in squamous cell carcinogenesis.

scientific article published on May 2004

Structure-activity relationship of seco-tanapartholides isolated from Achillea falcata for inhibition of HaCaT cell growth

scientific article

Synergistic anticancer activities of the plant-derived sesquiterpene lactones salograviolide A and iso-seco-tanapartholide

scientific article published on 14 September 2012

Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma

scientific article published on 01 October 1994

The high-risk benign tumor: evidence from the two-stage skin cancer model and relevance for human cancer

scientific article published on August 2007

The synthetic retinoid ST1926 as a novel therapeutic agent in rhabdomyosarcoma

scientific article published on 9 October 2015

The synthetic retinoid ST1926 attenuates prostate cancer growth and potentially targets prostate cancer stem-like cells

scientific article published on 18 March 2019

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells

scientific article published on 04 August 2020

Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion.

scientific article published on April 1998

Vitamin A in epithelial differentiation and skin carcinogenesis.

scientific article

What made sesquiterpene lactones reach cancer clinical trials?

scientific article

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