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List of works by Martin Turner

A New Mechanism of Gene Regulation Mediated by Noncoding RNA

article

A RAC-GEF network critical for early intestinal tumourigenesis

scientific article published on 04 January 2021

A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas

scientific article published on 25 July 2004

A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

scientific journal article

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

scientific article (publication date: 16 September 2002)

A functional screen of RNA binding proteins identifies genes that promote or limit the accumulation of CD138+ plasma cells

scientific article published on 22 April 2022

A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival.

scientific article

Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.

scientific article

Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2

scientific article published on 01 June 2019

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress

scientific article published on 12 January 2016

Antigen phagocytosis by B cells is required for a potent humoral response

scientific article published on 09 July 2018

B-cell responses to B-cell activation factor of the TNF family (BAFF) are impaired in the absence of PI3K delta

scientific article published on 01 December 2008

BCR activation of PI3K is Vav-independent in murine B cells.

scientific article published in November 2004

CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav.

scientific article published in May 1998

Cell cycle RNA regulons coordinating early lymphocyte development.

scientific article published on 23 February 2017

Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals

scientific article

Characterization of ligand binding by the human p55 tumour-necrosis-factor receptor. Involvement of individual cysteine-rich repeats

scientific article published on 01 August 1994

Characterization of the B Cell Transcriptome Bound by RNA-Binding Proteins with iCLIP.

scientific article published on January 2017

Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

scientific article published on 06 April 2016

Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells.

scientific article

Defective immunoglobulin class switching in Vav-deficient mice is attributable to compromised T cell help

scientific article published on 01 February 1999

Deletion of AU-rich elements within the Bcl2 3'UTR reduces protein expression and B cell survival in vivo

scientific article

Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia

scientific article

Detection of protein-protein interactions by ribosome display and protein in situ immobilisation.

scientific article

Differential requirements of PI3K subunits for BCR or BCR/CD19-induced ERK activation

scientific article published on 01 January 2006

Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability.

scientific article published on 20 June 2012

Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms

scientific article

GIMAP1 Is Essential for the Survival of Naive and Activated B Cells In Vivo

scientific article published on 30 November 2015

Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils

scientific article published on 15 October 2006

Generation and characterisation of mice deficient in the multi-GTPase domain containing protein, GIMAP8

scientific journal article

Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation.

scientific article published on 4 May 2015

Granulocyte-macrophage colony stimulating factor induces both HLA-DR expression and cytokine production by human monocytes.

scientific article published on January 1990

Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster

scientific article

Immunological function in mice lacking the Rac-related GTPase RhoG

scientific article

Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

scientific article (publication date: 19 June 2014)

Interleukin 7 and interleukin 4 stimulate human thymocyte growth through distinct mechanisms

scientific article published on 01 January 1990

Intrathyroidal cytokine production in thyroid disease

scientific article published on 01 June 1989

Is transcription the dominant force during dynamic changes in gene expression?

scientific article published on January 2011

Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1.

scientific article published on 10 April 2017

Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue.

scientific article published on 29 January 2004

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression

scientific article published on 28 March 2019

MicroRNA 125b inhibition of B cell differentiation in germinal centers

scientific article

MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis.

scientific article published on 14 December 2015

MicroRNA-155 is essential for the optimal proliferation and survival of plasmablast B cells

scientific article published on 16 May 2019

Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion

scientific article published on 30 October 2019

Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases

scientific article published on 11 February 2002

Noncoding RNA and its associated proteins as regulatory elements of the immune system.

scientific article published on June 2014

PI3K Signaling in B Cell and T Cell Biology.

scientific article published on 3 November 2014

PLCgamma2 regulates Bcl-2 levels and is required for survival rather than differentiation of marginal zone and follicular B cells

scientific article published on 01 August 2004

Pharmacological inhibition of glycogen synthase kinase 3 regulates T cell development in vitro

scientific article

Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes.

scientific article

Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction

scientific article

Polypyrimidine tract-binding proteins are essential for B cell development

scientific article published on 21 February 2020

Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma.

