List of works - Philippe Benaroch

A multi-Fc-species system for recombinant antibody production

scientific article

AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis

scientific article

AP2 clathrin adaptor complex, but not AP1, controls the access of the major histocompatibility complex (MHC) class II to endosomes.

scientific article published on 4 March 2005

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

scientific article

Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes.

scientific article

Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone.

scientific article published on April 2003

Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.

scientific article

Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.

scientific article published on October 1999

CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells.

scientific article

Cellular induction of chronic allotype suppression of IgG2a in Ighb/b homozygous mice and its abrogation by in vivo treatment with anti-CD8 monoclonal antibody

scientific article

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling

scientific article

Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

scientific article published on 07 November 2019

Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors

scientific article published on 07 October 2019

Critical role for the kinesin KIF3A in the HIV life cycle in primary human macrophages

scientific article

Developmental regulation of MHC II expression and transport in human plasmacytoid-derived dendritic cells.

scientific article published on 17 November 2008

Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.

scientific article published on October 2003

Dynamics of HIV-containing compartments in macrophages reveal sequestration of virions and transient surface connections

scientific article (publication date: 2013)

Effects of HIV-1 Nef on retrograde transport from the plasma membrane to the endoplasmic reticulum.

scientific article

Enhancement in Igha mouse strains of the "natural" suppressive activity of normal T splenocytes against the expression of Igh-1b allotype. I. Molecular aspects of the chronic suppression obtained

scientific article published on 01 January 1988

Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells

scientific article published on July 2002

Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages

scientific article published on 8 June 2015

Fully in vitro selection of recombinant antibodies

scientific article

HIV trafficking in host cells: motors wanted!

scientific article published on 10 October 2013

HIV-1 Buds and Accumulates in “Nonacidic” Endosomes of Macrophages

article

HIV-1 Nef impairs MHC class II antigen presentation and surface expression

scientific article

HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.

scientific article

HIV-1 assembly in macrophages

scientific article published on 07 April 2010

HIV-mediated up-regulation of invariant chain (CD74) correlates with generalized immune activation in HIV+ subjects

scientific article

How MHC class II molecules reach the endocytic pathway

scientific article published on January 1995

Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain.

scientific article

Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

scientific article

Human macrophages accumulate HIV-1 particles in MHC II compartments

scientific article (publication date: October 2002)

Identification of T cell peptides from C gamma 2ab involved in IgG2ab T cell-induced allotypic suppression. Relationship with the MHC haplotype of the suppressor T cell-donor Igha mice.

scientific article published in August 1993

Induction of immunoglobulin allotypic suppression in the rabbit: a cellular approach.

scientific article

Interaction of MHC class II molecules with the invariant chain: role of the invariant chain (81-90) region

scientific article

Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis.

scientific article published on 02 January 2014

MHC class II dimer of dimers

scientific article published in Nature

Macrophages hide HIV in the urethra

scientific article published on 01 April 2019

Mapping functional regions in the lumenal domain of the class II-associated invariant chain

scientific article

Mapping the human DC lineage through the integration of high-dimensional techniques.

scientific article published on 4 May 2017

Multiple roles of the invariant chain in MHC class II function

scientific journal article

Myeloid Cell Interaction with HIV: A Complex Relationship.

scientific article published on 30 November 2017

Nef variants from non-pathogenic lentiviral strains inhibit iron uptake through an AP2-dependent inhibition of transferrin endocytosis.

scientific article published on 19 September 2013

Normal T splenocytes are able to induce immunoglobulin allotypic suppression in F1 hybrid mice

scientific article published on 01 February 1987

Plasmodium chabaudi and Trypanosoma cruzi infections can reverse IgG2ab chronic suppression in mice

scientific article

Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments

scientific article published on February 2007

Protein interaction mapping: a Drosophila case study

scientific article

Rab27a and Rab27b control different steps of the exosome secretion pathway

scientific article

Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate

scientific article

Role of CD4+ and CD8+ cell subsets during amplification of natural T cell activity against IgG2ab in Igha mice and during induction of IgG2ab allotype suppression in Igha/b mice

scientific article published on 01 August 1993

Role of Gag and lipids during HIV-1 assembly in CD4(+) T cells and macrophages.

scientific article published on 25 June 2014

Sensing of HIV-1 Entry Triggers a Type I Interferon Response in Human Primary Macrophages.

scientific article published on 10 May 2017

Single Nef proteins from HIV type 1 subtypes C and F fail to upregulate invariant chain cell surface expression but are active for other functions.

