List of works - Michael Nonnemacher

AP-1-directed human T cell leukemia virus type 1 viral gene expression during monocytic differentiation

scientific article published on 7 July 2006

Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier.

scientific article

Broad-Spectrum and Personalized Guide RNAs for CRISPR/Cas9 HIV-1 Therapeutics

scientific article published on 27 August 2018

CCAAT/enhancer-binding proteins and the pathogenesis of retrovirus infection

scientific article published on April 2009

CCAAT/enhancer-binding proteins modulate human T cell leukemia virus type 1 long terminal repeat activation

scientific article

Cellular phenotype impacts human immunodeficiency virus type 1 viral protein R subcellular localization

scientific article

Co-culture model consisting of human brain microvascular endothelial and peripheral blood mononuclear cells.

scientific article published on 20 May 2016

Cocaine alters cytokine profiles in HIV-1-infected African American individuals in the DrexelMed HIV/AIDS genetic analysis cohort

scientific article

Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences

scientific article

Defining the molecular mechanisms of HIV-1 Tat secretion: PtdIns(4,5)P2 at the epicenter.

scientific article

Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic development

scientific article published on 14 March 2012

Designing broad-spectrum anti-HIV-1 gRNAs to target patient-derived variants.

scientific article published on 31 October 2017

Development of Land Use Regression models for PM(2.5), PM(2.5) absorbance, PM(10) and PM(coarse) in 20 European study areas; results of the ESCAPE project

scientific article published in October 2012

Development of NO2 and NOx land use regression models for estimating air pollution exposure in 36 study areas in Europe – The ESCAPE project

scholarly article by Rob Beelen et al published June 2013 in Atmospheric Environment

Effect of μ-opioid agonist DAMGO on surface CXCR4 and HIV-1 replication in TF-1 human bone marrow progenitor cells.

scientific article

Epigenetics, drugs of abuse, and the retroviral promoter.

scientific article

Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences

scientific article

Extracellular HIV-1 viral protein R affects astrocytic glyceraldehyde 3-phosphate dehydrogenase activity and neuronal survival.

scientific article published on June 2013

Extracellular human immunodeficiency virus type 1 viral protein R causes reductions in astrocytic ATP and glutathione levels compromising the antioxidant reservoir ⬇️

scientific article published on June 9, 2012

Functional Studies of CCAAT/Enhancer Binding Protein Site Located Downstream of the Transcriptional Start Site.

scientific article published on 15 November 2017

Functional impact of HIV-1 Tat on cells of the CNS and its role in HAND

scientific article published on 23 June 2020

Genetic variation and HIV-associated neurologic disease.

scientific article

Genetic variation and function of the HIV-1 Tat protein

scientific article published on 05 March 2019

HIV-1 Latency and Eradication: Past, Present and Future

scientific article published on 24 March 2016

HIV-1 Vpr binding to HIV-1 LTR C/EBP cis-acting elements and adjacent regions is sequence-specific.

scientific article

High-affinity interaction between HIV-1 Vpr and specific sequences that span the C/EBP and adjacent NF-kappaB sites within the HIV-1 LTR correlate with HIV-1-associated dementia.

scientific article

Human Immunodeficiency Virus Viral Protein R as an Extracellular Protein in Neuropathogenesis ⬇️

scientific article published on January 1, 2011

Identification of binding sites for members of the CCAAT/enhancer binding protein transcription factor family in the simian immunodeficiency virus long terminal repeat

scientific article published in January 2003

Impact of Tat Genetic Variation on HIV-1 Disease

scientific article

Impact of age on markers of HIV-1 disease

scientific article published on January 2013

Impact of viral activators and epigenetic regulators on HIV-1 LTRs containing naturally occurring single nucleotide polymorphisms.

scientific article published on 5 January 2015

Innate and adaptive factors regulating human immunodeficiency virus type 1 genomic activation.

scientific article

Interaction between CCAAT/enhancer binding protein and cyclic AMP response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage.

scientific article published on February 2001

Interaction between Tat and Drugs of Abuse during HIV-1 Infection and Central Nervous System Disease

scientific article

Molecular characterization and functional analysis of a secA gene homolog in Actinobacillus actinomycetemcomitans

scientific article published on 01 January 2000

Molecular evidence for Acanthocephala as a subtaxon of Rotifera.

scientific article published on September 1996

PMA-induced differentiation of a bone marrow progenitor cell line activates HIV-1 LTR-driven transcription.

scientific article published on June 2007

Prediction of Human Immunodeficiency Virus Type 1 Subtype-Specific Off-Target Effects Arising from CRISPR-Cas9 Gene Editing Therapy

scientific article published on 01 August 2018

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain Barrier

scientific article published on 09 June 2016

Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage

scientific article

Regulation of human T-cell leukemia virus type 1 gene expression by Sp1 and Sp3 interaction with TRE-1 repeat III.

scientific article published on May 2006

Role of mu-opioids as cofactors in human immunodeficiency virus type 1 disease progression and neuropathogenesis ⬇️

scientific article published on 07 July 2011

Specific sequence configurations of HIV-1 LTR G/C box array result in altered recruitment of Sp isoforms and correlate with disease progression.

scientific article

Structural and functional studies of CCAAT/enhancer binding sites within the human immunodeficiency virus type 1 subtype C LTR.

scientific article

Transcriptional regulation of the chemokine co-receptor CCR5 by the cAMP/PKA/CREB pathway.

scientific article

Variation of NO2 and NOx concentrations between and within 36 European study areas: Results from the ESCAPE study

scientific article published in December 2012

cAMP Signaling Enhances HIV-1 Long Terminal Repeat (LTR)-directed Transcription and Viral Replication in Bone Marrow Progenitor Cells

scientific article

List of works by Michael Nonnemacher

AP-1-directed human T cell leukemia virus type 1 viral gene expression during monocytic differentiation

Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier.

