List of works - Nicoletta Landsberger

A Novel Mecp2 Knock-in Model Displays Similar Behavioral Traits But Distinct Molecular Features Compared to the Mecp2-Null Mouse Implying Precision Medicine for the Treatment of Rett Syndrome

scientific article published on 06 November 2018

A binding protein (p82 protein) recognizes specifically the curved heterochromatic DNA in Artemia franciscana

scientific article published on 01 October 1990

A novel protein, Xenopus p20, influences the stability of MeCP2 through direct interaction.

scientific article

A novel transcript of cyclin-dependent kinase-like 5 (CDKL5) has an alternative C-terminus and is the predominant transcript in brain.

scientific article

ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules. ⬇️

scientific article published on 25 August 2016

ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.

scientific article published on October 2017

Autocrine and immune cell-derived BDNF in human skeletal muscle: implications for myogenesis and tissue regeneration

scientific article published on 12 August 2013

Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association

scientific article published on 21 June 2016

CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization

scientific article published on 5 February 2016

CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome

scientific article

CDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tail

scientific article

CDKL5 influences RNA splicing activity by its association to the nuclear speckle molecular machinery

scientific article

CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

scientific article published on 24 July 2017

Characterisation of CDKL5 Transcript Isoforms in Human and Mouse

scientific article

Chromatin and transcriptional activity in early Xenopus development.

scientific article published on August 1995

DNA methylation directs a time-dependent repression of transcription initiation ⬇️

scientific article published on March 1, 1997

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

scientific article published on 15 May 2015

Extrasynaptic N-Methyl-d-aspartate (NMDA) Receptor Stimulation Induces Cytoplasmic Translocation of the CDKL5 Kinase and Its Proteasomal Degradation ⬇️

scientific article published on August 5, 2011

Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation

scientific article

Highly repetitive DNA sequence in parthenogenetic Artemia

scientific article published on 01 January 1991

In Vitro Reconstitution of Artemia Satellite Chromatin ⬇️

scientific article published on July 17, 1998

Incorporation of mouse zona pellucida proteins into the envelope of Xenopus laevis oocytes

scientific article published in June 1999

LSD1 Neurospecific Alternative Splicing Controls Neuronal Excitability in Mouse Models of Epilepsy.

scientific article published on 15 April 2014

MECP2 mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders

scientific article published on 08 May 2020

MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms

scientific article

MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.

scientific article

MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?

scientific article

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization

scientific journal article

Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis

scientific article

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription ⬇️

scientific article (publication date: June 1998)

Nucleotide variation and molecular structure of the heterochromatic repetitive AluI DNA in the brine shrimp Artemia franciscana

scientific article published on 01 December 1992

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

scientific article published in May 2000

Phylogenetic study of bisexual Artemia using random amplified polymorphic DNA.

scientific article

Purification and characterization of a proteolytic active fragment of DNA topoisomerase I from the brine shrimp Artemia franciscana (Crustacea Anostraca) ⬇️

scientific article published on February 15, 1992

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.

scientific article published on 6 January 2011

Remodeling of regulatory nucleoprotein complexes on the Xenopus hsp70 promoter during meiotic maturation of the Xenopus oocyte

scientific article

Rescue of prepulse inhibition deficit and brain mitochondrial dysfunction by pharmacological stimulation of the central serotonin receptor 7 in a mouse model of CDKL5 Deficiency Disorder

article

Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action.

scientific article published on 02 March 2014

Spatio-temporal dynamics and localization of MeCP2 and pathological mutants in living cells.

scientific article published on 18 September 2007

Synaptic synthesis, dephosphorylation, and degradation: a novel paradigm for an activity-dependent neuronal control of CDKL5

scientific article

The Heat Shock Response in Xenopus Oocytes, Embryos, and Somatic Cells: A Regulatory Role for Chromatin ⬇️

scientific article published on July 1, 1995

The MeCP2/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis.

