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List of works by Timothy L. Yahr

A critical new pathway for toxin secretion?

scientific article published on 01 September 2006

A novel anti-anti-activator mechanism regulates expression of the Pseudomonas aeruginosa type III secretion system

scientific journal article

Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling.

scientific article published on 3 September 2010

Biochemical characterization of a regulatory cascade controlling transcription of the Pseudomonas aeruginosa type III secretion system

scientific article published on 29 December 2006

Biochemical relationships between the 53-kilodalton (Exo53) and 49-kilodalton (ExoS) forms of exoenzyme S of Pseudomonas aeruginosa.

scientific article published on March 1997

Characterization of ExsA and of ExsA-dependent promoters required for expression of the Pseudomonas aeruginosa type III secretion system.

scientific article

Characterization of ExsC and ExsD self-association and heterocomplex formation.

scientific article

Chronic Pseudomonas aeruginosa infection reduces surfactant levels by inhibiting its biosynthesis.

scientific article published on 12 December 2006

Control of gene expression by type III secretory activity.

scientific article published on 8 April 2008

Exotoxin S secreted by internalized Pseudomonas aeruginosa delays lytic host cell death

scientific article published on 07 February 2022

ExsA and LcrF recognize similar consensus binding sites, but differences in their oligomeric state influence interactions with promoter DNA

scientific journal article

ExsA recruits RNA polymerase to an extended -10 promoter by contacting region 4.2 of sigma-70

scientific article

ExsD inhibits expression of the Pseudomonas aeruginosa type III secretion system by disrupting ExsA self-association and DNA binding activity

scientific journal article

ExsD is a negative regulator of the Pseudomonas aeruginosa type III secretion regulon

scientific journal article

Functional analyses of the RsmY and RsmZ small non-coding regulatory RNAs in Pseudomonas aeruginosa

scientific article published on 20 February 2018

Functional domains of ExsA, the transcriptional activator of the Pseudomonas aeruginosa type III secretion system

scientific article

Genetic relationship between the 53- and 49-kilodalton forms of exoenzyme S from Pseudomonas aeruginosa.

scientific article published on March 1996

Genome Sequences of Two Pseudomonas aeruginosa Isolates with Defects in Type III Secretion System Gene Expression from a Chronic Ankle Wound Infection

publication published on 14 July 2021

Glucose depletion in the airway surface liquid is essential for sterility of the airways

scientific article (publication date: 2011)

Hfq and sRNA 179 Inhibit Expression of the Pseudomonas aeruginosa cAMP-Vfr and Type III Secretion Regulons

scientific article published on 16 June 2020

Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon ⬇️

scientific article published on November 1, 1997

In vitro and in vivo characterization of the Pseudomonas aeruginosa cyclic AMP (cAMP) phosphodiesterase CpdA, required for cAMP homeostasis and virulence factor regulation.

scientific article

Inhibition of Pseudomonas aeruginosa ExsA DNA-Binding Activity by N-Hydroxybenzimidazoles

scientific article published on 16 November 2015

Inhibition of the Injectisome and Flagellar Type III Secretion Systems by INP1855 Impairs Pseudomonas aeruginosa Pathogenicity and Inflammasome Activation

scientific article published on 13 July 2016

Limiting too much of a good thing: a negative feedback mechanism prevents unregulated translocation of type III effector proteins.

scientific article published on 14 December 2007

Orientation of Pseudomonas aeruginosa ExsA Monomers Bound to Promoter DNA and Base-Specific Contacts with the PexoT Promoter ⬇️

scientific article published on March 9, 2012

Post-transcriptional regulation of type III secretion in plant and animal pathogens.

scientific article published on 9 February 2017

Pseudomonas aeruginosa Can Diversify after Host Cell Invasion to Establish Multiple Intracellular Niches

scientific article published in 2022

Pseudomonas aeruginosa utilizes the type III secreted toxin ExoS to avoid acidified compartments within epithelial cells

scientific article

Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs

scientific article

Secretion of Flagellar Proteins by the Pseudomonas aeruginosa Type III Secretion-Injectisome System

scientific article published on 6 April 2015

Self-association is required for occupation of adjacent binding sites in Pseudomonas aeruginosa type III secretion system promoters.

scientific article

Self‐trimerization of ExsD limits inhibition of the Pseudomonas aeruginosa transcriptional activator ExsA in vitro ⬇️

scientific article published on January 24, 2013

The AlgZR two-component system recalibrates the RsmAYZ posttranscriptional regulatory system to inhibit expression of the Pseudomonas aeruginosa type III secretion system.

scientific article

The Impact of ExoS on Pseudomonas aeruginosa Internalization by Epithelial Cells Is Independent of fleQ and Correlates with Bistability of Type Three Secretion System Gene Expression.

scientific article published in May 2018

The Pseudomonas aeruginosa Magnesium Transporter MgtE Inhibits Type III Secretion System Gene Expression by Stimulating rsmYZ Transcription.

scientific article published on 28 August 2017

The Pseudomonas aeruginosa Vfr regulator controls global virulence factor expression through cyclic AMP-dependent and -independent mechanisms

scientific article

The RNA Helicase DeaD Stimulates ExsA Translation To Promote Expression of the Pseudomonas aeruginosa Type III Secretion System.

scientific article published on 8 June 2015

The distal ExsA-binding site in Pseudomonas aeruginosa type III secretion system promoters is the primary determinant for promoter-specific properties

scientific article

The genetic basis for the commitment to chronic versus acute infection in Pseudomonas aeruginosa.

scientific article

The transiently ordered regions in intrinsically disordered ExsE are correlated with structural elements involved in chaperone binding.

scientific article published on 25 November 2011

Transcriptional regulation of the Pseudomonas aeruginosa type III secretion system.

scientific article

Translocation of ExsE into Chinese hamster ovary cells is required for transcriptional induction of the Pseudomonas aeruginosa type III secretion system.

scientific article

Vfr Directly Activates exsA Transcription To Regulate Expression of the Pseudomonas aeruginosa Type III Secretion System.

scientific article published on 29 February 2016

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