Broad-Spectrum and Personalized Guide RNAs for CRISPR/Cas9 HIV-1 Therapeutics

CCAAT/enhancer-binding proteins and the pathogenesis of retrovirus infection

CCAAT/enhancer-binding proteins modulate human T cell leukemia virus type 1 long terminal repeat activation

Cellular phenotype impacts human immunodeficiency virus type 1 viral protein R subcellular localization

Co-culture model consisting of human brain microvascular endothelial and peripheral blood mononuclear cells.

Cocaine alters cytokine profiles in HIV-1-infected African American individuals in the DrexelMed HIV/AIDS genetic analysis cohort

Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences

Defining the molecular mechanisms of HIV-1 Tat secretion: PtdIns(4,5)P2 at the epicenter.

Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic development

Designing broad-spectrum anti-HIV-1 gRNAs to target patient-derived variants.

Development of Land Use Regression models for PM(2.5), PM(2.5) absorbance, PM(10) and PM(coarse) in 20 European study areas; results of the ESCAPE project

Development of NO2 and NOx land use regression models for estimating air pollution exposure in 36 study areas in Europe – The ESCAPE project

Effect of μ-opioid agonist DAMGO on surface CXCR4 and HIV-1 replication in TF-1 human bone marrow progenitor cells.

Epigenetics, drugs of abuse, and the retroviral promoter.

Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences

Extracellular HIV-1 viral protein R affects astrocytic glyceraldehyde 3-phosphate dehydrogenase activity and neuronal survival.

Extracellular human immunodeficiency virus type 1 viral protein R causes reductions in astrocytic ATP and glutathione levels compromising the antioxidant reservoir ⬇️

Functional Studies of CCAAT/Enhancer Binding Protein Site Located Downstream of the Transcriptional Start Site.

Functional impact of HIV-1 Tat on cells of the CNS and its role in HAND

Genetic variation and HIV-associated neurologic disease.

Genetic variation and function of the HIV-1 Tat protein

HIV-1 Latency and Eradication: Past, Present and Future

HIV-1 Vpr binding to HIV-1 LTR C/EBP cis-acting elements and adjacent regions is sequence-specific.

High-affinity interaction between HIV-1 Vpr and specific sequences that span the C/EBP and adjacent NF-kappaB sites within the HIV-1 LTR correlate with HIV-1-associated dementia.

Human Immunodeficiency Virus Viral Protein R as an Extracellular Protein in Neuropathogenesis ⬇️

Identification of binding sites for members of the CCAAT/enhancer binding protein transcription factor family in the simian immunodeficiency virus long terminal repeat

Impact of Tat Genetic Variation on HIV-1 Disease

Impact of age on markers of HIV-1 disease

Impact of viral activators and epigenetic regulators on HIV-1 LTRs containing naturally occurring single nucleotide polymorphisms.

Innate and adaptive factors regulating human immunodeficiency virus type 1 genomic activation.

Interaction between CCAAT/enhancer binding protein and cyclic AMP response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage.

Interaction between Tat and Drugs of Abuse during HIV-1 Infection and Central Nervous System Disease

Molecular characterization and functional analysis of a secA gene homolog in Actinobacillus actinomycetemcomitans

Molecular evidence for Acanthocephala as a subtaxon of Rotifera.

PMA-induced differentiation of a bone marrow progenitor cell line activates HIV-1 LTR-driven transcription.

Prediction of Human Immunodeficiency Virus Type 1 Subtype-Specific Off-Target Effects Arising from CRISPR-Cas9 Gene Editing Therapy

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain Barrier

Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage

Regulation of human T-cell leukemia virus type 1 gene expression by Sp1 and Sp3 interaction with TRE-1 repeat III.

Role of mu-opioids as cofactors in human immunodeficiency virus type 1 disease progression and neuropathogenesis ⬇️

Specific sequence configurations of HIV-1 LTR G/C box array result in altered recruitment of Sp isoforms and correlate with disease progression.

Structural and functional studies of CCAAT/enhancer binding sites within the human immunodeficiency virus type 1 subtype C LTR.

Transcriptional regulation of the chemokine co-receptor CCR5 by the cAMP/PKA/CREB pathway.

Variation of NO2 and NOx concentrations between and within 36 European study areas: Results from the ESCAPE study

cAMP Signaling Enhances HIV-1 Long Terminal Repeat (LTR)-directed Transcription and Viral Replication in Bone Marrow Progenitor Cells