scientific article

The cDNA encoding Xenopus laevis heat-shock factor 1 (XHSF1): nucleotide and deduced amino-acid sequences, and properties of the encoded protein.

scientific article

The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes

scientific article published on 05 March 2021

The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA

scientific article published on 01 June 1999

The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex

scientific article

Trichostatin A decreases the levels of MeCP2 expression and phosphorylation and increases its chromatin binding affinity

scientific article

Tyr120Asp mutation alters domain flexibility and dynamics of MeCP2 DNA binding domain leading to impaired DNA interaction: Atomistic characterization of a Rett syndrome causing mutation.

scientific article published on 8 February 2018

What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathy

scientific article

Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo

scientific article

List of works by Nicoletta Landsberger

A Novel Mecp2 Knock-in Model Displays Similar Behavioral Traits But Distinct Molecular Features Compared to the Mecp2-Null Mouse Implying Precision Medicine for the Treatment of Rett Syndrome

A binding protein (p82 protein) recognizes specifically the curved heterochromatic DNA in Artemia franciscana

A novel protein, Xenopus p20, influences the stability of MeCP2 through direct interaction.

A novel transcript of cyclin-dependent kinase-like 5 (CDKL5) has an alternative C-terminus and is the predominant transcript in brain.

ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules. ⬇️

ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.

Autocrine and immune cell-derived BDNF in human skeletal muscle: implications for myogenesis and tissue regeneration

Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association

CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization

CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome

CDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tail

CDKL5 influences RNA splicing activity by its association to the nuclear speckle molecular machinery

CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

Characterisation of CDKL5 Transcript Isoforms in Human and Mouse

Chromatin and transcriptional activity in early Xenopus development.

DNA methylation directs a time-dependent repression of transcription initiation ⬇️

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

Extrasynaptic N-Methyl-d-aspartate (NMDA) Receptor Stimulation Induces Cytoplasmic Translocation of the CDKL5 Kinase and Its Proteasomal Degradation ⬇️

Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation

Highly repetitive DNA sequence in parthenogenetic Artemia

In Vitro Reconstitution of Artemia Satellite Chromatin ⬇️

Incorporation of mouse zona pellucida proteins into the envelope of Xenopus laevis oocytes

LSD1 Neurospecific Alternative Splicing Controls Neuronal Excitability in Mouse Models of Epilepsy.

MECP2 mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders

MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms

MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.

MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?

Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization

Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription ⬇️

Nucleotide variation and molecular structure of the heterochromatic repetitive AluI DNA in the brine shrimp Artemia franciscana

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

Phylogenetic study of bisexual Artemia using random amplified polymorphic DNA.

Purification and characterization of a proteolytic active fragment of DNA topoisomerase I from the brine shrimp Artemia franciscana (Crustacea Anostraca) ⬇️

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.

Remodeling of regulatory nucleoprotein complexes on the Xenopus hsp70 promoter during meiotic maturation of the Xenopus oocyte

Rescue of prepulse inhibition deficit and brain mitochondrial dysfunction by pharmacological stimulation of the central serotonin receptor 7 in a mouse model of CDKL5 Deficiency Disorder

Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action.

Spatio-temporal dynamics and localization of MeCP2 and pathological mutants in living cells.

Synaptic synthesis, dephosphorylation, and degradation: a novel paradigm for an activity-dependent neuronal control of CDKL5

The Heat Shock Response in Xenopus Oocytes, Embryos, and Somatic Cells: A Regulatory Role for Chromatin ⬇️

The MeCP2/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis.

The cDNA encoding Xenopus laevis heat-shock factor 1 (XHSF1): nucleotide and deduced amino-acid sequences, and properties of the encoded protein.

The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes

The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA

The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex

Trichostatin A decreases the levels of MeCP2 expression and phosphorylation and increases its chromatin binding affinity

Tyr120Asp mutation alters domain flexibility and dynamics of MeCP2 DNA binding domain leading to impaired DNA interaction: Atomistic characterization of a Rett syndrome causing mutation.

What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathy

Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo