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List of works by Tatsuhiko Ozawa

A Human Anti-M2 Antibody Mediates Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) and Cytokine Secretion by Resting and Cytokine-Preactivated Natural Killer (NK) Cells

scientific article published on 27 April 2015

A chimeric antigen receptor for TRAIL-receptor 1 induces apoptosis in various types of tumor cells

scientific article

A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days

scientific article published on 13 October 2013

A novel and simple method to produce large amounts of recombinant soluble peptide/major histocompatibility complex monomers for analysis of antigen-specific human T cell receptors

scientific article published on 19 November 2018

A novel rabbit immunospot array assay on a chip allows for the rapid generation of rabbit monoclonal antibodies with high affinity

scientific article

A novel, rapid and efficient method of cloning functional antigen-specific T-cell receptors from single human and mouse T-cells.

scientific article published on 4 May 2016

A rapid and efficient single-cell manipulation method for screening antigen-specific antibody-secreting cells from human peripheral blood.

scientific article published on 16 August 2009

Amplification and analysis of cDNA generated from a single cell by 5'-RACE: application to isolation of antibody heavy and light chain variable gene sequences from single B cells

scientific article published on 01 April 2006

Analysis of the clinical significance of DCLK1 colorectal cancer using novel monoclonal antibodies against DCLK1

scientific article published on 21 August 2018

Analysis of the epitope and neutralizing capacity of human monoclonal antibodies induced by hepatitis B vaccine.

scientific article published on 20 April 2010

Association Between High-Avidity T-Cell Receptors, Induced by α-Fetoprotein-Derived Peptides, and Anti-Tumor Effects in Patients With Hepatocellular Carcinoma.

scientific article published on 7 February 2017

Autoantibodies reactive to PEP08 are clinically related with morbidity and severity of interstitial lung disease in connective tissue diseases

scientific article published on 25 July 2018

Cell-microarray analysis of antigen-specific B-cells: single cell analysis of antigen receptor expression and specificity.

scientific article published in November 2007

Characterization of a fully human monoclonal antibody against extracellular domain of matrix protein 2 of influenza A virus.

scientific article

Cisplatin-induced non-canonical endocytosis of EGFR via p38 phosphorylation of the C-terminal region containing Ser-1015 in non-small cell lung cancer cells.

scientific article

Comprehensive analysis of the functional TCR repertoire at the single-cell level

scientific article published on 11 January 2008

Cutting Edge: B Cells Expressing Cyclic Citrullinated Peptide-Specific Antigen Receptor Are Tolerized in Normal Conditions

scientific article published on 12 November 2018

Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain.

scientific article published on 17 August 2016

Fully human monoclonal antibodies to TRAIL-R1 enhance TRAIL-induced apoptosis via activation of caspase-8 pathway

scientific article published on 18 May 2016

Generation of TRAIL-receptor 1-specific human monoclonal Ab by a combination of immunospot array assay on a chip and human Ab-producing mice.

scientific article published in December 2010

HELIOS-BCL11B fusion gene involvement in a t(2;14)(q34;q32) in an adult T-cell leukemia patient.

scientific article

Human monoclonal antibodies against West Nile virus from Japanese encephalitis-vaccinated volunteers

scientific article published on 14 April 2018

Identification of Novel Epitopes with Agonistic Activity for the Development of Tumor Immunotherapy Targeting TRAIL-R1.

scientific article

Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis.

scientific article published on 23 February 2018

Identification of an HLA class I allele closely involved in the autoantigen presentation in acquired aplastic anemia.

scientific article published on 23 February 2017

Identification of antigen-specific B cells by concurrent monitoring of intracellular Ca2+ mobilization and antigen binding with microwell array chip system equipped with a CCD imager

scientific article published in August 2009

Isolation of Antigen-Specific, Antibody-Secreting Cells Using a Chip-Based Immunospot Array

scientific article published on 01 January 2019

Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation

scientific article

MAC-CCD system: a novel lymphocyte microwell-array chip system equipped with CCD scanner to generate human monoclonal antibodies against influenza virus.

scientific article

Monoclonal antibody against citrullinated peptides obtained from rheumatoid arthritis patients reacts with numerous citrullinated microbial and food proteins.

scientific article published on May 2015

Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants

publication published on 01 January 2022

Physiological target, molecular evolution and pathogenic functions of a monoclonal ACPA obtained from an RA patient

scientific article published on 04 July 2020

Production of a rabbit monoclonal antibody for highly sensitive detection of citrus mosaic virus and related viruses

scientific article published on 15 April 2020

Production of monoclonal antibodies against GPCR using cell-free synthesized GPCR antigen and biotinylated liposome-based interaction assay.

scientific article published on 10 June 2015

Rapid isolation of antigen-specific antibody-secreting cells using a chip-based immunospot array

scientific article published on April 28, 2011

Rapid isolation of viral integration site reveals frequent integration of HTLV-1 into expressed loci

scientific article published on 26 February 2004

Reduced level of the BCL11B protein is associated with adult T-cell leukemia/lymphoma

scientific article

Relationship between T cell receptor clonotype and PD-1 expression of tumor-infiltrating lymphocytes in colorectal cancer

scientific article published on 22 May 2020

Retroviral vectors for homologous recombination provide efficient cloning and expression in mammalian cells.

scientific article published on 22 January 2014

SFMAC: a novel method for analyzing multiple parameters on lymphocytes with a single fluorophore in cell-microarray system

scientific article published in April 2009

Screening of antigen-specific antibody-secreting cells.

scientific article published on January 2012

Single lymphocyte analysis with a microwell array chip

scientific article

TRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo

scientific article published on 04 May 2016

The binding affinity of a soluble TCR-Fc fusion protein is significantly improved by crosslinkage with an anti-Cβ antibody

scientific article published on 01 May 2012

Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets

scientific article

Validation of cross-genotype neutralization by hepatitis B virus-specific monoclonal antibodies by in vitro and in vivo infection.

scientific article