scientific article

T cell-induced Ig allotypic suppression in mice. Basis for emergence or tolerization, during the perinatal period, of natural T cells specific to the IgG2ab allotype

scientific article published on 01 April 1994

T cell-induced Ig allotypic suppression in mice. II. Both CD4+ CD8- and CD4- CD8+ T cell subsets from sensitized Igha mice are required to induce suppression of Igh-1b allotype expression

scientific article published on 01 January 1989

T cell-induced allotypic suppression. Origin of the CD8+ T cells maintaining IgG2ab suppression

scientific article published in September 1992

T cell-induced suppression of IgG2ab expression in vivo leads to a large reduction of C gamma 2ab mRNA levels

scientific article published on 01 February 1993

T-cell-induced chronic immunoglobulin allotypic suppression in mouse

scientific article

TLR3 Activation of Intratumoral CD103 Dendritic Cells Modifies the Tumor Infiltrate Conferring Anti-tumor Immunity

scientific article published on 20 March 2019

TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking

scientific article

Tetramer data reinterpreted

scientific article published in Nature

Tetrameric cell-surface MHC class I molecules.

scientific article

Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex.

scientific article published in November 2000

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal

scientific article published on 06 March 2018

List of works by Philippe Benaroch

A multi-Fc-species system for recombinant antibody production

AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis

AP2 clathrin adaptor complex, but not AP1, controls the access of the major histocompatibility complex (MHC) class II to endosomes.

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes.

Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone.

Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.

Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.

CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells.

Cellular induction of chronic allotype suppression of IgG2a in Ighb/b homozygous mice and its abrogation by in vivo treatment with anti-CD8 monoclonal antibody

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling

Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors

Critical role for the kinesin KIF3A in the HIV life cycle in primary human macrophages

Developmental regulation of MHC II expression and transport in human plasmacytoid-derived dendritic cells.

Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.

Dynamics of HIV-containing compartments in macrophages reveal sequestration of virions and transient surface connections

Effects of HIV-1 Nef on retrograde transport from the plasma membrane to the endoplasmic reticulum.

Enhancement in Igha mouse strains of the "natural" suppressive activity of normal T splenocytes against the expression of Igh-1b allotype. I. Molecular aspects of the chronic suppression obtained

Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells

Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages

Fully in vitro selection of recombinant antibodies

HIV trafficking in host cells: motors wanted!

HIV-1 Buds and Accumulates in “Nonacidic” Endosomes of Macrophages

HIV-1 Nef impairs MHC class II antigen presentation and surface expression

HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.

HIV-1 assembly in macrophages

HIV-mediated up-regulation of invariant chain (CD74) correlates with generalized immune activation in HIV+ subjects

How MHC class II molecules reach the endocytic pathway

Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain.

Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

Human macrophages accumulate HIV-1 particles in MHC II compartments

Identification of T cell peptides from C gamma 2ab involved in IgG2ab T cell-induced allotypic suppression. Relationship with the MHC haplotype of the suppressor T cell-donor Igha mice.

Induction of immunoglobulin allotypic suppression in the rabbit: a cellular approach.

Interaction of MHC class II molecules with the invariant chain: role of the invariant chain (81-90) region

Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis.

MHC class II dimer of dimers

Macrophages hide HIV in the urethra

Mapping functional regions in the lumenal domain of the class II-associated invariant chain

Mapping the human DC lineage through the integration of high-dimensional techniques.

Multiple roles of the invariant chain in MHC class II function

Myeloid Cell Interaction with HIV: A Complex Relationship.

Nef variants from non-pathogenic lentiviral strains inhibit iron uptake through an AP2-dependent inhibition of transferrin endocytosis.

Normal T splenocytes are able to induce immunoglobulin allotypic suppression in F1 hybrid mice

Plasmodium chabaudi and Trypanosoma cruzi infections can reverse IgG2ab chronic suppression in mice

Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments

Protein interaction mapping: a Drosophila case study

Rab27a and Rab27b control different steps of the exosome secretion pathway

Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate

Role of CD4+ and CD8+ cell subsets during amplification of natural T cell activity against IgG2ab in Igha mice and during induction of IgG2ab allotype suppression in Igha/b mice

Role of Gag and lipids during HIV-1 assembly in CD4(+) T cells and macrophages.

Sensing of HIV-1 Entry Triggers a Type I Interferon Response in Human Primary Macrophages.

Single Nef proteins from HIV type 1 subtypes C and F fail to upregulate invariant chain cell surface expression but are active for other functions.

T cell-induced Ig allotypic suppression in mice. Basis for emergence or tolerization, during the perinatal period, of natural T cells specific to the IgG2ab allotype

T cell-induced Ig allotypic suppression in mice. II. Both CD4+ CD8- and CD4- CD8+ T cell subsets from sensitized Igha mice are required to induce suppression of Igh-1b allotype expression

T cell-induced allotypic suppression. Origin of the CD8+ T cells maintaining IgG2ab suppression

T cell-induced suppression of IgG2ab expression in vivo leads to a large reduction of C gamma 2ab mRNA levels

T-cell-induced chronic immunoglobulin allotypic suppression in mouse

TLR3 Activation of Intratumoral CD103 Dendritic Cells Modifies the Tumor Infiltrate Conferring Anti-tumor Immunity

TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking

Tetramer data reinterpreted

Tetrameric cell-surface MHC class I molecules.

Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex.

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal