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List of works by Roberto S. Accolla

A family of trans-acting factors with distinct regulatory functions control expression of MHC class II genes.

scientific article

Active suppression of major histocompatibility complex class II gene expression during differentiation from B cells to plasma cells.

scientific article

Adequate antigen availability: a key issue for novel approaches to tumor vaccination and tumor immunotherapy.

scientific article published on 07 December 2012

Analysis of the antigen specific T cell repertoires in HIV infection

scientific article published in November 2001

Antibody-mediated activation of a deletion-mutant beta-galactosidase defective in the alpha region

scientific article published on 01 September 1976

Binding of one monoclonal antibody to human Ia molecules can be enhanced by a second monoclonal antibody

scientific article published on 01 September 1981

Biochemical aspects of human Ia molecules

scientific article published on 01 September 1983

Block of Stat-1 activation in macrophages phagocytosing bacteria causes reduced transcription of CIITA and consequent impaired antigen presentation.

scientific article

Boosting the MHC Class II-Restricted Tumor Antigen Presentation to CD4+ T Helper Cells: A Critical Issue for Triggering Protective Immunity and Re-Orienting the Tumor Microenvironment Toward an Anti-Tumor State

scientific article published on 18 February 2014

CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection, and specific antitumor memory.

scientific article published on June 2006

CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches

scientific article published on 26 November 2018

CIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens

scientific article published on 22 September 2020

Class II transactivator-induced MHC class II expression in pancreatic cancer cells leads to tumor rejection and a specific antitumor memory response.

scientific article

Constitutive expression of CD69 in interspecies T-cell hybrids and locus assignment to human chromosome 12.

scientific article

Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response

scientific article

Detection of human chromosomes in somatic cell hybrids by PCR analysis

scientific article published on 01 January 1993

Different staphylococcal enterotoxins bind preferentially to distinct major histocompatibility complex class II isotypes

scientific article published on 01 November 1989

Distinct HLA-DR epitopes and distinct families of HLA-DR molecules defined by 15 monoclonal antibodies (mAb) either anti-DR or allo-anti-Iak crossreacting with human DR molecule. I. Cross-inhibition studies of mAb cell surface fixation and differenti

scientific article published on 01 February 1983

Divergent evolution in the mechanisms controlling major histocompatibility complex class II gene transcription in mouse and human.

scientific article

Down syndrome, autoimmunity and T regulatory cells

scientific article published on 01 September 2012

Evidence for a trans-acting activator function regulating the expression of the human CD5 antigen.

scientific article published on January 1994

Heterogeneity of lymphokine-activated killer (LAK) populations at the clonal level: both NK and CD3+, CD4-, CD8- clones efficiently mediate tumor cell killing.

scientific article published in October 1988

Human naive CD4 T-cell clones specific for HIV envelope persist for years in vivo in the absence of antigenic challenge

scientific article published on October 2005

Ia-negative B-cell variants reveal a coordinate regulation in the transcription of the HLA class II gene family

scientific article published on 01 January 1984

In vivo modification of major histocompatibility complex class II DRA promoter occupancy mediated by the AIR-1 trans-activator.

scientific article published on October 1994

Inhibition of human T cell leukemia virus type 2 replication by the suppressive action of class II transactivator and nuclear factor Y.

scholarly article

Investigating human T cell lymphotropic retrovirus (HTLV) Tax function with molecular and immunophenotypic techniques

scientific article published on January 2014

Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL

scientific article published on 4 July 2015

MHC immunoevasins: protecting the pathogen reservoir in infection.

scientific article

Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 Tax-1 function and inhibits viral replication.

scientific article

Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication

scientific article published on 7 July 2011

Molecular genotyping of the HLA-DQ ? gene region

article

Monoclonal antibodies against carcinoembryonic antigen (CEA) used in a solid-phase enzyme immunoassay. First clinical results

scientific article published on 01 March 1982

New Strategies of Mammary Cancer Vaccination ⬇️

scientific article published on September 1, 2010

Nonantigen specific CD8+ T suppressor lymphocytes originate from CD8+CD28- T cells and inhibit both T-cell proliferation and CTL function.

scientific article published in February 2004

Optimal MHC-II-restricted tumor antigen presentation to CD4+ T helper cells: the key issue for development of anti-tumor vaccines ⬇️

scientific article

Physiologic target of the Air-1 trans-activator revealed by stable transfection assay.

scientific article published on January 1994

Preservation of clonal heterogeneity of the Pneumocystis carinii-specific CD4 T cell repertoire in HIV infected, asymptomatic individuals

scientific article

Restriction factors in human retrovirus infections and the unprecedented case of CIITA as link of intrinsic and adaptive immunity against HTLV-1

scientific article published on 29 November 2019

Sandwich enzyme immunoassay using three monoclonal antibodies against different epitopes of carcinoembryonic antigen (CEA)

scientific article published on 01 August 1982

Structural analysis of the CD69 early activation antigen by two monoclonal antibodies directed to different epitopes

scientific article published on 01 January 1991

Subsets of human Ia-like molecules defined by monoclonal antibodies

scientific article published on 01 May 1981

Targeted delivery of tumor necrosis factor-alpha to tumor vessels induces a therapeutic T cell-mediated immune response that protects the host against syngeneic tumors of different histologic origin

scientific article published on April 2006

The HLA class II transcriptional activator blocks the function of HIV-1 Tat and inhibits viral replication

scientific article published on 01 October 2002

The MHC class II transactivator (CIITA) mRNA stability is critical for the HLA class II gene expression in myelomonocytic cells.

scientific article published in February 2005

The MHC class II transcriptional activator (CIITA) inhibits HTLV-2 viral replication by blocking the function of the viral transactivator Tax-2.

scientific article published on 2 October 2003

The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators

scientific article published on 22 August 2013

The complex interplay of the DQB1 and DQA1 loci in the generation of the susceptible and protective phenotype for insulin-dependent diabetes mellitus.

scientific article published in April 1994

The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse.

scientific article

The importance of cross-reactions between species: mouse allo-anti-Ia monoclonal antibodies as a powerful tool to define human Ia subsets

scientific article published on 01 September 1983

The molecular biology of MHC genes

scientific article published on 01 April 1991

Therapy-induced antitumor vaccination by targeting tumor necrosis factor alpha to tumor vessels in combination with melphalan

scientific article published in December 2007

Transcriptional regulation of MHC class II genes ⬇️

scientific article published on January 1, 1995

Tumor rejection by gene transfer of the MHC class II transactivator in murine mammary adenocarcinoma cells.

scientific article published on May 2003

Typing of a polymorphic human gene conferring susceptibility to insulin-dependent diabetes mellitus by picosecond-resolved FRET on non-purified/non-amplified genomic DNA.

scientific article

Unsung Hero Robert C. Gallo

scientific article

Use of radiolabelled monoclonal anti-CEA antibodies for the detection of human carcinomas by external photoscanning and tomoscintigraphy

scientific article published on 01 December 1981

ras-family gene mutations in neoplasia of the ampulla of vater

article

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