scientific article published on 18 May 2012

Putative GTPase GIMAP1 is critical for the development of mature B and T lymphocytes

scientific journal article

RNA Binding Proteins As Regulators of Oxidative Stress Identified by a Targeted CRISPR-Cas9 Single Guide RNA Library

scientific article published on 04 June 2021

RNA binding proteins as regulators of immune cell biology.

scientific article published on 21 July 2015

RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism.

scientific article published on 11 September 2017

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence

scientific journal article

RNA-binding proteins control gene expression and cell fate in the immune system.

scientific article published on 18 January 2018

RNA-binding proteins in hematopoiesis and hematological malignancy

scientific article published on 09 April 2019

RNA-binding proteins mind the GAPs.

scientific article published in January 2017

Rac GTPases play critical roles in early T-cell development

scientific article published on 16 December 2008

Regulation of B- and T-cell differentiation by a single microRNA

scientific article published on 01 June 2008

Regulation of B-cell differentiation by microRNAs and RNA-binding proteins.

scientific article published on December 2008

Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK

scientific article published on 01 June 2003

Regulation of lymphocyte development and function by RNA-binding proteins.

scientific article published on 10 February 2012

Requirement of bic/microRNA-155 for normal immune function

scientific article

RhoG regulates gene expression and the actin cytoskeleton in lymphocytes

scientific article

Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets

scientific article published on May 2005

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

scientific article

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

scientific article published on 01 June 2001

Signalling circuits that direct early B-cell development

scientific article published on 06 March 2019

Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection ⬇️

scientific article published on 09 September 2010

Structural organization of the mouse phosphatidylinositol 3-kinase p110d gene.

scientific article

Syk and Fyn Are Required by Mouse Megakaryocytes for the Rise in Intracellular Calcium Induced by a Collagen-related Peptide

scientific article published on 01 October 1997

Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development.

scientific article published in September 2006

Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool

scientific article

Synergistic activation of PKD by the B cell antigen receptor and CD19 requires PI3K, Vav1 and PLCgamma

scientific article published on 27 December 2005

T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis

scientific article

The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response

scientific article published on 5 February 2007

The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck)

scientific article published on 01 August 1999

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

scientific journal article

The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic β-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression

scientific article published on 26 August 2016

The RNA-binding protein HuR is essential for the B cell antibody response.

scientific article published on 23 February 2015

The RNA-binding protein HuR is required for maintenance of the germinal centre response

scientific article published on 12 November 2021

The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers

scientific article

The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation

scientific article published on 24 May 2016

The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis

scientific article published on 07 December 2018

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

scientific article

The Role of p110δ in the Development and Activation of B Lymphocytes.

scientific article published on January 2015

The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation

scientific article

The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.

scientific article

The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion

article

The p110delta subunit of phosphoinositide 3-kinase is required for the lipopolysaccharide response of mouse B cells.

scientific article published in November 2004

The role of endothelial PI3Kgamma activity in neutrophil trafficking

scientific article

The tyrosine kinase Lyn is required for B cell development beyond the T1 stage in the spleen: rescue by over-expression of Bcl-2.

scientific article published in April 2002

The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells.

scientific article published in April 2004

Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4.

scientific article

Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells.

scientific article published on 13 September 2017

Transcriptome Analysis of Infected and Bystander Type 2 Alveolar Epithelial Cells during Influenza A Virus Infection Reveals Wnt Pathway Downregulation

scientific article published on 12 October 2018

Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells

scientific article published on 09 July 2018

Tribbles-2 is a novel regulator of inflammatory activation of monocytes

scientific article published on 24 October 2008

Tyrosine kinase SYK: essential functions for immunoreceptor signalling

scientific article (publication date: March 2000)

Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets

scientific article (publication date: 26 February 1999)

Uncovering the Role of RNA-Binding Proteins in Gene Expression in the Immune System.

scientific article published on 23 May 2018

Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation.

scientific article

Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3.

scientific article published on February 2007

Vav is required for cyclin D2 induction and proliferation of mouse B lymphocytes activated via the antigen Receptor.

scientific article

Vav proteins are required for B-lymphocyte responses to LPS

scientific article published on 05 April 2005

Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization

scientific article published on 31 August 2005

Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.

scientific article

Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.

scientific article published in November 2002

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